Pub. Date : 2016 Mar
PMID : 30695496
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | This leads to activation of tyrosine kinase JAK2, which phosphory- lates tyrosine-containing sites located in the cytoplasmic domain of the receptor, resulting in stimulation of activity of phosphatidylinositol-3-kinase, the transcription factors STAT3 and STAT5, phosphatase SHP2, and mitogen-activated protein kinase. | Tyrosine | Janus kinase 2 | Homo sapiens |