Y 27632

Rho associated coiled-coil containing protein kinase 1 ; Homo sapiens







54 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34820002 Cancer-associated fibroblasts as cellular vehicles in endometrial cancer cell migration. 2022 Jan 1
2 35605366 Molecular mechanisms underlying the heterogeneous barrier responses of two primary endothelial cell types to sphingosine-1-phosphate. 2022 May 11 2
3 33717260 The miR-136-5p/ROCK1 axis suppresses invasion and migration, and enhances cisplatin sensitivity in head and neck cancer cells. 2021 Apr 2
4 32265034 Pyk2 downstream of G12/13 pathways regulates platelet shape change through RhoA/p160ROCK. 2020 Jun 4 1
5 32417439 ATPR induces acute promyelocytic leukemia cells differentiation and growth arrest by blockade of SHP2/Rho/ROCK1 pathway. 2020 Jul 15 2
6 32946790 Yes-associated protein 1 translocation through actin cytoskeleton organization in trophectoderm cells. 2020 Dec 1 1
7 33219246 ROCK inhibitors beneficially alter the spatial configuration of TGFβ2-treated 3D organoids from a human trabecular meshwork (HTM). 2020 Nov 20 1
8 33633690 Tissue-Specific Approaches Reveal Diverse Metabolic Functions of Rho-Kinase 1. 2020 1
9 30592323 Hypoxia-induced ARHGAP26 deficiency inhibits the proliferation and migration of human ductus arteriosus smooth muscle cell through activating RhoA-ROCK-PTEN pathway. 2019 Jun 1
10 29414040 Identification and characterization of the druggable kinase targets of olmesartan and its analogues from a systematic kinase-chemical interaction profile in atherosclerosis. 2018 Mar 1
11 29804125 Rho Kinase Type 1 (ROCK1) Promotes Lipopolysaccharide-induced Inflammation in Corneal Epithelial Cells by Activating Toll-Like Receptor 4 (TLR4)-Mediated Signaling. 2018 May 27 3
12 29849894 A Positive Feedback Loop of Profilin-1 and RhoA/ROCK1 Promotes Endothelial Dysfunction and Oxidative Stress. 2018 1
13 30066939 Lycorine inhibits cell proliferation and migration by inhibiting ROCK1/cofilin‑induced actin dynamics in HepG2 hepatoblastoma cells. 2018 Oct 1
14 30165352 Distinct Roles For ROCK1 and ROCK2 in the Regulation of Oxldl-Mediated Endothelial Dysfunction. 2018 1
15 30185878 Histamine causes endothelial barrier disruption via Ca2+-mediated RhoA activation and tension at adherens junctions. 2018 Sep 5 1
16 30187871 [Biejiajian Pills inhibits hepatoma carcinoma cell vasculogenic mimicry by suppressing RhoA/ROCK signaling pathway]. 2018 Jul 30 1
17 27841867 Rho-associated kinase 1 inhibition is synthetically lethal with von Hippel-Lindau deficiency in clear cell renal cell carcinoma. 2017 Feb 23 2
18 28042775 Inhibition of Epithelial-mesenchymal Transition in Response to Treatment with Metformin and Y27632 in Breast Cancer Cell Lines. 2017 1
19 26901778 Rho Kinase ROCK2 Mediates Acid-Induced NADPH Oxidase NOX5-S Expression in Human Esophageal Adenocarcinoma Cells. 2016 1
20 27432870 Heterogeneous Impact of ROCK2 on Carotid and Cerebrovascular Function. 2016 Sep 1
21 25755711 Overexpression of ROCK1 and ROCK2 inhibits human laryngeal squamous cell carcinoma. 2015 1
22 24430196 The effect of Rho-associated kinase inhibition on the proteome pattern of dissociated human embryonic stem cells. 2014 Mar 4 2
23 24457551 RhoC mediates invasion and migration of CaSki cells through the Rho-associated serine-threonine protein kinase 1 signaling pathway. 2014 Feb 2
24 25069775 ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium. 2014 Sep 1
25 25077932 Alternative cultures for human pluripotent stem cell production, maintenance, and genetic analysis. 2014 Jul 24 1
26 25288205 A novel small-molecule MRCK inhibitor blocks cancer cell invasion. 2014 Oct 5 1
27 23134219 Expression of serum response factor in gastric carcinoma and its molecular mechanisms involved in the regulation of the invasion and migration of SGC-7901 cells. 2013 Mar 2
28 23211630 ROCK2 regulates bFGF-induced proliferation of SH-SY5Y cells through GSK-3β and β-catenin pathway. 2013 Jan 25 1
29 23347954 H1152 promotes the degradation of polyglutamine-expanded ataxin-3 or ataxin-7 independently of its ROCK-inhibiting effect and ameliorates mutant ataxin-3-induced neurodegeneration in the SCA3 transgenic mouse. 2013 Jul 2
30 23936026 microRNA-124 inhibits migration and invasion by down-regulating ROCK1 in glioma. 2013 1
31 22913419 Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients. 2012 Aug 22 1
32 21302311 The suppression of myosin light chain (MLC) phosphorylation during the response to lipopolysaccharide (LPS): beneficial or detrimental to endothelial barrier? 2011 Dec 1
33 22130238 Decreases in CD31 and CD47 levels on the cell surface during etoposide-induced Jurkat cell apoptosis. 2011 1
34 20012714 Presence of a ROCK inhibitor in extracellular matrix supports more undifferentiated growth of feeder-free human embryonic and induced pluripotent stem cells upon passaging. 2010 Mar 2
35 20661774 Ouabain-induced apoptosis and Rho kinase: a novel caspase-2 cleavage site and fragment of Rock-2. 2010 Dec 1
36 19133144 Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin. 2009 Jan 8 1
37 19144696 Cytokine-induced F-actin reorganization in endothelial cells involves RhoA activation. 2009 Mar 1
38 19260014 Human embryonic stem cells: caught between a ROCK inhibitor and a hard place. 2009 Mar 1
39 19278999 Inhibition of Rho kinases enhances the degradation of mutant huntingtin. 2009 May 8 3
40 18573880 Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation. 2008 Sep 1
41 17009325 Molecular characterization of the effects of Y-27632. 2007 Feb 2
42 16513651 Effects of peripheral cannabinoid receptor ligands on motility and polarization in neutrophil-like HL60 cells and human neutrophils. 2006 May 5 1
43 16784244 Phosphoryl transfer is not rate-limiting for the ROCK I-catalyzed kinase reaction. 2006 Jun 27 1
44 15681706 Lysophosphatidic acid-mediated augmentation of cardiomyocyte lipoprotein lipase involves actin cytoskeleton reorganization. 2005 Jun 1
45 15220352 Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes. 2004 Sep 10 1
46 15254210 Human cytomegalovirus-encoded G protein-coupled receptor US28 mediates smooth muscle cell migration through Galpha12. 2004 Aug 1
47 12466151 Polyamines regulate Rho-kinase and myosin phosphorylation during intestinal epithelial restitution. 2003 Apr 1
48 12799187 Rho protein-mediated changes in the structure of the actin cytoskeleton regulate human inducible NO synthase gene expression. 2003 Jul 1 1
49 12850840 Dynamic regulation of microtubule coils in ADP-induced platelet shape change by p160ROCK (Rho-kinase). 2003 May 1
50 12857854 Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells. 2003 Jul 1