Tyrosine

vav guanine nucleotide exchange factor 1 ; Homo sapiens







168 Article(s)
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1 34414199 Downregulation of CD45 Signaling in COVID-19 Patients Is Reversed by C24D, a Novel CD45 Targeting Peptide. 2021 1
2 32561640 The guanine nucleotide exchange factor VAV3 participates in ERBB4-mediated cancer cell migration. 2020 Aug 14 1
3 31644919 Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation. 2019 Oct 22 2
4 29991650 The costimulatory molecule CD226 signals through VAV1 to amplify TCR signals and promote IL-17 production by CD4+ T cells. 2018 Jul 10 1
5 25723543 Role of cortactin homolog HS1 in transendothelial migration of natural killer cells. 2015 1
6 26043137 Vav1 Regulates T-Cell Activation through a Feedback Mechanism and Crosstalk between the T-Cell Receptor and CD28. 2015 Jul 2 3
7 26353933 Vav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancer. 2015 Oct 6 1
8 24736456 The C-terminal SH3 domain contributes to the intramolecular inhibition of Vav family proteins. 2014 Apr 15 1
9 25483299 Vav family exchange factors: an integrated regulatory and functional view. 2014 1
10 23258536 Role of Src homology domain binding in signaling complexes assembled by the murid γ-herpesvirus M2 protein. 2013 Feb 8 2
11 23325923 c-Abl tyrosine kinase plays a critical role in β2 integrin-dependent neutrophil migration by regulating Vav1 activity. 2013 Apr 2
12 23955592 Differential recognition of syk-binding sites by each of the two phosphotyrosine-binding pockets of the Vav SH2 domain. 2013 Nov 1
13 22786724 Complementary phosphorylation sites in the adaptor protein SLP-76 promote synergistic activation of natural killer cells. 2012 Jul 10 2
14 21606197 Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav. 2011 Jul 3
15 19747912 Vav1 and PU.1 are recruited to the CD11b promoter in APL-derived promyelocytes: role of Vav1 in modulating PU.1-containing complexes during ATRA-induced differentiation. 2010 Jan 1 1
16 20028078 Mass spectrometry-based identification of Y745 of Vav1 as a tyrosine residue crucial in maturation of acute promyelocytic leukemia-derived cells. 2010 Feb 5 6
17 20457609 Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity. 2010 Jul 23 4
18 20564190 PI3K is involved in L-selectin- and PSGL-1-mediated neutrophil rolling on E-selectin via F-actin redistribution and assembly. 2010 Jul 1 1
19 20644716 Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production. 2010 Jul 13 1
20 19100858 Vav1: a hematopoietic signal transduction molecule involved in human malignancies. 2009 Jun 2
21 19234221 c-Abl kinase is required for beta 2 integrin-mediated neutrophil adhesion. 2009 Mar 1 1
22 19533802 The haematopoietic specific signal transducer Vav1 is aberrantly expressed in lung cancer and plays a role in tumourigenesis. 2009 Sep 2
23 19672294 Vav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic Guanine nucleotide exchange activity. 2009 Aug 12 1
24 19833725 Tyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFAT. 2009 Dec 4 1
25 18301737 The Gammaherpesvirus m2 protein manipulates the Fyn/Vav pathway through a multidocking mechanism of assembly. 2008 Feb 27 1
26 18642942 Vav1 modulates protein expression during ATRA-induced maturation of APL-derived promyelocytes: a proteomic-based analysis. 2008 Sep 2
27 18835194 Inhibitory receptor signaling via tyrosine phosphorylation of the adaptor Crk. 2008 Oct 17 1
28 17339478 The granulocyte receptor carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) directly associates with Vav to promote phagocytosis of human pathogens. 2007 Mar 15 2
29 17590270 Flesh and blood: the story of Vav1, a gene that signals in hematopoietic cells but can be transforming in human malignancies. 2007 Oct 8 1
30 17855053 The association of Sam68 with Vav1 contributes to tumorigenesis. 2007 Dec 1
31 16434390 Dissociation of recruitment and activation of the small G-protein Rac during Fcgamma receptor-mediated phagocytosis. 2006 Mar 31 1
32 16449524 Protein-tyrosine kinase Syk is required for pathogen engulfment in complement-mediated phagocytosis. 2006 Jun 1 1
33 16882714 The Vav binding site of the non-receptor tyrosine kinase Syk at Tyr 348 is critical for beta2 integrin (CD11/CD18)-mediated neutrophil migration. 2006 Dec 1 1
34 17050525 Vav1 acidic region tyrosine 174 is required for the formation of T cell receptor-induced microclusters and is essential in T cell development and activation. 2006 Dec 15 9
35 15699036 Beta3 tyrosine phosphorylation and alphavbeta3-mediated adhesion are required for Vav1 association and Rho activation in leukocytes. 2005 Apr 15 2
36 15878332 Vav promotes differentiation of human tumoral myeloid precursors. 2005 May 15 6
37 15944312 Critical role of proline-rich tyrosine kinase 2 in reversion of the adhesion-mediated suppression of reactive oxygen species generation by human neutrophils. 2005 Jun 15 1
38 16160144 Characterization of the Kaposi's sarcoma-associated herpesvirus K1 signalosome. 2005 Oct 1
39 16285729 Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain. 2005 Nov 22 1
40 14709332 Association of PI 3-K with tyrosine phosphorylated Vav is essential for its activity in neutrophil-like maturation of myeloid cells. 2004 Apr 4
41 14757747 Differential regulation of TCR-mediated gene transcription by Vav family members. 2004 Feb 2 1
42 15147561 Tethered ligand-derived peptides of proteinase-activated receptor 3 (PAR3) activate PAR1 and PAR2 in Jurkat T cells. 2004 Jun 1
43 15169881 Molecular dissection of 2B4 signaling: implications for signal transduction by SLAM-related receptors. 2004 Jun 1
44 15182247 Distinct functions of Vav1 in JNK1 activation in Jurkat T cells versus non-haematopoietic cells. 2004 Jun 2
45 15249579 Vav GEFs are required for beta2 integrin-dependent functions of neutrophils. 2004 Jul 19 1
46 15269224 Regulation of SHP-1 tyrosine phosphatase in human platelets by serine phosphorylation at its C terminus. 2004 Sep 24 2
47 15456756 Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen. 2004 Dec 24 2
48 12626562 Proline-rich tyrosine kinase 2 and Rac activation by chemokine and integrin receptors controls NK cell transendothelial migration. 2003 Mar 15 1
49 12740575 NKG2D-DAP10 triggers human NK cell-mediated killing via a Syk-independent regulatory pathway. 2003 Jun 1
50 12836616 [Lymphocytes: what is "Vav"]. 2003 Feb 1