Title : Quantum Mechanics/Molecular Mechanics Study of the Reaction Mechanism of Glyoxalase I.

Pub. Date : 2020 Feb 17

PMID : 32011880






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Glyoxalase I (GlxI) is a member of the glyoxalase system, which is important in cell detoxification and converts hemithioacetals of methylglyoxal (a cytotoxic byproduct of sugar metabolism that may react with DNA or proteins and introduce nucleic acid strand breaks, elevated mutation frequencies, and structural or functional changes of the proteins) and glutathione into d-lactate. Pyruvaldehyde glyoxalase I Homo sapiens
2 Glyoxalase I (GlxI) is a member of the glyoxalase system, which is important in cell detoxification and converts hemithioacetals of methylglyoxal (a cytotoxic byproduct of sugar metabolism that may react with DNA or proteins and introduce nucleic acid strand breaks, elevated mutation frequencies, and structural or functional changes of the proteins) and glutathione into d-lactate. Pyruvaldehyde glyoxalase I Homo sapiens