Paclitaxel

MDM2 proto-oncogene ; Homo sapiens







12 Article(s)
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1 33771522 MiR-221-3p-mediated downregulation of MDM2 reverses the paclitaxel resistance of non-small cell lung cancer in vitro and in vivo. 2021 May 15 4
2 34799910 P1-39: Paclitaxel induces growth inhibition in gefitinib-resistant PC9-MET cells by downregulating MDM2 and activating p53. 2021 Nov 1
3 30774764 Downregulation of miR-194-5p induces paclitaxel resistance in ovarian cancer cells by altering MDM2 expression. 2019 Jan 18 6
4 26799187 p38 MAPK-induced MDM2 degradation confers paclitaxel resistance through p53-mediated regulation of EGFR in human lung cancer cells. 2016 Feb 16 1
5 27659528 Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway. 2016 Nov 8 1
6 25022573 MDM2 molecular imaging for the prediction of chemotherapeutic sensitivity in human breast cancer xenograft. 2014 1
7 21556366 Predictive and prognostic impact of TP53 mutations and MDM2 promoter genotype in primary breast cancer patients treated with epirubicin or paclitaxel. 2011 Apr 27 3
8 22701761 Human Oncoprotein MDM2 Up-regulates Expression of NF-κB2 Precursor p100 Conferring a Survival Advantage to Lung Cells. 2011 Oct 1
9 19918798 Paclitaxel and beta-lapachone synergistically induce apoptosis in human retinoblastoma Y79 cells by downregulating the levels of phospho-Akt. 2010 Feb 3
10 18813780 Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1. 2008 Oct 1
11 13130078 Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation, apoptosis, multiple gene expression, and chemotherapy. 2003 Sep 30 2
12 11025661 p53 is associated with cellular microtubules and is transported to the nucleus by dynein. 2000 Oct 1