Endocannabinoids

fatty acid amide hydrolase ; Mus musculus







63 Article(s)
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1 34449902 The effects of systemic and local fatty acid amide hydrolase and monoacylglycerol lipase inhibitor treatments on the metabolomic profile of lungs. 2022 Jan 1
2 33016621 Inhibition of fatty acid amide hydrolase prevents pathology in neurovisceral acid sphingomyelinase deficiency by rescuing defective endocannabinoid signaling. 2020 Nov 6 1
3 31004320 Effects of Fatty Acid Amide Hydrolase Inhibitors Acute Administration on the Positive and Cognitive Symptoms of Schizophrenia in Mice. 2019 Nov 2
4 31437772 Formation of HETE-EAs and dihydroxy derivatives in mouse kidney tissue and analysis by high-performance liquid chromatography tandem mass spectrometry. 2019 Sep 15 2
5 28660730 Fatty acid amide hydrolase (FAAH) inactivation confers enhanced sensitivity to nicotine-induced dopamine release in the mouse nucleus accumbens. 2018 Mar 2
6 29228105 Metformin attenuates susceptibility to inflammation-induced preterm birth in mice with higher endocannabinoid levels. 2018 Feb 1 1
7 29846106 Modulation of mean arterial pressure and diuresis by renomedullary infusion of a selective inhibitor of fatty acid amide hydrolase. 2018 Oct 1 2
8 30085402 Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain. 2018 Oct 8 2
9 30411058 Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors. 2018 Oct 31 2
10 27731508 Peripheral Blood Mononuclear Cells Infiltration Downregulates Decidual FAAH Activity in an LPS-Induced Embryo Resorption Model. 2017 Jun 1
11 28673548 Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB1 receptor-mediated discriminative stimulus in mice. 2017 Oct 2
12 29367955 Pharmacological Inhibition of Brain Fatty Acid Binding Protein Reduces Ethanol Consumption in Mice. 2017 2
13 26930716 Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells. 2016 Mar 22 4
14 26935536 Role of Cannabinoids in Gastrointestinal Mucosal Defense and Inflammation. 2016 1
15 27001846 Individual differences in frontolimbic circuitry and anxiety emerge with adolescent changes in endocannabinoid signaling across species. 2016 Apr 19 2
16 27109320 Broad impact of deleting endogenous cannabinoid hydrolyzing enzymes and the CB1 cannabinoid receptor on the endogenous cannabinoid-related lipidome in eight regions of the mouse brain. 2016 Aug 2
17 27126057 Systemic and spinal administration of FAAH, MAGL inhibitors and dual FAAH/MAGL inhibitors produce antipruritic effect in mice. 2016 Jul 2
18 27178246 A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase. 2016 2
19 24571443 Impaired neurogenesis by HIV-1-Gp120 is rescued by genetic deletion of fatty acid amide hydrolase enzyme. 2015 Oct 1
20 24915981 Attenuation of serotonin-induced itch responses by inhibition of endocannabinoid degradative enzymes, fatty acid amide hydrolase and monoacylglycerol lipase. 2015 Mar 1
21 25479915 Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice. 2015 Jan 1 2
22 25715681 Endocannabinoid Catabolic Enzymes Play Differential Roles in Thermal Homeostasis in Response to Environmental or Immune Challenge. 2015 Jun 2
23 25757568 Multitarget fatty acid amide hydrolase/cyclooxygenase blockade suppresses intestinal inflammation and protects against nonsteroidal anti-inflammatory drug-dependent gastrointestinal damage. 2015 Jun 2
24 25979787 Endocannabinoid-mediated improvement on a test of aversive memory in a mouse model of fragile X syndrome. 2015 Sep 15 1
25 25998048 Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice. 2015 Aug 2
26 26157003 Multiple Forms of Endocannabinoid and Endovanilloid Signaling Regulate the Tonic Control of GABA Release. 2015 Jul 8 1
27 26406890 Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor. 2015 1
28 24286707 Inhibition of endocannabinoid-degrading enzyme fatty acid amide hydrolase increases atherosclerotic plaque vulnerability in mice. 2014 Jan 1
29 24361246 Organophosphate agents induce plasma hypertriglyceridemia in mouse via single or dual inhibition of the endocannabinoid hydrolyzing enzyme(s). 2014 Feb 10 2
30 24460851 Selective inhibition of FAAH produces antidiarrheal and antinociceptive effect mediated by endocannabinoids and cannabinoid-like fatty acid amides. 2014 Apr 1
31 24530133 Experimental colitis in mice is attenuated by changes in the levels of endocannabinoid metabolites induced by selective inhibition of fatty acid amide hydrolase (FAAH). 2014 Sep 2
32 25539508 Cocaine-induced behavioral sensitization is associated with changes in the expression of endocannabinoid and glutamatergic signaling systems in the mouse prefrontal cortex. 2014 Oct 31 2
33 23303065 Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice. 2013 May 1
34 23911581 Piperazinyl carbamate fatty acid amide hydrolase inhibitors and transient receptor potential channel modulators as "dual-target" analgesics. 2013 Oct 2
35 24167249 Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction. 2013 Nov 12 2
36 24191036 Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase. 2013 Nov 19 2
37 22321194 β-Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR-α, PPAR-γ and TRPV1, but not CB₁ or CB₂ receptors. 2012 Jun 2
38 22420940 Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions. 2012 May 2
39 22860206 Endogenous molecules stimulating N-acylethanolamine-hydrolyzing acid amidase (NAAA). 2012 May 16 2
40 22915616 Inactivation of fatty acid amide hydrolase exacerbates experimental fibrosis by enhanced endocannabinoid-mediated activation of CB1. 2012 Dec 1
41 20559305 The CB₁ receptor antagonist SR141716A reverses adult male mice overweight and metabolic alterations induced by early stress. 2011 Jan 2
42 21070851 Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury. 2011 Jan 1 1
43 21097653 An anatomical and temporal portrait of physiological substrates for fatty acid amide hydrolase. 2011 Feb 2
44 21740924 Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice. 2011 Oct 2
45 20424126 Preservation of striatal cannabinoid CB1 receptor function correlates with the antianxiety effects of fatty acid amide hydrolase inhibition. 2010 Aug 2
46 20554481 Fatty acid amide hydrolase and monoacylglycerol lipase inhibitors produce anti-allodynic effects in mice through distinct cannabinoid receptor mechanisms. 2010 Dec 2
47 19430909 Inhibitors of endocannabinoid-metabolizing enzymes reduce precipitated withdrawal responses in THC-dependent mice. 2009 Jun 2
48 19555737 Temporal changes in mouse brain fatty acid amide hydrolase activity. 2009 Oct 6 2
49 17709120 Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors. 2008 Jan 4
50 18451315 The endogenous cannabinoid system modulates nicotine reward and dependence. 2008 Aug 2