N-(1-((4-(2-(((2,4-dichlorophenyl)sulfonyl)amino)-3-hydroxypropanoyl)-1-piperazinyl)carbonyl)-3-methylbutyl)-1-benzothiophene-2-carboxamide

transient receptor potential cation channel, subfamily V, member 4 ; Mus musculus







57 Article(s)
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1 34415059 Involvement of TRPV4 in changes in rapidly inactivating potassium channels in the early stage of pilocarpine-induced status epilepticus in mice. 2022 Jan 1
2 35183536 Mechanosensitive modulation of peristaltic contractions in the mouse renal pelvis. 2022 Apr 5 1
3 35431940 Dexmedetomidine Alleviates Intracerebral Hemorrhage-Induced Anxiety-Like Behaviors in Mice Through the Inhibition of TRPV4 Opening. 2022 1
4 35439615 Blockage of transient receptor potential vanilloid 4 prevents postoperative atrial fibrillation by inhibiting NLRP3-inflammasome in sterile pericarditis mice. 2022 Jun 4
5 33393091 Transient receptor potential vanilloid 4 activation inhibits the delayed rectifier potassium channels in hippocampal pyramidal neurons: An implication in pathological changes following pilocarpine-induced status epilepticus. 2021 Mar 2
6 33449852 Transient receptor potential vanilloid 4 channel participates in mouse ventricular electrical activity. 2021 Mar 1 5
7 33715198 5,6-dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic acid accelerates the healing of colitis by inhibiting transient receptor potential vanilloid 4-mediated signaling. 2021 Apr 1
8 34427363 Transient receptor potential vanilloid 4 as a regulator of induced pluripotent stem cell chondrogenesis. 2021 Nov 1
9 34628110 Activation of transient receptor potential vanilloid 4 exacerbates myocardial ischemia-reperfusion injury via JNK-CaMKII phosphorylation pathway in isolated mice hearts. 2021 Dec 1
10 34673834 TRPV4 is activated by mechanical stimulation to induce prostaglandins release in trabecular meshwork, lowering intraocular pressure. 2021 1
11 34884463 Regulation of the Membrane Trafficking of the Mechanosensitive Ion Channels TRPV1 and TRPV4 by Zonular Tension, Osmotic Stress and Activators in the Mouse Lens. 2021 Nov 23 1
12 34917777 Positive modulation of the TMEM16B mediated currents by TRPV4 antagonist. 2021 Dec 1
13 32271891 Polymodal Sensory Transduction in Mouse Corneal Epithelial Cells. 2020 Apr 9 1
14 32542737 Transient stimulation of TRPV4-expressing keratinocytes promotes hair follicle regeneration in mice. 2020 Sep 1
15 32736678 Transient receptor potential vanilloid 4 agonist GSK1016790A improves neurological outcomes after intracerebral hemorrhage in mice. 2020 Aug 27 2
16 32931478 TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema. 2020 Oct 15 2
17 32980513 Synthesis and in vitro evaluation of new TRPV4 ligands and biodistribution study of an 11C-labeled radiotracer in rodents. 2020 Nov 15 1
18 31097691 TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice. 2019 May 16 4
19 31299321 Transient receptor potential vanilloid 4 is involved in the upregulation of connexin expression following pilocarpine-induced status epilepticus in mice. 2019 Oct 1
20 31603369 Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced relaxations and nitric oxide production in mesenteric arteries: comparative study using wild-type and TRPC1-/- mice. 2019 Dec 1
21 31801932 Pharmacological Inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Alleviates Carbon Tetrachloride-Induced Liver Fibrosis in Mice. 2019 2
22 29053877 Transient receptor potential vanilloid 4 channel regulates vascular endothelial permeability during colonic inflammation in dextran sulphate sodium-induced murine colitis. 2018 Jan 2
23 29109190 TRPV4 (Transient Receptor Potential Vanilloid 4) Mediates Endothelium-Dependent Contractions in the Aortas of Hypertensive Mice. 2018 Jan 2
24 29187363 TRPV4 heats up ANO1-dependent exocrine gland fluid secretion. 2018 Apr 1
25 29439248 Transient Receptor Potential Vanilloid 4 Activation-Induced Increase in Glycine-Activated Current in Mouse Hippocampal Pyramidal Neurons. 2018 1
26 29701904 TRPV4 activates cytosolic phospholipase A2 via Ca2+ -dependent PKC/ERK1/2 signalling in controlling hypertensive contraction. 2018 Apr 27 1
27 30118343 Mineralocorticoid receptor antagonism improves parenchymal arteriole dilation via a TRPV4-dependent mechanism and prevents cognitive dysfunction in hypertension. 2018 Nov 1 1
28 30298837 [TRPV4 regulates vascular endothelial permeability during colonic inflammation in dextran sulphate sodium-induced murine colitis]. 2018 3
29 30365528 Involvement of VNUT-exocytosis in transient receptor potential vanilloid 4-dependent ATP release from gastrointestinal epithelium. 2018 3
30 30386208 Polymodal TRPV1 and TRPV4 Sensors Colocalize but Do Not Functionally Interact in a Subpopulation of Mouse Retinal Ganglion Cells. 2018 1
31 27660267 Activation of Transient Receptor Potential Vanilloid 4 Promotes the Proliferation of Stem Cells in the Adult Hippocampal Dentate Gyrus. 2017 Oct 1
32 28612138 Transient receptor potential vanilloid 4 (TRPV4) channel as a target of crotamiton and its bimodal effects. 2017 Oct 1
33 28663724 Activation of Transient Receptor Potential Vanilloid 4 Impairs the Dendritic Arborization of Newborn Neurons in the Hippocampal Dentate Gyrus through the AMPK and Akt Signaling Pathways. 2017 2
34 28947806 Premature contractions of the bladder are suppressed by interactions between TRPV4 and SK3 channels in murine detrusor PDGFRα+ cells. 2017 Sep 25 2
35 25399955 Activation of Transient Receptor Potential Vanilloid 4 is Involved in Neuronal Injury in Middle Cerebral Artery Occlusion in Mice. 2016 Jan 1
36 25867067 Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy. 2016 Jan 21 1
37 27191895 A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis. 2016 Jun 21 1
38 27350729 Transient receptor potential vanilloid 4-dependent calcium influx and ATP release in mouse and rat gastric epithelia. 2016 Jun 28 2
39 27779758 TRPV4 participates in pressure-induced inhibition of renin secretion by juxtaglomerular cells. 2016 Dec 15 1
40 25069877 Functional transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 channels along different segments of the renal vasculature. 2015 Feb 2
41 25529150 Molecular and functional characterization of TRPV4 channels in pregnant and nonpregnant mouse uterus. 2015 Feb 1 2
42 25914628 Blockage of transient receptor potential vanilloid 4 inhibits brain edema in middle cerebral artery occlusion mice. 2015 1
43 26006045 Mechanotransduction via TRPV4 regulates inflammation and differentiation in fetal mouse distal lung epithelial cells. 2015 May 27 1
44 26043075 Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling pathways. 2015 Jun 4 2
45 26064477 Blockade or deletion of transient receptor potential vanilloid 4 (TRPV4) is not protective in a murine model of sepsis. 2015 1
46 26102209 Genetic deficit of KCa 3.1 channels protects against pulmonary circulatory collapse induced by TRPV4 channel activation. 2015 Sep 2
47 26282788 Opposing actions of TRPV4 channel activation in the lung vasculature. 2015 Dec 2
48 26330151 Transient receptor potential vanilloid 4 inhibits mouse colonic motility by activating NO-dependent enteric neurotransmission. 2015 Dec 1
49 26475857 P2Y1 Receptor Activation of the TRPV4 Ion Channel Enhances Purinergic Signaling in Satellite Glial Cells. 2015 Nov 27 5
50 22928864 4α-phorbol 12,13-didecanoate activates cultured mouse dorsal root ganglia neurons independently of TRPV4. 2013 Feb 1