sulforaphane

nuclear factor, erythroid derived 2, like 2 ; Mus musculus







198 Article(s)
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1 34272506 Sulforaphane activates anti-inflammatory microglia, modulating stress resilience associated with BDNF transcription. 2022 Apr 4
2 34559743 Sulforaphane-Dependent Up-Regulation of NRF2 Activity Alleviates Both Systemic Inflammatory Response and Lung Injury After Hemorrhagic Shock/Resuscitation in Mice. 2022 Feb 1 5
3 34654875 Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway. 2022 Jun 4
4 34823019 Nrf2 contributes to the benefits of exercise interventions on age-related skeletal muscle disorder via regulating Drp1 stability and mitochondrial fission. 2022 Jan 4
5 35041848 Sulforaphane improves cognitive dysfunction after surgery and anesthesia in mice: The role of Keap1-Nrf2 signaling. 2022 Apr 2
6 35157168 Sulforaphane Does Not Protect Right Ventricular Systolic and Diastolic Functions in Nrf2 Knockout Pulmonary Artery Hypertension Mice. 2022 Jun 2
7 35222401 Sulforaphane Exerts Beneficial Immunomodulatory Effects on Liver Tissue via a Nrf2 Pathway-Related Mechanism in a Murine Model of Hemorrhagic Shock and Resuscitation. 2022 5
8 35256941 Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways. 2022 Feb 4
9 35323110 Sulforaphane reduces obesity by reversing leptin resistance. 2022 Mar 24 3
10 35401114 Sulforaphane Attenuates Chronic Intermittent Hypoxia-Induced Brain Damage in Mice via Augmenting Nrf2 Nuclear Translocation and Autophagy. 2022 5
11 35595779 Regulation of BDNF transcription by Nrf2 and MeCP2 ameliorates MPTP-induced neurotoxicity. 2022 May 20 2
12 35600947 Sulforaphane Ameliorates Limb Ischemia/Reperfusion-Induced Muscular Injury in Mice by Inhibiting Pyroptosis and Autophagy via the Nrf2-ARE Pathway. 2022 1
13 33388347 Sulforaphane ameliorates ethanol plus carbon tetrachloride-induced liver fibrosis in mice through the Nrf2-mediated antioxidant response and acetaldehyde metabolization with inhibition of the LPS/TLR4 signaling pathway. 2021 Mar 2
14 33429019 Cysteamine assay for the evaluation of bioactive electrophiles. 2021 Feb 20 1
15 33563837 Nrf2 Regulates Granuloma Formation and Macrophage Activation during Mycobacterium avium Infection via Mediating Nramp1 and HO-1 Expressions. 2021 Feb 9 1
16 33592002 The anti-arthritis effect of sulforaphane, an activator of Nrf2, is associated with inhibition of both B cell differentiation and the production of inflammatory cytokines. 2021 2
17 33627628 Activation of BDNF by transcription factor Nrf2 contributes to antidepressant-like actions in rodents. 2021 Feb 24 2
18 33711331 Sulforaphane inhibits NLRP3 inflammasome activation in microglia through Nrf2-mediated miRNA alteration. 2021 May 1
19 33741493 Effects of in vivo treatment of mice with sulforaphane on repair of DNA pyridyloxylbutylation. 2021 Apr 30 2
20 33793066 Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 through epigenetic modification. 2021 May 1
21 33996874 The Challenges of Designing and Implementing Clinical Trials With Broccoli Sprouts… and Turning Evidence Into Public Health Action. 2021 2
22 34107274 Lipid accumulation-induced hepatocyte senescence regulates the activation of hepatic stellate cells through the Nrf2-antioxidant response element pathway. 2021 Aug 15 2
23 34200377 Aldosterone Negatively Regulates Nrf2 Activity: An Additional Mechanism Contributing to Oxidative Stress and Vascular Dysfunction by Aldosterone. 2021 Jun 7 1
24 34206048 Nrf2 Activation Attenuates Acrylamide-Induced Neuropathy in Mice. 2021 Jun 1 3
25 34271100 Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway. 2021 Dec 5
26 34829721 Sulforaphane-Mediated Nrf2 Activation Prevents Radiation-Induced Skin Injury through Inhibiting the Oxidative-Stress-Activated DNA Damage and NLRP3 Inflammasome. 2021 Nov 22 1
27 34942977 Murine Neonatal Oxidant Lung Injury: NRF2-Dependent Predisposition to Adulthood Respiratory Viral Infection and Protection by Maternal Antioxidant. 2021 Nov 24 1
28 34960110 Investigating the Potential for Sulforaphane to Attenuate Gastrointestinal Dysfunction in mdx Dystrophic Mice. 2021 Dec 20 2
29 31706979 Protective effects of sulforaphane on type 2 diabetes-induced cardiomyopathy via AMPK-mediated activation of lipid metabolic pathways and NRF2 function. 2020 Jan 3
30 31760092 Trans-4,4'-dihydroxystilbene ameliorates cigarette smoke-induced progression of chronic obstructive pulmonary disease via inhibiting oxidative stress and inflammatory response. 2020 May 20 1
31 31769924 Protective role of Nrf2 against ischemia reperfusion injury and cardiac allograft vasculopathy. 2020 May 2
32 32024151 Dietary Antioxidants Significantly Attenuate Hyperoxia-Induced Acute Inflammatory Lung Injury by Enhancing Macrophage Function via Reducing the Accumulation of Airway HMGB1. 2020 Feb 1 2
33 32033211 Protective Effects of Sulforaphane on Exercise-Induced Organ Damage via Inducing Antioxidant Defense Responses. 2020 Feb 4 1
34 32073640 Enhancing the Nrf2 Antioxidant Signaling Provides Protection Against Trichloroethene-mediated Inflammation and Autoimmune Response. 2020 May 1 2
35 32079911 Nrf2 Activation Enhances Muscular MCT1 Expression and Hypoxic Exercise Capacity. 2020 Aug 2
36 32108526 Sulforaphane prevents right ventricular injury and reduces pulmonary vascular remodeling in pulmonary arterial hypertension. 2020 Apr 1 3
37 32361680 Reductive stress impairs myogenic differentiation. 2020 Jul 2
38 32401383 Sulforaphane ameliorates serum starvation-induced muscle atrophy via activation of the Nrf2 pathway in cultured C2C12 cells. 2020 Sep 5
39 32416107 Inhibition of ferroptosis attenuates busulfan-induced oligospermia in mice. 2020 Jul 1
40 32641994 Sulforaphane elicts dual therapeutic effects on Renal Inflammatory Injury and crystal deposition in Calcium Oxalate Nephrocalcinosis. 2020 2
41 32710977 Sulforaphane alleviates ethanol-mediated central inhibition and reverses chronic stress-induced aggravation of acute alcoholism via targeting Nrf2-regulated catalase expression. 2020 Oct 1 1
42 32738361 Sulforaphane suppresses obesity-related glomerulopathy-induced damage by enhancing autophagy via Nrf2. 2020 Oct 1 2
43 32760724 AMPK Enhances Transcription of Selected Nrf2 Target Genes via Negative Regulation of Bach1. 2020 2
44 32895018 Overexpression of Central ACE2 (Angiotensin-Converting Enzyme 2) Attenuates the Pressor Response to Chronic Central Infusion of Ang II (Angiotensin II): A Potential Role for Nrf2 (Nuclear Factor [Erythroid-Derived 2]-Like 2). 2020 Nov 1
45 32940670 Sulforaphane prevents type 2 diabetes-induced nephropathy via AMPK-mediated activation of lipid metabolic pathways and Nrf2 antioxidative function. 2020 Sep 30 5
46 32949969 Nrf2-regulated redox signaling in brain endothelial cells adapted to physiological oxygen levels: Consequences for sulforaphane mediated protection against hypoxia-reoxygenation. 2020 Oct 3
47 33067900 Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling. 2020 Nov 3
48 33242767 Reductive stress promotes protein aggregation and impairs neurogenesis. 2020 Oct 1
49 30315662 Antitumor activity of sulforaphane in mice model of skin cancer via blocking sulfatase-2. 2019 Jan 1
50 30529165 Sulforaphane enriched transcriptome of lung mitochondrial energy metabolism and provided pulmonary injury protection via Nrf2 in mice. 2019 Feb 1 8