Guanosine Triphosphate

ras homolog family member A ; Mus musculus







58 Article(s)
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1 33576779 Angiotensin II receptor 1 controls profibrotic Wnt/β-catenin signalling in experimental autoimmune myocarditis. 2022 Jan 29 1
2 35460881 BKM120 alters the migration of doublecortin-positive cells in the dentate gyrus of mice. 2022 May 2
3 34390950 Disrupting RhoA activity by blocking Arhgef3 expression mitigates microglia-induced neuroinflammation post spinal cord contusion. 2021 Oct 15 2
4 32587503 Arhgef5 Binds α-Dystrobrevin 1 and Regulates Neuromuscular Junction Integrity. 2020 1
5 32890901 AMPK inhibition protects against arterial thrombosis while sparing hemostasis through differential modulation of platelet responses. 2020 Dec 1
6 30159893 NKCC1 promotes EMT-like process in GBM via RhoA and Rac1 signaling pathways. 2019 Feb 1
7 30778044 P2Y12 regulates microglia activation and excitatory synaptic transmission in spinal lamina II neurons during neuropathic pain in rodents. 2019 Feb 18 2
8 31722730 P2Y12 receptor mediates microglial activation via RhoA/ROCK pathway in the trigeminal nucleus caudalis in a mouse model of chronic migraine. 2019 Nov 13 1
9 29393423 COL1A1 promotes metastasis in colorectal cancer by regulating the WNT/PCP pathway. 2018 Apr 1
10 29481523 Flavonoids extracted from leaves of Diospyros kaki regulates RhoA activity to rescue synapse loss and reverse memory impairment in APP/PS1 mice. 2018 May 2 4
11 29873419 p-Hydroxylcinnamaldehyde slows the progression of 4NQO-induced oesophageal tumourigenesis via the RhoA-MAPK signaling pathway. 2018 Oct 1
12 30301147 Prostaglandin D₂ Induces Ca2+ Sensitization of Contraction without Affecting Cytosolic Ca2+ Level in Bronchial Smooth Muscle. 2018 Oct 5 2
13 27633771 Annexin A1 restores Aβ1-42 -induced blood-brain barrier disruption through the inhibition of RhoA-ROCK signaling pathway. 2017 Feb 2
14 28115390 Inhibition of KLF5-Myo9b-RhoA Pathway-Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm. 2017 Mar 3 2
15 26908598 Loss of human disease protein retinitis pigmentosa GTPase regulator (RPGR) differentially affects rod or cone-enriched retina. 2016 Apr 1 1
16 27188168 P-Hydroxycinnamaldehyde Induces B16-F1 Melanoma Cell Differentiation via the RhoA-MAPK Signaling Pathway. 2016 1
17 25545473 Cannabinoid receptor 1 but not 2 mediates macrophage phagocytosis by G(α)i/o /RhoA/ROCK signaling pathway. 2015 Jul 2
18 25683353 Noise-induced cochlear F-actin depolymerization is mediated via ROCK2/p-ERM signaling. 2015 Jun 1
19 25911102 Structural and Biochemical Basis for the Inhibitory Effect of Liprin-α3 on Mouse Diaphanous 1 (mDia1) Function. 2015 Jun 5 1
20 26416580 Inhibition of the Rho/Rho kinase pathway prevents lipopolysaccharide-induced hyperalgesia and the release of TNF-α and IL-1β in the mouse spinal cord. 2015 Sep 29 1
21 24240172 IκB kinase γ/nuclear factor-κB-essential modulator (IKKγ/NEMO) facilitates RhoA GTPase activation, which, in turn, activates Rho-associated KINASE (ROCK) to phosphorylate IKKβ in response to transforming growth factor (TGF)-β1. 2014 Jan 17 7
22 23523587 Type VIII collagen signals via β1 integrin and RhoA to regulate MMP-2 expression and smooth muscle cell migration. 2013 Aug 8 1
23 23559363 Small GTPase Rap1 regulates cell migration through regulation of small GTPase RhoA activity in response to transforming growth factor-β1. 2013 Nov 5
24 23707391 Involvement of small GTPase RhoA in the regulation of superoxide production in BV2 cells in response to fibrillar Aβ peptides. 2013 Sep 1
25 22333836 Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis. 2012 Apr 15 1
26 22363657 RHGF-2 is an essential Rho-1 specific RhoGEF that binds to the multi-PDZ domain scaffold protein MPZ-1 in Caenorhabditis elegans. 2012 1
27 23001747 Crystal structure of mouse RhoA:GTPγS complex in a centered lattice. 2012 Dec 4
28 20558775 Heparin inhibits pulmonary artery smooth muscle cell proliferation through guanine nucleotide exchange factor-H1/RhoA/Rho kinase/p27. 2011 Apr 1
29 21266780 Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice. 2011 Feb 1
30 21302283 LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells. 2011 Nov 1
31 21999228 RhoA activation and effect of Rho-kinase inhibitor in the development of retinal neovascularization in a mouse model of oxygen-induced retinopathy. 2011 Nov 3
32 19361585 Rho GTPase signaling and PTH 3-34, but not PTH 1-34, maintain the actin cytoskeleton and antagonize bisphosphonate effects in mouse osteoblastic MC3T3-E1 cells. 2009 Jul 1
33 19553472 The low-affinity receptor for neurotrophins p75NTR plays a key role for satellite cell function in muscle repair acting via RhoA. 2009 Aug 1
34 19584242 Renal and liver tumors in Tsc2(+/-) mice, a model of tuberous sclerosis complex, do not respond to treatment with atorvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. 2009 Jul 1
35 19745197 Tumor necrosis factor-alpha potentiates RhoA-mediated monocyte transmigratory activity in vivo at a picomolar level. 2009 Dec 2
36 18495474 Pentoxifylline impedes migration in B16F10 melanoma by modulating Rho GTPase activity and actin organisation. 2008 Jul 1
37 18676845 Fibroblast growth factor 2 restrains Ras-driven proliferation of malignant cells by triggering RhoA-mediated senescence. 2008 Aug 1 1
38 18045963 Vasopressin triggers senescence in K-ras transformed cells via RhoA-dependent downregulation of cyclin D1. 2007 Dec 1
39 15743890 A role for Rho and Rac in secretagogue-induced amylase release by pancreatic acini. 2005 Jul 1
40 15746689 Tocolytic effect of a Rho-kinase inhibitor in a mouse model of lipopolysaccharide-induced preterm delivery. 2005 Mar 1
41 16023319 Wisteria floribunda gall extract inhibits cell migration in mouse B16F1 melanoma cells by regulating CD44 expression and GTP-RhoA activity. 2005 Oct 31 4
42 15102857 RhoA/ROCK activation by growth hormone abrogates p300/histone deacetylase 6 repression of Stat5-mediated transcription. 2004 Jul 30 2
43 12654918 Serine phosphorylation negatively regulates RhoA in vivo. 2003 May 23 1
44 12702722 Direct interaction of focal adhesion kinase with p190RhoGEF. 2003 Jul 4 1
45 12734402 The SH4-Unique-SH3-SH2 domains dictate specificity in signaling that differentiate c-Yes from c-Src. 2003 Jun 15 1
46 12860969 Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system. 2003 Jul 21 2
47 12948935 Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells. 2003 Dec 2
48 14513355 Characterization of leukemia-associated Rho guanine nucleotide exchange factor (LARG) expression during murine development. 2003 Dec 1
49 11841578 Geldanamycin specifically modulates thrombin-mediated morphological changes in mouse neuroblasts. 2002 Feb 1
50 12215546 RhoGEF specificity mutants implicate RhoA as a target for Dbs transforming activity. 2002 Oct 1