Fatty Acids

carnitine palmitoyltransferase 1a, liver ; Mus musculus







53 Article(s)
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1 34413485 Targeting Cpt1a-Bcl-2 interaction modulates apoptosis resistance and fibrotic remodeling. 2022 Jan 1
2 34837783 Carnitine palmitoyltransferase 1A is essential for decidualization in mice. 2022 Jan 15 2
3 34976224 Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation. 2022 1
4 35223522 Decrease of Intracellular Glutamine by STF-62247 Results in the Accumulation of Lipid Droplets in von Hippel-Lindau Deficient Cells. 2022 2
5 35428314 L-theanine prevents progression of nonalcoholic hepatic steatosis by regulating hepatocyte lipid metabolic pathways via the CaMKKβ-AMPK signaling pathway. 2022 Apr 15 2
6 33465052 Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis. 2021 Mar 1 1
7 33517883 Etomoxir regulates the differentiation of male germ cells by specifically reducing H3K27ac level. 2021 Feb 1 1
8 34035164 Butyrate enhances CPT1A activity to promote fatty acid oxidation and iTreg differentiation. 2021 Jun 1 1
9 34073834 P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid β-Oxidation through AMPK and PGC-1α Induction in High-Fat Diet-Fed Mice. 2021 May 24 2
10 34281337 γ-Linolenic Acid Prevents Lipid Metabolism Disorder in Palmitic Acid-Treated Alpha Mouse Liver-12 Cells by Balancing Autophagy and Apoptosis via the LKB1-AMPK-mTOR Pathway. 2021 Jul 28 1
11 34361032 Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Diet-Induced Obesity in Mice. 2021 Jul 31 1
12 34415766 Novel ι-Carrageenan Tetrasaccharide Alleviates Liver Lipid Accumulation via the Bile Acid-FXR-SHP/PXR Pathway to Regulate Cholesterol Conversion and Fatty Acid Metabolism in Insulin-Resistant Mice. 2021 Sep 1 2
13 34433035 Macrophage HIF-2α suppresses NLRP3 inflammasome activation and alleviates insulin resistance. 2021 Aug 24 1
14 34607257 The alleviating effect of sphingosine kinases 2 inhibitor K145 on nonalcoholic fatty liver. 2021 Nov 26 1
15 34680102 Rosmarinic Acid Exhibits a Lipid-Lowering Effect by Modulating the Expression of Reverse Cholesterol Transporters and Lipid Metabolism in High-Fat Diet-Fed Mice. 2021 Oct 6 2
16 34900534 Integrative lipidomic and transcriptomic study unravels the therapeutic effects of saikosaponins A and D on non-alcoholic fatty liver disease. 2021 Nov 1
17 32043636 REDD1 deficiency protects against nonalcoholic hepatic steatosis induced by high-fat diet. 2020 Apr 1
18 32256954 Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation. 2020 1
19 32309378 Yin Zhi Huang, a traditional Chinese herbal formula, ameliorates diet-induced obesity and hepatic steatosis by activating the AMPK/SREBP-1 and the AMPK/ACC/CPT1A pathways. 2020 Mar 1
20 33352903 Targeting Fat Oxidation in Mouse Prostate Cancer Decreases Tumor Growth and Stimulates Anti-Cancer Immunity. 2020 Dec 18 1
21 30453390 PPARβ/δ-agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1ΔE9 astrocytes. 2019 Jan 1
22 30909319 SLC1A5 glutamine transporter is a target of MYC and mediates reduced mTORC1 signaling and increased fatty acid oxidation in long-lived Myc hypomorphic mice. 2019 Jun 1
23 31577975 Ginsenoside Rb3 regulates energy metabolism and apoptosis in cardiomyocytes via activating PPARα pathway. 2019 Dec 1
24 31823799 CPT1a gene expression reverses the inflammatory and anti-phagocytic effect of 7-ketocholesterol in RAW264.7 macrophages. 2019 Dec 10 1
25 29396649 Ghrelin Causes a Decline in GABA Release by Reducing Fatty Acid Oxidation in Cortex. 2018 Sep 1
26 29668854 Prostate cancer chemoprevention by sulforaphane in a preclinical mouse model is associated with inhibition of fatty acid metabolism. 2018 May 28 2
27 29891006 Disrupting SOD1 activity inhibits cell growth and enhances lipid accumulation in nasopharyngeal carcinoma. 2018 Jun 11 1
28 29901078 Farnesoid X receptor agonist decreases lipid accumulation by promoting hepatic fatty acid oxidation in db/db mice. 2018 Sep 1
29 30300835 Long-term exposure to high-sucrose diet down-regulates hepatic endoplasmic reticulum-stress adaptive pathways and potentiates de novo lipogenesis in weaned male mice. 2018 Dec 1
30 30333041 Rosiglitazone ameliorates palmitic acid-induced cytotoxicity in TM4 Sertoli cells. 2018 Oct 17 3
31 30443192 DJ-1 Deficiency Protects Hepatic Steatosis by Enhancing Fatty Acid Oxidation in Mice. 2018 1
32 27973789 Effects of Polar Compounds Generated from the Deep-Frying Process of Palm Oil on Lipid Metabolism and Glucose Tolerance in Kunming Mice. 2017 Jan 11 1
33 28024299 The role of fatty acid β-oxidation in lymphangiogenesis. 2017 Feb 2 2
34 28515141 Glucagon-induced extracellular cAMP regulates hepatic lipid metabolism. 2017 Aug 1
35 28722145 Dendrobium nobile Lindl. alkaloids regulate metabolism gene expression in livers of mice. 2017 Oct 1
36 29091708 HIMH0021 attenuates ethanol-induced liver injury and steatosis in mice. 2017 1
37 29173234 Dietary α-lactalbumin induced fatty liver by enhancing nuclear liver X receptor αβ/sterol regulatory element-binding protein-1c/PPARγ expression and minimising PPARα/carnitine palmitoyltransferase-1 expression and AMP-activated protein kinase α phosphorylation associated with atherogenic dyslipidaemia, insulin resistance and oxidative stress in Balb/c mice. 2017 Dec 2
38 26832401 Inborn Errors of Long-Chain Fatty Acid β-Oxidation Link Neural Stem Cell Self-Renewal to Autism. 2016 Feb 9 1
39 27199763 Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation. 2016 1
40 27455510 NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages. 2016 Sep 2
41 27727308 Circadian and Dopaminergic Regulation of Fatty Acid Oxidation Pathway Genes in Retina and Photoreceptor Cells. 2016 1
42 27941940 Kefir peptides prevent high-fructose corn syrup-induced non-alcoholic fatty liver disease in a murine model by modulation of inflammation and the JAK2 signaling pathway. 2016 Dec 12 2
43 25646773 Livers with constitutive mTORC1 activity resist steatosis independent of feedback suppression of Akt. 2015 1
44 25210128 Steroidogenesis in MA-10 mouse Leydig cells is altered via fatty acid import into the mitochondria. 2014 Oct 1
45 23533380 Inhibitors of Fatty Acid Synthesis Induce PPAR α -Regulated Fatty Acid β -Oxidative Genes: Synergistic Roles of L-FABP and Glucose. 2013 1
46 24019513 Lipid absorption defects in intestine-specific microsomal triglyceride transfer protein and ATP-binding cassette transporter A1-deficient mice. 2013 Oct 18 1
47 21348853 Carnitine palmitoyltransferase 1A prevents fatty acid-induced adipocyte dysfunction through suppression of c-Jun N-terminal kinase. 2011 May 1 4
48 22229081 Long term effects of high fat or high carbohydrate diets on glucose tolerance in mice with heterozygous carnitine palmitoyltransferase-1a (CPT-1a) deficiency: Diet influences on CPT1a deficient mice. 2011 Aug 22 1
49 18719599 Regulation of food intake and energy expenditure by hypothalamic malonyl-CoA. 2008 Sep 2
50 16762007 Fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, reduces hepatic steatosis and lipid peroxidation in fatty liver Shionogi mice with hereditary fatty liver. 2006 Jun 1