Title : The N-terminal domains of both NR1 and NR2 subunits determine allosteric Zn2+ inhibition and glycine affinity of N-methyl-D-aspartate receptors.

Pub. Date : 2007 Dec

PMID : 17878266






2 Functional Relationships(s)
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1 Furthermore, by replacing the NR2A-NTD with the NR2B NTD, and vice versa, the different glycine affinities of NR1/NR2A and NR1/NR2B receptors were found to be determined by their respective NR2-NTDs. Glycine glutamate ionotropic receptor NMDA type subunit 2B Homo sapiens
2 Furthermore, by replacing the NR2A-NTD with the NR2B NTD, and vice versa, the different glycine affinities of NR1/NR2A and NR1/NR2B receptors were found to be determined by their respective NR2-NTDs. Glycine glutamate ionotropic receptor NMDA type subunit 2B Homo sapiens