| 1 |
33792156 | Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds. | 2022 Jan |
2 |
| 2 |
35035668 | Methylglyoxal Scavengers Attenuate Angiogenesis Dysfunction Induced by Methylglyoxal and Oxygen-Glucose Deprivation. | 2022 |
4 |
| 3 |
35363883 | Crystal structures of human glyoxalase I and its complex with TLSC702 reveal inhibitor binding mode and substrate preference. | 2022 Jun |
2 |
| 4 |
35455754 | Clinical Implications of Glyoxalase1 Gene Polymorphism and Elevated Levels of the Reactive Metabolite Methylglyoxal in the Susceptibility of Type 2 Diabetes Mellitus in the Patients from Asir and Tabuk Regions of Saudi Arabia. | 2022 Apr 15 |
2 |
| 5 |
32809100 | Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation. | 2021 |
1 |
| 6 |
33315368 | Two-Substrate Glyoxalase I Mechanism: A Quantum Mechanics/Molecular Mechanics Study. | 2021 Jan 4 |
1 |
| 7 |
33360689 | Genomic GLO1 deletion modulates TXNIP expression, glucose metabolism, and redox homeostasis while accelerating human A375 malignant melanoma tumor growth. | 2021 Feb |
2 |
| 8 |
33540757 | Polymorphisms in Glyoxalase I Gene Are Not Associated with Glyoxalase I Expression in Whole Blood or Markers of Methylglyoxal Stress: The CODAM Study. | 2021 Feb 2 |
4 |
| 9 |
33644826 | Dicarbonyl stress, protein glycation and the unfolded protein response. | 2021 Jun |
3 |
| 10 |
33671767 | Biochemical Regulation of the Glyoxalase System in Response to Insulin Signaling. | 2021 Feb 22 |
1 |
| 11 |
33727737 | Increase in the peripheral blood methylglyoxal levels in 10% of hospitalized chronic schizophrenia patients. | 2021 Feb |
1 |
| 12 |
33966051 | Glyoxalase I disruption and external carbonyl stress impair mitochondrial function in human induced pluripotent stem cells and derived neurons. | 2021 May 8 |
4 |
| 13 |
34062923 | Methylglyoxal-Dependent Glycative Stress Is Prevented by the Natural Antioxidant Oleuropein in Human Dental Pulp Stem Cells through Nrf2/Glo1 Pathway. | 2021 May 1 |
6 |
| 14 |
34093768 | Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer. | 2021 Jul |
2 |
| 15 |
34199263 | Glyoxalase-1-Dependent Methylglyoxal Depletion Sustains PD-L1 Expression in Metastatic Prostate Cancer Cells: A Novel Mechanism in Cancer Immunosurveillance Escape and a Potential Novel Target to Overcome PD-L1 Blockade Resistance. | 2021 Jun 13 |
4 |
| 16 |
34298821 | Glyoxalase 1 Expression as a Novel Diagnostic Marker of High-Grade Prostatic Intraepithelial Neoplasia in Prostate Cancer. | 2021 Jul 19 |
4 |
| 17 |
34790575 | Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Spliceosome. | 2021 |
7 |
| 18 |
34835243 | Defective Glyoxalase 1 Contributes to Pathogenic Inflammation in Cystic Fibrosis. | 2021 Nov 11 |
2 |
| 19 |
34887734 | TNF-ɑ Induces Methylglyoxal Accumulation in Lumbar Herniated Disc of Patients With Radicular Pain. | 2021 |
3 |
| 20 |
31879183 | Recent advances in the discovery and development of glyoxalase I inhibitors. | 2020 Feb 15 |
4 |
| 21 |
32011880 | Quantum Mechanics/Molecular Mechanics Study of the Reaction Mechanism of Glyoxalase I. | 2020 Feb 17 |
2 |
| 22 |
32368974 | The Role of Glyoxalase in Glycation and Carbonyl Stress Induced Metabolic Disorders. | 2020 |
2 |
| 23 |
32413970 | Discovery of GLO1 New Related Genes and Pathways by RNA-Seq on A2E-Stressed Retinal Epithelial Cells Could Improve Knowledge on Retinitis Pigmentosa. | 2020 May 13 |
4 |
| 24 |
32524572 | Spectrophotometric Method for Determining Glyoxalase 1 Activity in Cerebral Cavernous Malformation (CCM) Disease. | 2020 |
4 |
| 25 |
32640624 | Adeno-Associated Viral Transfer of Glyoxalase-1 Blunts Carbonyl and Oxidative Stresses in Hearts of Type 1 Diabetic Rats. | 2020 Jul 6 |
1 |
| 26 |
32858501 | Glyoxalase system: A systematic review of its biological activity, related-diseases, screening methods and small molecule regulators. | 2020 Nov |
2 |
| 27 |
33166134 | Glyoxalase 1 Inhibitor Alleviates Autism-like Phenotype in a Prenatal Valproic Acid-Induced Mouse Model. | 2020 Nov 18 |
2 |
| 28 |
29160087 | Glyoxalase 1 Modulation in Obesity and Diabetes. | 2019 Jan 20 |
4 |
| 29 |
30306863 | Recent Advances in Glyoxalase-I Inhibition. | 2019 |
4 |
| 30 |
30421661 | Effect of metformin treatment in patients with type 2 diabetes with respect to glyoxalase 1 activity in atherosclerotic lesions. | 2019 Mar |
4 |
| 31 |
30580027 | Crocin attenuates methylglyoxal-induced osteoclast dysfunction by regulating glyoxalase, oxidative stress, and mitochondrial function. | 2019 Feb |
1 |
| 32 |
30947068 | Combination of pharmacophore modeling and 3D-QSAR analysis of potential glyoxalase-I inhibitors as anticancer agents. | 2019 Jun |
4 |
| 33 |
30995106 | Methylglyoxal triggers human aortic endothelial cell dysfunction via modulation of the KATP/MAPK pathway. | 2019 Jul 1 |
2 |
| 34 |
31133647 | Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal. | 2019 May 27 |
5 |
| 35 |
31174324 | Methylglyoxal Acts as a Tumor-Promoting Factor in Anaplastic Thyroid Cancer. | 2019 Jun 6 |
2 |
| 36 |
31208152 | 2-Iodo-4'-Methoxychalcone Attenuates Methylglyoxal-Induced Neurotoxicity by Activation of GLP-1 Receptor and Enhancement of Neurotrophic Signal, Antioxidant Defense and Glyoxalase Pathway. | 2019 Jun 16 |
2 |
| 37 |
31369791 | Effect of bergenin on RANKL-induced osteoclast differentiation in the presence of methylglyoxal. | 2019 Dec |
1 |
| 38 |
31438528 | Indole-4-carboxaldehyde Isolated from Seaweed, Sargassum thunbergii, Attenuates Methylglyoxal-Induced Hepatic Inflammation. | 2019 Aug 21 |
6 |
| 39 |
31482070 | Inhibition of Glyoxalase-I Leads to Reduced Proliferation, Migration and Colony Formation, and Enhanced Susceptibility to Sorafenib in Hepatocellular Carcinoma. | 2019 |
4 |
| 40 |
31517069 | Effect of piceatannol-rich passion fruit seed extract on human glyoxalase I-mediated cancer cell growth. | 2019 Dec |
2 |
| 41 |
31630312 | Discovery of a nanomolar inhibitor of the human glyoxalase-I enzyme using structure-based poly-pharmacophore modelling and molecular docking. | 2019 Sep |
2 |
| 42 |
31661534 | Common variants in glyoxalase I do not increase chronic pancreatitis risk. | 2019 |
2 |
| 43 |
31738028 | High expression of GLO1 indicates unfavorable clinical outcomes in glioma patients. | 2019 Nov 13 |
2 |
| 44 |
31794195 | Imaging Tumorous Methylglyoxal by an Activatable Near-Infrared Fluorescent Probe for Monitoring Glyoxalase 1 Activity. | 2019 Dec 17 |
8 |
| 45 |
28506645 | Multiple roles of glyoxalase 1-mediated suppression of methylglyoxal glycation in cancer biology-Involvement in tumour suppression, tumour growth, multidrug resistance and target for chemotherapy. | 2018 Apr |
1 |
| 46 |
29151157 | Potent apoptosis-inducing activity of erypoegin K, an isoflavone isolated from Erythrina poeppigiana, against human leukemia HL-60 cells. | 2018 Jan |
1 |
| 47 |
29170092 | KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease. | 2018 Feb 1 |
2 |
| 48 |
29307109 | miR-137 inhibits melanoma cell proliferation through downregulation of GLO1. | 2018 May |
4 |
| 49 |
29355739 | Nicotine induces apoptosis in human osteoblasts via a novel mechanism driven by H2O2 and entailing Glyoxalase 1-dependent MG-H1 accumulation leading to TG2-mediated NF-kB desensitization: Implication for smokers-related osteoporosis. | 2018 Mar |
4 |
| 50 |
29385039 | Glyoxalases in Urological Malignancies. | 2018 Jan 31 |
2 |