| 1 |
35269738 | Amelioration of Endotoxin-Induced Acute Lung Injury and Alveolar Epithelial Cells Apoptosis by Simvastatin Is Associated with Up-Regulation of Survivin/NF-kB/p65 Pathway. | 2022 Feb 26 |
1 |
| 2 |
32633363 | Simvastatin induces apoptosis of nasopharyngeal carcinoma cells through NF-κB signaling pathway. | 2020 Jun |
2 |
| 3 |
32727400 | Anti-tumor effects of mevalonate pathway inhibition in ovarian cancer. | 2020 Jul 29 |
1 |
| 4 |
33008033 | Protective Effects of Simvastatin on Endotoxin-Induced Acute Kidney Injury through Activation of Tubular Epithelial Cells' Survival and Hindering Cytochrome C-Mediated Apoptosis. | 2020 Sep 30 |
3 |
| 5 |
33174049 | [Corrigendum] Effects of simvastatin on iNOS and caspase‑3 levels and oxidative stress following smoke inhalation injury. | 2020 Dec |
1 |
| 6 |
30813251 | The Combined Use of Phenothiazines and Statins Strongly Affects Doxorubicin-Resistance, Apoptosis, and Cox-2 Activity in Colon Cancer Cells. | 2019 Feb 22 |
1 |
| 7 |
31105786 | Inhibitory effect of simvastatin in nasopharyngeal carcinoma cells. | 2019 Jun |
1 |
| 8 |
31839714 | Statins induce cell apoptosis through a modulation of AKT/FOXO1 pathway in prostate cancer cells. | 2019 |
2 |
| 9 |
29208461 | Simvastatin inhibits the development of radioresistant esophageal cancer cells by increasing the radiosensitivity and reversing EMT process via the PTEN-PI3K/AKT pathway. | 2018 Jan 15 |
1 |
| 10 |
29532878 | Simvastatin exerts anticancer effects in osteosarcoma cell lines via geranylgeranylation and c-Jun activation. | 2018 Apr |
1 |
| 11 |
29664056 | Inhibitory Effects of Simvastatin on Oxidized Low-Density Lipoprotein-Induced Endoplasmic Reticulum Stress and Apoptosis in Vascular Endothelial Cells. | 2018 Apr 20 |
1 |
| 12 |
30038146 | The protective effect of simvastatin against ultraviolet B-induced corneal endothelial cell death. | 2018 Aug |
2 |
| 13 |
30503138 | Simvastatin, at clinically relevant concentrations, affects human uterine leiomyoma growth and extracellular matrix production. | 2018 Dec |
1 |
| 14 |
28968609 | Inhibition of Prenylation Promotes Caspase 3 Activation, Lamin B Degradation and Loss in Metabolic Cell Viability in Pancreatic β-Cells. | 2017 |
1 |
| 15 |
29113274 | Simvastatin potentiates doxorubicin activity against MCF-7 breast cancer cells. | 2017 Nov |
1 |
| 16 |
27098189 | Simvastatin and atorvastatin as inhibitors of proliferation and inducers of apoptosis in human cholangiocarcinoma cells. | 2016 May 15 |
1 |
| 17 |
27109251 | Activation of endothelial NO synthase by a xanthine derivative ameliorates hypoxia-induced apoptosis in endothelial progenitor cells. | 2016 Jun |
1 |
| 18 |
25738368 | Molecular mechanism underlying the anticancer effect of simvastatin on MDA-MB-231 human breast cancer cells. | 2015 Jul |
1 |
| 19 |
25840272 | Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study. | 2015 Aug |
1 |
| 20 |
26020489 | Tocilizumab unmasks a stage-dependent interleukin-6 component in statin-induced apoptosis of metastatic melanoma cells. | 2015 Aug |
1 |
| 21 |
26383260 | A mitochondrial DNA mutation influences the apoptotic effect of statins on prostate cancer. | 2015 Dec |
1 |
| 22 |
23924855 | Simvastatin inhibits proliferation and induces apoptosis in human lung cancer cells. | 2013 |
1 |
| 23 |
22012179 | Simvastatin protects human osteosarcoma cells from oxidative stress-induced apoptosis through mitochondrial-mediated signaling. | 2012 Feb |
2 |
| 24 |
23045963 | Effects of statins and farnesyl transferase inhibitors on ERK phosphorylation, apoptosis and cell viability in non-small lung cancer cells. | 2012 Dec |
1 |
| 25 |
21477071 | Effect of doublecortin on self-renewal and differentiation in brain tumor stem cells. | 2011 Jul |
1 |
| 26 |
21958871 | Involvement of Chk1-Cdc25A-cyclin A/CDK2 pathway in simvastatin induced S-phase cell cycle arrest and apoptosis in multiple myeloma cells. | 2011 Nov 30 |
1 |
| 27 |
20043868 | Stabilization and translocation of p53 to mitochondria is linked to Bax translocation to mitochondria in simvastatin-induced apoptosis. | 2010 Jan 22 |
1 |
| 28 |
19343037 | Simvastatin suppresses homocysteine-induced apoptosis in endothelial cells: roles of caspase-3, cIAP-1 and cIAP-2. | 2009 May |
2 |
| 29 |
19934968 | Effect of simvastatin on glioma cell proliferation, migration, and apoptosis. | 2009 Dec |
4 |
| 30 |
18068200 | 7-Ketocholesterol activates caspases-3/7, -8, and -12 in human microvascular endothelial cells in vitro. | 2008 Apr |
1 |
| 31 |
18199714 | Statin induces apoptosis and cell growth arrest in prostate cancer cells. | 2008 Jan |
1 |
| 32 |
18203325 | High concentration simvastatin induces apoptosis in fibroblast-like synoviocytes from patients with rheumatoid arthritis. | 2008 Feb |
1 |
| 33 |
17241114 | Simvastatin protects neurons from cytotoxicity by up-regulating Bcl-2 mRNA and protein. | 2007 Apr |
1 |
| 34 |
17428261 | Simvastatin inactivates beta1-integrin and extracellular signal-related kinase signaling and inhibits cell proliferation in head and neck squamous cell carcinoma cells. | 2007 Jun |
1 |
| 35 |
16868926 | Depletion of substrates for protein prenylation increases apoptosis in human periovulatory granulosa cells. | 2006 Oct |
1 |
| 36 |
15949312 | [Simvastatin induces eosinophil apoptosis in vitro]. | 2005 May |
6 |
| 37 |
16708807 | [Effect of simvastatin on the proliferation of human omental preadipocytes and caspase-3 expression]. | 2005 Dec |
2 |
| 38 |
15163549 | Apoptotic injury in cultured human hepatocytes induced by HMG-CoA reductase inhibitors. | 2004 Jun 15 |
1 |
| 39 |
12962723 | Simvastatin induces apoptosis of B-CLL cells by activation of mitochondrial caspase 9. | 2003 Sep |
1 |