Cholesterol

ATP-binding cassette, sub-family A (ABC1), member 1 ; Mus musculus







499 Article(s)
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1 33538785 Krüppel-like factor 14 deletion in myeloid cells accelerates atherosclerotic lesion development. 2022 Jan 29 3
2 34744007 Amyloid beta increases ABCA1 and HMGCR protein expression, and cholesterol synthesis and accumulation in mice neurons and astrocytes. 2022 Jan 6
3 34852642 Macrophage-Specific IGF-1 Overexpression Reduces CXCL12 Chemokine Levels and Suppresses Atherosclerotic Burden in Apoe-Deficient Mice. 2022 Feb 2
4 34954451 Cholesterol and saturated fatty acids synergistically promote the malignant progression of prostate cancer. 2022 Feb 1
5 35121827 Ferredoxin reductase and p53 are necessary for lipid homeostasis and tumor suppression through the ABCA1-SREBP pathway. 2022 Mar 1
6 35139174 Circulating primitive murine erythroblasts undergo complex proteomic and metabolomic changes during terminal maturation. 2022 May 24 1
7 35207485 Daeshiho-tang Attenuates Atherosclerosis by Regulating Cholesterol Metabolism and Inducing M2 Macrophage Polarization. 2022 Jan 28 1
8 35530134 Remembering your A, B, C's: Alzheimer's disease and ABCA1. 2022 Mar 2
9 35572941 Post-Stroke Administration of L-4F Promotes Neurovascular and White Matter Remodeling in Type-2 Diabetic Stroke Mice. 2022 2
10 35586340 PCSK9 Contributes to the Cholesterol, Glucose, and Insulin2 Homeostasis in Seminiferous Tubules and Maintenance of Immunotolerance in Testis. 2022 1
11 32968199 Thrombin-Par1 signaling axis disrupts COP9 signalosome subunit 3-mediated ABCA1 stabilization in inducing foam cell formation and atherogenesis. 2021 Feb 4
12 33035679 Myocardin suppression increases lipid retention and atherosclerosis via downregulation of ABCA1 in vascular smooth muscle cells. 2021 Apr 1
13 33165140 Astragalin Retards Atherosclerosis by Promoting Cholesterol Efflux and Inhibiting the Inflammatory Response via Upregulating ABCA1 and ABCG1 Expression in Macrophages. 2021 Feb 1 1
14 33334519 Methyl tertiary-butyl ether inhibits THP-1 macrophage cholesterol efflux in vitro and accelerates atherosclerosis in ApoE-deficient mice in vivo. 2021 Mar 1
15 33441025 E17241 as a Novel ABCA1 (ATP-Binding Cassette Transporter A1) Upregulator Ameliorates Atherosclerosis in Mice. 2021 Jun 3
16 33495342 Loss of hepatic miR-33 improves metabolic homeostasis and liver function without altering body weight or atherosclerosis. 2021 Feb 2 1
17 33578049 Long non-coding RNA PCA3 inhibits lipid accumulation and atherosclerosis through the miR-140-5p/RFX7/ABCA1 axis. 2021 May 2
18 33615168 Discovery of Nonlipogenic ABCA1 Inducing Compounds with Potential in Alzheimer's Disease and Type 2 Diabetes. 2021 Feb 12 1
19 33650825 Impact of Methyl-β-Cyclodextrin and Apolipoprotein A-I on The Expression of ATP-Binding Cassette Transporter A1 and Cholesterol Depletion in C57BL/6 Mice Astrocytes. 2021 Apr 1
20 33692340 CTRP12 ameliorates atherosclerosis by promoting cholesterol efflux and inhibiting inflammatory response via the miR-155-5p/LXRα pathway. 2021 Mar 10 2
21 33744470 Targeting of miR-33 ameliorates phenotypes linked to age-related macular degeneration. 2021 Jul 7 1
22 33792344 Low LAL (Lysosomal Acid Lipase) Expression by Smooth Muscle Cells Relative to Macrophages as a Mechanism for Arterial Foam Cell Formation. 2021 Jun 1
23 33881166 MOVAS Cells: A Versatile Cell Line for Studying Vascular Smooth Muscle Cell Cholesterol Metabolism. 2021 Jul 1
24 33890787 Four Citrus Flavanones Exert Atherosclerosis Alleviation Effects in ApoE-/- Mice via Different Metabolic and Signaling Pathways. 2021 May 5 1
25 33895158 An octimibate derivative, Oxa17, enhances cholesterol efflux and exerts anti-inflammatory and atheroprotective effects in experimental atherosclerosis. 2021 Jun 1
26 33932607 Yin-xing-tong-mai decoction attenuates atherosclerosis via activating PPARγ-LXRα-ABCA1/ABCG1 pathway. 2021 Jul 3
27 33935654 Striatal Dopamine Transporter Function Is Facilitated by Converging Biology of α-Synuclein and Cholesterol. 2021 1
28 33970188 Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain. 2021 Jul 5 1
29 33994201 TIGAR mitigates atherosclerosis by promoting cholesterol efflux from macrophages. 2021 Jun 1
30 33996813 circDENND1B Participates in the Antiatherosclerotic Effect of IL-1β Monoclonal Antibody in Mouse by Promoting Cholesterol Efflux via miR-17-5p/Abca1 Axis. 2021 1
31 34084908 Regulation of microRNA-33, SREBP and ABCA1 genes in a mouse model of high cholesterol. 2021 1
32 34341345 Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease. 2021 Aug 2 3
33 34383982 Loss of Nfat5 promotes lipid accumulation in vascular smooth muscle cells. 2021 Sep 2
34 34461308 Hormone-sensitive lipase deficiency affects the expression of SR-BI, LDLr, and ABCA1 receptors/transporters involved in cellular cholesterol uptake and efflux and disturbs fertility in mouse testis. 2021 Dec 3
35 34564456 Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells. 2021 Sep 18 1
36 34660746 Role of PCSK9 in Homocysteine-Accelerated Lipid Accumulation in Macrophages and Atherosclerosis in ApoE-/- Mice. 2021 3
37 34686657 Smooth muscle 22 alpha protein inhibits VSMC foam cell formation by supporting normal LXRα signaling, ameliorating atherosclerosis. 2021 Oct 22 1
38 34753029 Qing-Xue-Xiao-Zhi formula attenuates atherosclerosis by inhibiting macrophage lipid accumulation and inflammatory response via TLR4/MyD88/NF-κB pathway regulation. 2021 Dec 2
39 34808137 AICAR upregulates ABCA1/ABCG1 expression in the retinal pigment epithelium and reduces Bruch's membrane lipid deposit in ApoE deficient mice. 2021 Dec 1
40 34831289 Deletion of TSPO Causes Dysregulation of Cholesterol Metabolism in Mouse Retina. 2021 Nov 7 1
41 34853267 Comparison of the Physical Characteristics and Behavior in ABC Transporter A1, A7 or Apolipoprotein E Knockout Mice with Lipid Transport Dysfunction. 2021 1
42 34854376 Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation. 2021 Dec 2 2
43 31423535 Ovarian cholesterol efflux: ATP-binding cassette transporters and follicular fluid HDL regulate cholesterol content in mouse oocytes†. 2020 Feb 14 1
44 31672574 Contrasting effects of membrane enrichment with polyunsaturated fatty acids on phospholipid composition and cholesterol efflux from cholesterol-loaded J774 mouse or primary human macrophages. 2020 Feb 4
45 31678514 Wnt5a/Ror2 pathway contributes to the regulation of cholesterol homeostasis and inflammatory response in atherosclerosis. 2020 Feb 2
46 31678621 Angiopoietin-1 aggravates atherosclerosis by inhibiting cholesterol efflux and promoting inflammatory response. 2020 Feb 1
47 31769014 Butyrate protects against high-fat diet-induced atherosclerosis via up-regulating ABCA1 expression in apolipoprotein E-deficiency mice. 2020 Apr 1
48 31771811 Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression. 2020 Jan 1
49 31801669 Polychlorinated biphenyl quinone promotes macrophage polarization to CD163+ cells through Nrf2 signaling pathway. 2020 Feb 2
50 31830648 Knockdown of GAS5 Inhibits Atherosclerosis Progression via Reducing EZH2-Mediated ABCA1 Transcription in ApoE-/- Mice. 2020 Mar 6 1