Title : Noise-induced cochlear F-actin depolymerization is mediated via ROCK2/p-ERM signaling.

Pub. Date : 2015 Jun

PMID : 25683353






1 Functional Relationships(s)
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1 We propose the following cascade following noise trauma leading to alteration of the F-actin arrangement in the outer hair cell cytoskeleton: Noise exposure reduces the levels of GTP-RhoA and subsequently diminishes levels of RhoA effector ROCK2 (Rho-associated kinase 2). Guanosine Triphosphate ras homolog family member A Mus musculus