Threonine

cyclin dependent kinase 2 ; Homo sapiens







111 Article(s)
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1 30700607 S-Like-Phase Cyclin-Dependent Kinases Stabilize the Epstein-Barr Virus BDLF4 Protein To Temporally Control Late Gene Transcription. 2019 Apr 15 1
2 30976006 Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation. 2019 Apr 11 1
3 31059711 Downregulation of miR-144 by triptolide enhanced p85α-PTEN complex formation causing S phase arrest of human nasopharyngeal carcinoma cells. 2019 Jul 15 2
4 31822694 Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27. 2019 Dec 10 1
5 29665367 Suppression of Akt-mediated HDAC3 expression and CDK2 T39 phosphorylation by a bichalcone analog contributes to S phase retardation of cancer cells. 2018 Jun 15 10
6 30039733 The dNTP triphosphohydrolase activity of SAMHD1 persists during S-phase when the enzyme is phosphorylated at T592. 2018 1
7 26450989 SUMOylation regulates p27Kip1 stability and localization in response to TGFβ. 2016 Feb 1
8 27815502 A Putative Cyclin-binding Motif in Human SAMHD1 Contributes to Protein Phosphorylation, Localization, and Stability. 2016 Dec 16 1
9 25736292 Cyclin-A-CDK2-mediated phosphorylation of CIZ1 blocks replisome formation and initiation of mammalian DNA replication. 2015 Apr 15 1
10 25860957 ING5 is phosphorylated by CDK2 and controls cell proliferation independently of p53. 2015 4
11 24732362 Protein phosphatase 1 dephosphorylates Orc2. 2014 May 9 2
12 24759790 Phosphorylation of CDK2 on threonine 160 influences silencing of sex chromosome during male meiosis. 2014 Jun 3
13 23853094 Foxp3 protein stability is regulated by cyclin-dependent kinase 2. 2013 Aug 23 1
14 22369944 Phosphorylation prevents C/EBPβ from the calpain-dependent degradation. 2012 Mar 16 1
15 22399317 Intrinsic protein flexibility in regulation of cell proliferation: advantages for signaling and opportunities for novel therapeutics. 2012 1
16 22415970 Resveratrol chemosensitizes breast cancer cells to melphalan by cell cycle arrest. 2012 Aug 2
17 22558186 CDK2 and PKA mediated-sequential phosphorylation is critical for p19INK4d function in the DNA damage response. 2012 1
18 22584582 Successive phosphorylation of p27(KIP1) protein at serine-10 and C terminus crucially controls its potency to inactivate Cdk2. 2012 Jun 22 2
19 23205069 Cell cycle-related kinase in carcinogenesis. 2012 Oct 2
20 21278485 Phosphorylation of EZH2 by CDK1 and CDK2: a possible regulatory mechanism of transmission of the H3K27me3 epigenetic mark through cell divisions. 2011 Feb 15 1
21 21965652 Phosphorylation of MCM3 protein by cyclin E/cyclin-dependent kinase 2 (Cdk2) regulates its function in cell cycle. 2011 Nov 18 2
22 20368335 Pro-apoptotic role of Cdc25A: activation of cyclin B1/Cdc2 by the Cdc25A C-terminal domain. 2010 Jun 4 1
23 20466538 Functional characterisation of cell cycle-related kinase (CCRK) in colorectal cancer carcinogenesis. 2010 Jun 2
24 20935635 Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2. 2010 Nov 2
25 19201832 CDK2 phosphorylation of Smad2 disrupts TGF-beta transcriptional regulation in resistant primary bone marrow myeloma cells. 2009 Feb 15 1
26 19233286 Differential phosphorylation patterns between the Cyclin-A2/CDK2 complex and their monomers. 2009 Jul 3
27 19320493 Peptide aptamers in label-free protein detection: 2. Chemical optimization and detection of distinct protein isoforms. 2009 May 1 1
28 19321444 Coordinated activation of the origin licensing factor CDC6 and CDK2 in resting human fibroblasts expressing SV40 small T antigen and cyclin E. 2009 May 22 1
29 19478079 O-linked N-acetylglucosamine modification on CCAAT enhancer-binding protein beta: role during adipocyte differentiation. 2009 Jul 17 2
30 19561638 Nucleophosmin protein expression level, but not threonine 198 phosphorylation, is essential in growth and proliferation. 2009 Sep 10 4
31 17997402 Differential regulation of the cyclin-dependent kinase inhibitors p21(Cip1) and p27(Kip1) by phosphorylation directed by the cyclin encoded by Murine Herpesvirus 68. 2008 Jan 1 1
32 18276582 Cyclin E and SV40 small T antigen cooperate to bypass quiescence and contribute to transformation by activating CDK2 in human fibroblasts. 2008 Apr 25 1
33 18354084 Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis. 2008 Apr 1 2
34 18383818 Cell cycle perturbation and acquired 5-fluorouracil chemoresistance. 2008 Jan-Feb 1
35 18495657 Mesalazine negatively regulates CDC25A protein expression and promotes accumulation of colon cancer cells in S phase. 2008 Jun 2
36 18519679 Mel-18 negatively regulates INK4a/ARF-independent cell cycle progression via Akt inactivation in breast cancer. 2008 Jun 1 1
37 18521083 Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells. 2008 Sep 11 1
38 18583928 Cell cycle-dependent phosphorylation of human CDC5 regulates RNA processing. 2008 Jun 15 1
39 18627125 Regulation of cell division by intrinsically unstructured proteins: intrinsic flexibility, modularity, and signaling conduits. 2008 Jul 22 1
40 17096381 Skp2-mediated p27(Kip1) degradation during S/G2 phase progression of adipocyte hyperplasia. 2007 Apr 1
41 17108053 Kaposi's sarcoma-associated herpesvirus-encoded protein kinase and its interaction with K-bZIP. 2007 Feb 1
42 17254966 Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases. 2007 Jan 26 1
43 17361108 Autocatalytic phosphorylation of CDK2 at the activating Thr160. 2007 Apr 1 8
44 17601773 Role of cdk2 in the sequential phosphorylation/activation of C/EBPbeta during adipocyte differentiation. 2007 Jul 10 3
45 17602833 The hedgehog pathway inhibitor cyclopamine increases levels of p27, and decreases both expression of IGF-II and activation of Akt in PC-3 prostate cancer cells. 2007 Oct 8 1
46 17636466 Computational study of the phosphoryl transfer catalyzed by a cyclin-dependent kinase. 2007 1
47 16376875 Thr199 phosphorylation targets nucleophosmin to nuclear speckles and represses pre-mRNA processing. 2006 Jan 23 4
48 16581786 The ETS protein MEF is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2. 2006 Apr 1
49 16880741 Reverse mutational analysis reveals threonine-373 as a potentially sufficient phosphorylation site for inactivation of the retinoblastoma tumor suppressor protein (pRB). 2006 Aug 1
50 17015463 Interaction between ROCK II and nucleophosmin/B23 in the regulation of centrosome duplication. 2006 Dec 4