Title : E17241 as a Novel ABCA1 (ATP-Binding Cassette Transporter A1) Upregulator Ameliorates Atherosclerosis in Mice.

Pub. Date : 2021 Jun

PMID : 33441025






3 Functional Relationships(s)
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1 In this study, we propose a new small molecule, E17241, that may be used to treat atherosclerosis by promoting reverse cholesterol transport via ABCA1 (ATP-binding cassette transporter A1) upregulation. Cholesterol ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus
2 In this study, we propose a new small molecule, E17241, that may be used to treat atherosclerosis by promoting reverse cholesterol transport via ABCA1 (ATP-binding cassette transporter A1) upregulation. Cholesterol ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus
3 It promotes cholesterol efflux to apo AI in macrophage cells, and this effect depends on ABCA1. Cholesterol ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus