Serine

signal transducer and activator of transcription 3 ; Mus musculus







55 Article(s)
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1 33788814 Hepatocyte growth factor induces pErk and pSTAT3 (Ser 727) to promote mitochondrial activity and neurite outgrowth in primary dorsal root ganglion cultures. 2021 Apr 7 2
2 34974065 A mitochondrial STAT3-methionine metabolism axis promotes ILC2-driven allergic lung inflammation. 2021 Dec 30 2
3 31309353 Pharmacological preconditioning with phosphodiestrase inhibitor: an answer to stem cell survival against ischemic injury through JAK/STAT signaling. 2020 Mar 1
4 32200265 STAT3-driven hematopoiesis and lymphopoiesis abnormalities are dependent on serine phosphorylation. 2020 Mar 19 3
5 32732870 STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression. 2020 Jul 30 1
6 30993885 Role of Jagged1/STAT3 signalling in platinum-resistant ovarian cancer. 2019 Jun 3
7 30994173 Phospho-valproic acid (MDC-1112) suppresses glioblastoma growth in preclinical models through the inhibition of STAT3 phosphorylation. 2019 Dec 31 3
8 31022374 Critical appraisal of STAT3 pattern in adult cardiomyocytes. 2019 Jun 4
9 29683527 Modulation of allergic responses by mitochondrial STAT3 inhibitors. 2018 Nov 1
10 29074644 Extracellular Signal-Regulated Kinase 1/2 Regulates Mouse Kidney Injury Molecule-1 Expression Physiologically and Following Ischemic and Septic Renal Injury. 2017 Dec 2
11 27018293 Hes3 expression in the adult mouse brain is regulated during demyelination and remyelination. 2016 Jul 1 1
12 26198700 Cyclin-dependent kinase 5 represses Foxp3 gene expression and Treg development through specific phosphorylation of Stat3 at Serine 727. 2015 Oct 4
13 26573296 Insulin-InsR signaling drives multipotent progenitor differentiation toward lymphoid lineages. 2015 Dec 14 1
14 22911886 Serine 727 phosphorylation of STAT3: an early change in mouse hepatocarcinogenesis induced by neonatal treatment with diethylnitrosamine. 2014 Jan 1
15 24302476 STAT3 phosphorylation at tyrosine 705 and serine 727 differentially regulates mouse ESC fates. 2014 May 1
16 24819473 Biologically active leptin-related synthetic peptides activate STAT3 via phosphorylation of ERK1/2 and PI-3K. 2014 Jul 5
17 24850910 Angiotensin II and canonical transient receptor potential-6 activation stimulate release of a signal transducer and activator of transcription 3-activating factor from mouse podocytes. 2014 Aug 1
18 24922005 Antitumor efficacy of the anti-interleukin-6 (IL-6) antibody siltuximab in mouse xenograft models of lung cancer. 2014 Jul 1
19 25150294 STAT3 supports experimental K-RasG12D-induced murine myeloproliferative neoplasms dependent on serine phosphorylation. 2014 Oct 2 2
20 25301019 Mouse neutrophils express functional umami taste receptor T1R1/T1R3. 2014 Nov 1
21 22875246 Rapamycin inhibits both motility through down-regulation of p-STAT3 (S727) by disrupting the mTORC2 assembly and peritoneal dissemination in sarcomatoid cholangiocarcinoma. 2013 Feb 1
22 23364341 Role of STAT3 in angiotensin II-induced hypertension and cardiac remodeling revealed by mice lacking STAT3 serine 727 phosphorylation. 2013 Jun 1
23 23376140 Hepatocytes display a compensatory survival response against cadmium toxicity by a mechanism mediated by EGFR and Src. 2013 Apr 1
24 23665018 AG490 inhibits NFATc1 expression and STAT3 activation during RANKL induced osteoclastogenesis. 2013 Jun 14 1
25 23693126 Inhibition of a novel specific neuroglial integrin signaling pathway increases STAT3-mediated CNTF expression. 2013 May 21 1
26 24019511 Mitochondrial localized Stat3 promotes breast cancer growth via phosphorylation of serine 727. 2013 Oct 25 1
27 22179221 The peroxisome proliferator-activated receptor (PPAR) β/δ agonist GW501516 inhibits IL-6-induced signal transducer and activator of transcription 3 (STAT3) activation and insulin resistance in human liver cells. 2012 Mar 1
28 22268811 α(1A)-adrenergic receptor differentially regulates STAT3 phosphorylation through PKCϵ and PKCδ in myocytes. 2012 Apr 3
29 22619361 Hepatic Src homology phosphatase 2 regulates energy balance in mice. 2012 Jul 1
30 23904970 Differential STAT3 signaling in the heart: Impact of concurrent signals and oxidative stress. 2012 Apr 1 1
31 21467030 Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein. 2011 Jun 3 1
32 21617181 Activation of peroxisome proliferator-activated receptor-β/-δ (PPAR-β/-δ) ameliorates insulin signaling and reduces SOCS3 levels by inhibiting STAT3 in interleukin-6-stimulated adipocytes. 2011 Jul 2
33 22110749 Capric acid inhibits NO production and STAT3 activation during LPS-induced osteoclastogenesis. 2011 1
34 20124472 The neurofibromatosis type 1 tumor suppressor controls cell growth by regulating signal transducer and activator of transcription-3 activity in vitro and in vivo. 2010 Feb 15 2
35 20595392 Role of NEK6 in tumor promoter-induced transformation in JB6 C141 mouse skin epidermal cells. 2010 Sep 3 5
36 19131594 Function of mitochondrial Stat3 in cellular respiration. 2009 Feb 6 2
37 19710241 Transglutaminase-1 protects renal epithelial cells from hydrogen peroxide-induced apoptosis through activation of STAT3 and AKT signaling pathways. 2009 Nov 1
38 18403479 Interleukin-6 inhibits receptor activator of nuclear factor kappaB ligand-induced osteoclastogenesis by diverting cells into the macrophage lineage: key role of Serine727 phosphorylation of signal transducer and activator of transcription 3. 2008 Jul 1
39 18718531 c-Jun NH(2)-terminal kinase mediates leptin-stimulated androgen-independent prostate cancer cell proliferation via signal transducer and activator of transcription 3 and Akt. 2008 Oct 5
40 18723372 Inhibition of lipopolysaccharide-induced nitric oxide synthesis by nicotine through S6K1-p42/44 MAPK pathway and STAT3 (Ser 727) phosphorylation in Raw 264.7 cells. 2008 Oct 3
41 17064687 Inhibitory effects of homeodomain-interacting protein kinase 2 on the aorta-gonad-mesonephros hematopoiesis. 2007 Jan 1 1
42 17209045 Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation. 2007 Mar 2 1
43 17583567 Protein kinase Cepsilon interacts with Stat3 and regulates its activation that is essential for the development of skin cancer. 2007 Aug 1
44 15705584 A role of STAT3 in Rho GTPase-regulated cell migration and proliferation. 2005 Apr 29 1
45 16172266 Role of the protein kinase C-epsilon-Raf-1-MEK-1/2-p44/42 MAPK signaling cascade in the activation of signal transducers and activators of transcription 1 and 3 and induction of cyclooxygenase-2 after ischemic preconditioning. 2005 Sep 27 5
46 14617800 P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. 2004 Feb 1
47 14673173 Essential role of STAT3 in postnatal survival and growth revealed by mice lacking STAT3 serine 727 phosphorylation. 2004 Jan 3
48 15096606 Cyclin-dependent kinase 5 phosphorylates signal transducer and activator of transcription 3 and regulates its transcriptional activity. 2004 Apr 27 4
49 15189833 Presence of permanently activated signal transducers and activators of transcription in nuclear interchromatin granules of unstimulated mouse oocytes and preimplantation embryos. 2004 Oct 1
50 12684046 Determination of leptin signaling pathways in human and murine keratinocytes. 2003 Apr 18 1