2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

mitogen-activated protein kinase 3 ; Mus musculus







256 Article(s)
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1 34779492 The DR1‑CSE/H2S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice. 2022 Jan 1
2 35109789 Slc25a5 regulates adipogenesis by modulating ERK signaling in OP9 cells. 2022 Feb 2 2
3 32710469 NPY promotes macrophage migration by upregulating matrix metalloproteinase-8 expression. 2021 Mar 1
4 33505590 Cyclosporine A Promotes Bone Remodeling in LPS-Related Inflammation via Inhibiting ROS/ERK Signaling: Studies In Vivo and In Vitro. 2021 1
5 33771661 Roles of ERK/Akt signals in mitochondria-dependent and endoplasmic reticulum stress-triggered neuronal cell apoptosis induced by 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene, a major active metabolite of bisphenol A. 2021 May 15 1
6 34099438 Klotho prevents epithelial-mesenchymal transition through Egr-1 downregulation in diabetic kidney disease. 2021 Jun 1
7 34774495 Endothelial dysfunction caused by circulating microparticles from diabetic mice is reduced by PD98059 through ERK and ICAM-1. 2021 Dec 15 3
8 34803680 G Protein-Coupled Estrogen Receptor 30 Reduces Transverse Aortic Constriction-Induced Myocardial Fibrosis in Aged Female Mice by Inhibiting the ERK1/2 -MMP-9 Signaling Pathway. 2021 1
9 31653415 Antiapoptotic Effect by PAR-1 Antagonist Protects Mouse Liver Against Ischemia-Reperfusion Injury. 2020 Feb 1
10 32145325 5F peptide promotes endothelial differentiation of bone marrow stem cells through activation of ERK1/2 signaling. 2020 Jun 5 1
11 32606260 EphrinA1/EphA2 Promotes Epithelial Hyperpermeability Involving in Lipopolysaccharide-induced Intestinal Barrier Dysfunction. 2020 Jul 30 1
12 32706027 Epidermal growth factor signaling through transient receptor potential melastatin 7 cation channel regulates vascular smooth muscle cell function. 2020 Aug 14 1
13 32803867 BDNF promoted osteoblast migration and fracture healing by up-regulating integrin β1 via TrkB-mediated ERK1/2 and AKT signalling. 2020 Sep 1
14 32862787 Resveratrol suppresses insulin-like growth factor I-induced osteoblast migration: attenuation of the p44/p42 MAP kinase pathway. 2020 Dec 1
15 33659270 Xingbi Gel Ameliorates Allergic Rhinitis by Regulating IFN-γ Gene Promoter Methylation in CD4+ T Cells via the ERK-DNMT Pathway. 2020 1
16 30628054 Brain-derived neurotrophic factor: A steroidogenic regulator of Leydig cells. 2019 Aug 1
17 31014133 Dibutyl phthalate-induced activation of ROS and ERK1/2 causes hepatic and renal damage in Kunming mice. 2019 Aug 2
18 31287495 IGFBP7 regulates sepsis-induced epithelial-mesenchymal transition through ERK1/2 signaling. 2019 Aug 5 2
19 31678866 Activation of RAW264.7 macrophages by active fraction of Albizia julibrissin saponin via Ca2+-ERK1/2-CREB-lncRNA pathways. 2019 Dec 1
20 29136249 Natural Polyphenol Chlorogenic Acid Protects Against Acetaminophen-Induced Hepatotoxicity by Activating ERK/Nrf2 Antioxidative Pathway. 2018 Mar 1 1
21 29701904 TRPV4 activates cytosolic phospholipase A2 via Ca2+ -dependent PKC/ERK1/2 signalling in controlling hypertensive contraction. 2018 Apr 27 1
22 29768523 Extracellular calcium increases fibroblast growth factor 2 gene expression via extracellular signal-regulated kinase 1/2 and protein kinase A signaling in mouse dental papilla cells. 2018 May 14 1
23 30020824 Molecular mechanisms of somatostatin-mediated intestinal epithelial barrier function restoration by upregulating claudin-4 in mice with DSS-induced colitis. 2018 Oct 1 1
24 30123875 Thrombin-induced tolerance against oxygen-glucose deprivation in astrocytes: role of protease-activated receptor-1. 2018 Feb 1
25 30191630 FGF9/FGFR2 increase cell proliferation by activating ERK1/2, Rb/E2F1, and cell cycle pathways in mouse Leydig tumor cells. 2018 Nov 1
26 27840407 The natural product 4,10-aromadendranediol induces neuritogenesis in neuronal cells in vitro through activation of the ERK pathway. 2017 Jan 1
27 27905842 Airway smooth muscle cells from ovalbumin-sensitized mice show increased proliferative response to TGFβ1 due to upregulation of Smad3 and TGFβRII. 2017 Jun 1
28 27975141 Glucose and angiotensin II-derived endothelial extracellular vesicles regulate endothelial dysfunction via ERK1/2 activation. 2017 Feb 1
29 28034754 LXR agonists promote the proliferation of neural progenitor cells through MEK-ERK pathway. 2017 Jan 29 1
30 28235709 Role of ERK1/2 activation and nNOS uncoupling on endothelial dysfunction induced by lysophosphatidylcholine. 2017 Mar 1
31 28303501 Isoflurane Postconditioning Inhibits tPA-Induced Matrix Metalloproteinases Activation After Hypoxic Injury via Low-Density Lipoprotein Receptor-Related Protein and Extracellular Signal-Regulated Kinase Pathway. 2017 May 1
32 28405172 Mitogen-activated protein kinase phosphatase-3 (MKP-3) in the surgical wound is necessary for the resolution of postoperative pain in mice. 2017 1
33 28455747 Oxidative stress promotes myocardial fibrosis by upregulating KCa3.1 channel expression in AGT-REN double transgenic hypertensive mice. 2017 Sep 1
34 28560384 Hydrogen sulfide inhibits mitochondrial fission in neuroblastoma N2a cells through the Drp1/ERK1/2 signaling pathway. 2017 Jul 2
35 28742995 Icaritin induces MC3T3-E1 subclone14 cell differentiation through estrogen receptor-mediated ERK1/2 and p38 signaling activation. 2017 Oct 1
36 28894350 Short-Term Regulation of FcγR-Mediated Phagocytosis by TLRs in Macrophages: Participation of 5-Lipoxygenase Products. 2017 1
37 29137434 Involment of RAS/ERK1/2 signaling and MEF2C in miR-155-3p inhibition-triggered cardiomyocyte differentiation of embryonic stem cell. 2017 Oct 13 1
38 29270590 [Antioxidant effects of celastrol against hydrogen peroxide-induced oxidative stress in the cell model of amyotrophic lateral sclerosis]. 2017 Dec 25 1
39 26454217 Honokiol induces autophagy of neuroblastoma cells through activating the PI3K/Akt/mTOR and endoplasmic reticular stress/ERK1/2 signaling pathways and suppressing cell migration. 2016 Jan 1 1
40 26624246 Differential regulation of angiotensin II-induced extracellular signal regulated kinase-1/2 and -5 in progressive glomerulonephritis. 2016 Nov 1
41 26647389 Exendin-4 promotes proliferation and differentiation of MC3T3-E1 osteoblasts by MAPKs activation. 2016 Apr 1
42 26655082 Roles of NMDARs in maintenance of the mouse cerebrovascular endothelial cell-constructed tight junction barrier. 2016 Jan 2 1
43 26975768 Longan (Dimocarpus longan Lour.) Fruit Extract Stimulates Osteoblast Differentiation via Erk1/2-Dependent RUNX2 Activation. 2016 Jun 28 1
44 27035884 Role of extracellular signal‑regulated kinase 1/2 signal transduction pathway in insulin secretion by β‑TC6 cells. 2016 May 1
45 27045084 MEK1/2 inhibitors induce interleukin-5 expression in mouse macrophages and lymphocytes. 2016 May 13 1
46 27216486 Disinhibition of the extracellular-signal-regulated kinase restores the amplification of circadian rhythms by lithium in cells from bipolar disorder patients. 2016 Aug 1
47 27259276 Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs. 2016 Jul 12 1
48 27261070 Metabotropic glutamate receptor 1 promotes cementoblast proliferation via MAP kinase signaling pathways. 2016 Sep 1
49 27264241 Increased production of omega-3 fatty acids protects retinal ganglion cells after optic nerve injury in mice. 2016 Jul 1
50 27322250 Cypermethrin Induces Macrophages Death through Cell Cycle Arrest and Oxidative Stress-Mediated JNK/ERK Signaling Regulated Apoptosis. 2016 Jun 17 2