Tyrosine

signal transducer and activator of transcription 3 ; Mus musculus







197 Article(s)
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1 35411090 Activated Src requires Cadherin-11, Rac, and gp130 for Stat3 activation and survival of mouse Balb/c3T3 fibroblasts. 2022 Apr 11 2
2 33177649 Loss of interleukin-17 receptor D promotes chronic inflammation-associated tumorigenesis. 2021 Jan 1
3 33992648 A Targetable, Noncanonical Signal Transducer and Activator of Transcription 3 Activation Induced by the Y-Less Region of IL-22 Receptor Orchestrates Imiquimod-Induced Psoriasis-Like Dermatitis in Mice. 2021 Nov 4
4 34744770 IL-6/STAT3 Induced Neuron Apoptosis in Hypoxia by Downregulating ATF6 Expression. 2021 2
5 31309353 Pharmacological preconditioning with phosphodiestrase inhibitor: an answer to stem cell survival against ischemic injury through JAK/STAT signaling. 2020 Mar 1
6 31784187 NO-releasing STAT3 inhibitors suppress BRAF-mutant melanoma growth. 2020 Jan 15 1
7 32088220 Cucurbitacin B inhibits gastric cancer progression by suppressing STAT3 activity. 2020 May 15 1
8 32134217 Gestational exposure to valproic acid upregulates total Stat3 protein expression while downregulating phosphorylated Stat3 in CD-1 mouse embryos with neural tube defects. 2020 Apr 15 2
9 32200265 STAT3-driven hematopoiesis and lymphopoiesis abnormalities are dependent on serine phosphorylation. 2020 Mar 19 1
10 32355553 pSTAT3 Y705 is a prognostic biomarker identified from time-series gene expression profiles of a chemically induced mouse model of hepatocellular carcinoma. 2020 1
11 32476221 Miconazole inhibits signal transducer and activator of transcription 3 signaling by preventing its interaction with DNA damage-induced apoptosis suppressor. 2020 Jul 4
12 32655542 MicroRNA-200a Inhibits Inflammation and Atherosclerotic Lesion Formation by Disrupting EZH2-Mediated Methylation of STAT3. 2020 2
13 33332446 Stat3 oxidation-dependent regulation of gene expression impacts on developmental processes and involves cooperation with Hif-1α. 2020 1
14 30269370 Novel leptin receptor signaling mutants identify location and sex-dependent modulation of bone density, adiposity, and growth. 2019 Mar 1
15 30741923 Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation. 2019 Feb 11 1
16 30797070 A TCM formula comprising Sophorae Flos and Lonicerae Japonicae Flos alters compositions of immune cells and molecules of the STAT3 pathway in melanoma microenvironment. 2019 Apr 1
17 30899259 Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury. 2019 4
18 28881473 The classic signalling and trans-signalling of interleukin-6 are both injurious in podocyte under high glucose exposure. 2018 Jan 1
19 29797458 Modulation of STAT3 phosphorylation by PTPN2 inhibits naïve pluripotency of embryonic stem cells. 2018 Jul 1
20 29967195 IL (Interleukin)-10-STAT3-Galectin-3 Axis Is Essential for Osteopontin-Producing Reparative Macrophage Polarization After Myocardial Infarction. 2018 Oct 30 1
21 30283437 Aryl Hydrocarbon Receptor Promotes IL-10 Expression in Inflammatory Macrophages Through Src-STAT3 Signaling Pathway. 2018 1
22 28343944 RACK1 cooperates with NRASQ61K to promote melanoma in vivo. 2017 Aug 4
23 28579428 Biochanin A enhances RORγ activity through STAT3-mediated recruitment of NCOA1. 2017 Aug 5 2
24 28626343 Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis. 2017 2
25 28771545 Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6. 2017 1
26 26775702 Leukemia inhibitory factor (LIF) withdrawal activates mTOR signaling pathway in mouse embryonic stem cells through the MEK/ERK/TSC2 pathway. 2016 Jan 14 1
27 27267892 STAT3 as a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma. 2016 Aug 1
28 27779705 Diphenhydramine induces melanoma cell apoptosis by suppressing STAT3/MCL-1 survival signaling and retards B16-F10 melanoma growth in vivo. 2016 Dec 2
29 25108518 Regulation of rod photoreceptor differentiation by STAT3 is controlled by a tyrosine phosphatase. 2015 Jan 1
30 25143196 Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice. 2015 Feb 1
31 25335925 Pwp1 is required for the differentiation potential of mouse embryonic stem cells through regulating Stat3 signaling. 2015 Mar 1
32 25411359 STAT3 induces anoikis resistance, promotes cell invasion and metastatic potential in pancreatic cancer cells. 2015 Jan 2
33 25968579 Leukemia inhibitory factor increases glucose uptake in mouse skeletal muscle. 2015 Jul 15 1
34 26177470 S-Nitrosoglutathione-mediated STAT3 regulation in efficacy of radiotherapy and cisplatin therapy in head and neck squamous cell carcinoma. 2015 Dec 1
35 26380299 Tyrosine 705 Phosphorylation of STAT3 Is Associated with Phenotype Severity in TGFβ1 Transgenic Mice. 2015 1
36 26675719 Germline variant FGFR4  p.G388R exposes a membrane-proximal STAT3 binding site. 2015 Dec 24 3
37 24222636 Quantitative control of intracellular signaling activity through chimeric receptors incorporating multiple identical tyrosine motifs. 2014 May 1
38 24302476 STAT3 phosphorylation at tyrosine 705 and serine 727 differentially regulates mouse ESC fates. 2014 May 2
39 24508558 SN79, a sigma receptor antagonist, attenuates methamphetamine-induced astrogliosis through a blockade of OSMR/gp130 signaling and STAT3 phosphorylation. 2014 Apr 1
40 24744378 The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation. 2014 Apr 18 3
41 24819473 Biologically active leptin-related synthetic peptides activate STAT3 via phosphorylation of ERK1/2 and PI-3K. 2014 Jul 3
42 24850910 Angiotensin II and canonical transient receptor potential-6 activation stimulate release of a signal transducer and activator of transcription 3-activating factor from mouse podocytes. 2014 Aug 2
43 24887420 Preclinical therapeutic potential of a nitrosylating agent in the treatment of ovarian cancer. 2014 1
44 24922005 Antitumor efficacy of the anti-interleukin-6 (IL-6) antibody siltuximab in mouse xenograft models of lung cancer. 2014 Jul 1
45 24983364 Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumours. 2014 Aug 26 1
46 25200186 GPR30 mediates anorectic estrogen-induced STAT3 signaling in the hypothalamus. 2014 Nov 2
47 25275304 JAK2/STAT3 inhibition attenuates noise-induced hearing loss. 2014 1
48 25512545 STAT3 promotes survival of mutant photoreceptors in inherited photoreceptor degeneration models. 2014 Dec 30 2
49 23114963 Interleukin-6 promotes myogenic differentiation of mouse skeletal muscle cells: role of the STAT3 pathway. 2013 Jan 15 1
50 23376140 Hepatocytes display a compensatory survival response against cadmium toxicity by a mechanism mediated by EGFR and Src. 2013 Apr 1