Pub. Date : 2020
PMID : 32850832
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Nucleotide-Binding Oligomerization Domain-Like Receptor 3 Deficiency Attenuated Isoproterenol-Induced Cardiac Fibrosis via Reactive Oxygen Species/High Mobility Group Box 1 Protein Axis. | Reactive Oxygen Species | NLR family, pyrin domain containing 3 | Mus musculus |
2 | We found that NLRP3 could regulate high-mobility group box 1 protein (HMGB1) secretion via reactive oxygen species production in NRVMs and the HMGB1 secreted by NRVMs promoted the activation and proliferation of cardiac fibroblasts. | Reactive Oxygen Species | NLR family, pyrin domain containing 3 | Mus musculus |