| 1 |
35016033 | Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses. | 2022 Feb 3 |
2 |
| 2 |
34023736 | Cyclic mimetics of kinase-inhibitory region of Suppressors of Cytokine Signaling 1: Progress toward novel anti-inflammatory therapeutics. | 2021 Oct 5 |
1 |
| 3 |
34118143 | Baicalein modulates the radiosensitivity of cervical cancer cells in vitro via miR-183 and the JAK2/STAT3 signaling pathway. | 2021 Jul |
2 |
| 4 |
34290255 | Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer. | 2021 Jul 21 |
1 |
| 5 |
34699606 | Zinc induces reactive astrogliosis through ERK-dependent activation of Stat3 and promotes synaptic degeneration. | 2021 Dec |
2 |
| 6 |
31848046 | T618I CSF3R mutations in chronic neutrophilic leukemia induce oncogenic signals through aberrant trafficking and constitutive phosphorylation of the O-glycosylated receptor form. | 2020 Feb 26 |
2 |
| 7 |
31901221 | A Comprehensive Tyrosine Phosphoproteomic Analysis Reveals Novel Components of the Platelet CLEC-2 Signaling Cascade. | 2020 Feb |
1 |
| 8 |
32213463 | Renin Promotes STAT4 Phosphorylation to Induce IL-17 Production in Keratinocytes of Oral Lichen Planus. | 2020 Apr 24 |
1 |
| 9 |
32232334 | PHB regulates meiotic recombination via JAK2-mediated histone modifications in spermatogenesis. | 2020 May 21 |
1 |
| 10 |
33193390 | SOCS, Intrinsic Virulence Factors, and Treatment of COVID-19. | 2020 |
1 |
| 11 |
30872773 | Renal expression of JAK2 is high in polycystic kidney disease and its inhibition reduces cystogenesis. | 2019 Mar 14 |
1 |
| 12 |
30944118 | Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis. | 2019 Jun |
1 |
| 13 |
31255914 | Tyrosine-phosphorylated SOCS3 negatively regulates cellular transformation mediated by the myeloproliferative neoplasm-associated JAK2 V617F mutant. | 2019 Nov |
1 |
| 14 |
31336247 | Identification of a distinct subset of disease-associated gain-of-function missense mutations in the STAT1 coiled-coil domain as system mutants. | 2019 Oct |
2 |
| 15 |
31540495 | Interleukin4Rα (IL4Rα) and IL13Rα1 Are Associated with the Progress of Renal Cell Carcinoma through Janus Kinase 2 (JAK2)/Forkhead Box O3 (FOXO3) Pathways. | 2019 Sep 18 |
1 |
| 16 |
31549971 | The role of JAK inhibitors in multiple myeloma. | 2019 Sep |
1 |
| 17 |
31725895 | The pan-PIM inhibitor INCB053914 displays potent synergy in combination with ruxolitinib in models of MPN. | 2019 Nov 26 |
1 |
| 18 |
31870101 | JAK2 and Beyond: Mutational Study of JAK2V617 in Myeloproliferative Disorders and Haematological Malignancies in Kashmiri population. | 2019 Dec 1 |
1 |
| 19 |
29127727 | Diversity in peptide recognition by the SH2 domain of SH2B1. | 2018 Feb |
1 |
| 20 |
29761158 | Phase II study of ruxolitinib, a selective JAK1/2 inhibitor, in patients with metastatic triple-negative breast cancer. | 2018 |
1 |
| 21 |
30048621 | A cell penetrating peptide from SOCS-1 prevents ocular damage in experimental autoimmune uveitis. | 2018 Dec |
1 |
| 22 |
30377265 | KDM3A histone demethylase functions as an essential factor for activation of JAK2-STAT3 signaling pathway. | 2018 Nov 13 |
1 |
| 23 |
30416684 | CXCR4- and BCR-triggered integrin activation in B-cell chronic lymphocytic leukemia cells depends on JAK2-activated Bruton's tyrosine kinase. | 2018 Oct 12 |
1 |
| 24 |
27998978 | Three Tyrosine Residues in the Erythropoietin Receptor Are Essential for Janus Kinase 2 V617F Mutant-induced Tumorigenesis. | 2017 Feb 3 |
9 |
| 25 |
28031410 | Nuclear Import of JAK1 Is Mediated by a Classical NLS and Is Required for Survival of Diffuse Large B-cell Lymphoma. | 2017 Mar |
2 |
| 26 |
28365441 | The multi-site docking protein Gab1 is constitutively phosphorylated independent from its recruitment to the plasma membrane in Jak2-V617F-positive cells and mediates proliferation of human erythroleukaemia cells. | 2017 Jul |
1 |
| 27 |
28427901 | The 20kDa and 22kDa forms of human growth hormone (hGH) exhibit different intracellular signalling profiles and properties. | 2017 Jul 1 |
1 |
| 28 |
28634059 | A pumpkin polysaccharide induces apoptosis by inhibiting the JAK2/STAT3 pathway in human hepatoma HepG2 cells. | 2017 Nov |
2 |
| 29 |
28722170 | Activation of the B-cell receptor successively activates NF-κB and STAT3 in chronic lymphocytic leukemia cells. | 2017 Nov 15 |
2 |
| 30 |
29168692 | Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth. | 2017 Nov 23 |
3 |
| 31 |
26508024 | Epigenetic regulation and anti-tumorigenic effects of SH2-containing protein tyrosine phosphatase 1 (SHP1) in human gastric cancer cells. | 2016 Apr |
3 |
| 32 |
27542844 | Prolactin-induced PAK1 tyrosyl phosphorylation promotes FAK dephosphorylation, breast cancer cell motility, invasion and metastasis. | 2016 Aug 20 |
1 |
| 33 |
30695496 | [THE BRAIN LEPTIN SIGNALING SYSTEM AND ITS FUNCTIONAL STATE IN METABOLIC SYNDROME AND TYPE 2 DIABETES MELLITIS]. | 2016 Mar |
1 |
| 34 |
25466889 | Phosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnover. | 2015 Mar |
3 |
| 35 |
25954276 | SOCS1 Mimetics and Antagonists: A Complementary Approach to Positive and Negative Regulation of Immune Function. | 2015 |
2 |
| 36 |
26288682 | Structure-Based Design of Selective Janus Kinase 2 Imidazo[4,5-d]pyrrolo[2,3-b]pyridine Inhibitors. | 2015 Aug 13 |
1 |
| 37 |
24890449 | Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Src‑mediated phosphorylation of EGF receptor tyrosine kinase. | 2014 Aug |
1 |
| 38 |
24930769 | Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation. | 2014 May 30 |
1 |
| 39 |
24941337 | S-Glutathionylation at Cys328 and Cys542 impairs STAT3 phosphorylation. | 2014 Aug 15 |
1 |
| 40 |
25072659 | Hyperglycemia and angiotensin II cooperate to enhance collagen I deposition by cardiac fibroblasts through a ROS-STAT3-dependent mechanism. | 2014 Nov |
2 |
| 41 |
23110939 | Type I IFN receptor controls activated TYK2 in the nucleus: implications for EAE therapy. | 2013 Jan 15 |
1 |
| 42 |
23236554 | JAK kinases are required for the bacterial RNA and poly I:C induced tyrosine phosphorylation of PKR. | 2013 |
1 |
| 43 |
23313376 | Pterostilbene exerts antitumor activity against human osteosarcoma cells by inhibiting the JAK2/STAT3 signaling pathway. | 2013 Feb 8 |
1 |
| 44 |
23340249 | Tyrosyl phosphorylated PAK1 regulates breast cancer cell motility in response to prolactin through filamin A. | 2013 Mar |
5 |
| 45 |
23583449 | A crucial role for Lyn in TIMP-1 erythroid cell survival signalling pathway. | 2013 May 21 |
1 |
| 46 |
24030252 | IGF-1R modulation of acute GH-induced STAT5 signaling: role of protein tyrosine phosphatase activity. | 2013 Nov |
1 |
| 47 |
24069558 | JAK2-V617F-induced MAPK activity is regulated by PI3K and acts synergistically with PI3K on the proliferation of JAK2-V617F-positive cells. | 2013 Jul 1 |
1 |
| 48 |
22222369 | Nuclear localization of lymphocyte-specific protein tyrosine kinase (Lck) and its role in regulating LIM domain only 2 (Lmo2) gene. | 2012 Jan 20 |
1 |
| 49 |
22528658 | Structural basis of interleukin-5 dimer recognition by its α receptor. | 2012 Jun |
1 |
| 50 |
22580455 | Regulation of p27 (Kip1) by mitogen-induced tyrosine phosphorylation. | 2012 May 15 |
1 |