Glycine

glutamate ionotropic receptor NMDA type subunit 2B ; Homo sapiens







47 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34201404 Purinergic-Glycinergic Interaction in Neurodegenerative and Neuroinflammatory Disorders of the Retina. 2021 Jun 8 3
2 34212862 Two de novo GluN2B mutations affect multiple NMDAR-functions and instigate severe pediatric encephalopathy. 2021 Jul 2 1
3 34321660 Structural basis of ketamine action on human NMDA receptors. 2021 Aug 1
4 32194228 Differential Roles of GluN2B in Two Types of Chemical-induced Long Term Potentiation-mediated Phosphorylation Regulation of GluA1 at Serine 845 in Hippocampal Slices. 2020 May 1 1
5 33122756 The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors. 2020 Oct 29 1
6 31302238 Glycine transporter inhibitors: A new avenue for managing neuropathic pain. 2019 Oct 1
7 29681798 The LILI Motif of M3-S2 Linkers Is a Component of the NMDA Receptor Channel Gate. 2018 1
8 29966365 NR1 and NR3B Composed Intranuclear N-methyl-d-aspartate Receptor Complexes in Human Melanoma Cells. 2018 Jun 30 1
9 30168177 The GluN2B-Glu413Gly NMDA receptor variant arising from a de novo GRIN2B mutation promotes ligand-unbinding and domain opening. 2018 Dec 1
10 28749574 Design, Synthesis, Pharmacological Evaluation and Docking Studies of GluN2B-Selective NMDA Receptor Antagonists with a Benzo[7]annulen-7-amine Scaffold. 2017 Aug 8 1
11 26577016 Disruption of S2-M4 linker coupling reveals novel subunit-specific contributions to N-methyl-d-aspartate receptor function and ethanol sensitivity. 2016 Jun 1
12 27010645 Intersubunit interactions at putative sites of ethanol action in the M3 and M4 domains of the NMDA receptor GluN1 and GluN2B subunits. 2016 Jun 3
13 26086092 Spermidine and Ca(2+), but not Na(+), can permeate NMDA receptors consisting of GluN1 and GluN2A or GluN2B in the presence of Mg(2+). 2015 Aug 7 1
14 23089362 Role of nonsynaptic GluN2B-containing NMDA receptors in excitotoxicity: evidence that fluoxetine selectively inhibits these receptors and may have neuroprotective effects. 2013 Apr 1
15 23627311 Synthesis and structure activity relationship of tetrahydroisoquinoline-based potentiators of GluN2C and GluN2D containing N-methyl-D-aspartate receptors. 2013 Jul 11 1
16 23962100 Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis: an etiology worth considering in the differential diagnosis of delirium. 2013 Sep-Oct 1
17 22610100 Cleavage of the NR2B subunit amino terminus of N-methyl-D-aspartate (NMDA) receptor by tissue plasminogen activator: identification of the cleavage site and characterization of ifenprodil and glycine affinities on truncated NMDA receptor. 2012 Jul 20 1
18 20688135 Specific determinants of conantokins that dictate their selectivity for the NR2B subunit of N-methyl-D-aspartate receptors. 2010 Oct 27 1
19 20958962 Residues at the tip of the pore loop of NR3B-containing NMDA receptors determine Ca2+ permeability and Mg2+ block. 2010 Oct 19 3
20 19348678 Effects of NR1 splicing on NR1/NR3B-type excitatory glycine receptors. 2009 Apr 6 1
21 19726695 Expression of glycine-activated diheteromeric NR1/NR3 receptors in human embryonic kidney 293 cells Is NR1 splice variant-dependent. 2009 Dec 3
22 17959602 Formation of NR1/NR2 and NR1/NR3 heterodimers constitutes the initial step in N-methyl-D-aspartate receptor assembly. 2008 Jan 4 4
23 18272676 The activation gate and gating mechanism of the NMDA receptor. 2008 Feb 13 1
24 18636091 Molecular mechanism of ligand recognition by NR3 subtype glutamate receptors. 2008 Aug 6 1
25 18779583 Rules of engagement for NMDA receptor subunits. 2008 Sep 16 1
26 17047094 Subunit-specific roles of glycine-binding domains in activation of NR1/NR3 N-methyl-D-aspartate receptors. 2007 Jan 4
27 17050777 Comparative studies of anthraquinone- and anthracene-tetraamines as blockers of N-methyl-D-aspartate receptors. 2007 Jan 1
28 17214961 Principal role of NR3 subunits in NR1/NR3 excitatory glycine receptor function. 2007 Mar 2 4
29 17502428 Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits. 2007 Aug 1
30 17878266 The N-terminal domains of both NR1 and NR2 subunits determine allosteric Zn2+ inhibition and glycine affinity of N-methyl-D-aspartate receptors. 2007 Dec 2
31 15490133 Glycine-induced neurotoxicity in organotypic hippocampal slice cultures. 2005 Mar 1
32 14558884 Influence of a mutation in the ATP-binding region of Ca2+/calmodulin-dependent protein kinase II on its interaction with peptide substrates. 2004 Mar 1 2
33 15262068 Kinetic characterization of novel NR2B antagonists using fluorescence detection of calcium flux. 2004 Aug 30 1
34 22812023 N-[2-(N-(2-mercaptoethyl)) amino ethyl]-N-(2-mercaptoethyl)-3,5-dimethylacetamide amantadine-technetium 2004 1
35 11572853 Ethanol inhibition of N-methyl-D-aspartate receptors is reduced by site-directed mutagenesis of a transmembrane domain phenylalanine residue. 2001 Nov 30 1
36 10780999 Characterization of the binding of two novel glycine site antagonists to cloned NMDA receptors: evidence for two pharmacological classes of antagonists. 2000 May 1
37 10206186 Ethanol sensitivity of NMDA receptor function in developing cerebellar granule neurons. 1999 Mar 19 1
38 10208572 NR2B-containing NMDA receptors are up-regulated in temporal cortex in schizophrenia. 1999 Feb 25 2
39 9489750 Functional characterization of human N-methyl-D-aspartate subtype 1A/2D receptors. 1998 Mar 1
40 9312102 The NR2B-specific interactions of polyamines and protons with the N-methyl-D-aspartate receptor. 1997 Oct 3 2
41 9375665 Effects of acute and chronic ethanol exposure on heteromeric N-methyl-D-aspartate receptors expressed in HEK 293 cells. 1997 Dec 2
42 8632186 Modulation of 45Ca2+ influx into cells stably expressing recombinant human NMDA receptors by ligands acting at distinct recognition sites. 1996 Jun 1
43 8768735 Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors. 1996 Aug 1
44 8859015 Stable expression and characterization of recombinant human heteromeric N-methyl-D-aspartate receptor subtypes NMDAR1A/2A and NMDAR1A/2B in mammalian cells. 1996 Oct 1
45 7476914 Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells. 1995 Nov 1
46 8613724 Excitotoxic cell death and delayed rescue in human neurons derived from NT2 cells. 1995 Dec 1
47 7528680 Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition. 1994 Aug 16 1