Title : Murine Neonatal Oxidant Lung Injury: NRF2-Dependent Predisposition to Adulthood Respiratory Viral Infection and Protection by Maternal Antioxidant.

Pub. Date : 2021 Nov 24

PMID : 34942977






1 Functional Relationships(s)
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1 To investigate the prenatal antioxidant effect on neonatal oxidative lung injury, time-pregnant Nrf2-/- and Nrf2+/+ mice were given an oral NRF2 agonist (sulforaphane) on embryonic days 11.5-17.5, and offspring were exposed to hyperoxia. sulforaphane nuclear factor, erythroid derived 2, like 2 Mus musculus