Title : A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis.

Pub. Date : 2016 Jun 21

PMID : 27191895






1 Functional Relationships(s)
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1 We found that GSK1016790A, a potent and specific small-molecule agonist of TRPV4, induces the phosphorylation and activation of eNOS partially through the AMPK pathway. N-(1-((4-(2-(((2,4-dichlorophenyl)sulfonyl)amino)-3-hydroxypropanoyl)-1-piperazinyl)carbonyl)-3-methylbutyl)-1-benzothiophene-2-carboxamide transient receptor potential cation channel, subfamily V, member 4 Mus musculus