2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

mitogen-activated protein kinase 1 ; Mus musculus







318 Article(s)
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1 34780974 PP2A Catalytic Subunit α promotes fibroblast activation and kidney fibrosis via ERK pathway. 2022 Feb 2
2 32964473 The Apelin-Apelin Receptor Axis Triggers Cholangiocyte Proliferation and Liver Fibrosis During Mouse Models of Cholestasis. 2021 Jun 1
3 33888116 Alisol A 24-acetate stimulates lipolysis in 3 T3-L1 adipocytes. 2021 Apr 22 2
4 33918237 Columbianadin Dampens In Vitro Inflammatory Actions and Inhibits Liver Injury via Inhibition of NF-κB/MAPKs: Impacts on OH Radicals and HO-1 Expression. 2021 Apr 2 2
5 34504556 Sema4C modulates the migration of primary tumor-associated lymphatic endothelial cells via an ERK-mediated pathway. 2021 Oct 2
6 34774495 Endothelial dysfunction caused by circulating microparticles from diabetic mice is reduced by PD98059 through ERK and ICAM-1. 2021 Dec 15 3
7 31768729 Müller cells derived neurotrophin-3 inhibits hypoxia-induced photoreceptor apoptosis via the TrkC/ERK pathway. 2020 Feb 1
8 31901006 Melochia corchorifolia extract inhibits melanogenesis in B16F10 mouse melanoma cells via activation of the ERK signaling. 2020 Sep 2
9 31992084 Pro-Renin Receptor Overexpression Promotes Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-Knockout Mice. 2020 Jun 1
10 32005517 Osteopontin heptamer peptide containing the RGD motif enhances the phagocytic function of microglia. 2020 Apr 2 1
11 32145325 5F peptide promotes endothelial differentiation of bone marrow stem cells through activation of ERK1/2 signaling. 2020 Jun 5 1
12 32183593 Inhibition of MEK/ERK upregulates GSH production and increases RANKL-induced osteoclast differentiation in RAW 264.7 cells. 2020 Dec 2
13 32392918 Oncogenic Ras downregulates mdr1b expression through generation of reactive oxygen species. 2020 May 1 1
14 32395078 Oncogenic Ras downregulates mdr1b expression through generation of reactive oxygen species. 2020 May 1 1
15 32397640 Prevention of Oxidative Stress-Induced Pancreatic Beta Cell Damage by Broussonetia Kazinoki Siebold Fruit Extract Via the ERK-Nox4 Pathway. 2020 May 10 1
16 32630811 Inhibitory Effects of Pinostilbene Hydrate on Melanogenesis in B16F10 Melanoma Cells via ERK and p38 Signaling Pathways. 2020 Jul 2 1
17 33659270 Xingbi Gel Ameliorates Allergic Rhinitis by Regulating IFN-γ Gene Promoter Methylation in CD4+ T Cells via the ERK-DNMT Pathway. 2020 1
18 31006055 Lactoferrin promotes hair growth in mice and increases dermal papilla cell proliferation through Erk/Akt and Wnt signaling pathways. 2019 Jul 1
19 31014133 Dibutyl phthalate-induced activation of ROS and ERK1/2 causes hepatic and renal damage in Kunming mice. 2019 Aug 1
20 31461345 Complement C3 exacerbates renal interstitial fibrosis by facilitating the M1 macrophage phenotype in a mouse model of unilateral ureteral obstruction. 2019 Nov 1 2
21 31653006 Anthocyanins from Hibiscus syriacus L. Inhibit Melanogenesis by Activating the ERK Signaling Pathway. 2019 Oct 24 2
22 28887333 Rapid estrogen receptor-α signaling mediated by ERK activation regulates vascular tone in male and ovary-intact female mice. 2018 Feb 1 2
23 29160030 Dihydromyricetin enhances glucose uptake by inhibition of MEK/ERK pathway and consequent down-regulation of phosphorylation of PPARγ in 3T3-L1 cells. 2018 Feb 1
24 29486182 Phytol suppresses melanogenesis through proteasomal degradation of MITF via the ROS-ERK signaling pathway. 2018 Apr 25 1
25 29620243 Knockdown of peroxiredoxin V increases glutamate‑induced apoptosis in HT22 hippocampal neuron cells. 2018 Jun 4
26 29846015 AKR1B10 activates diacylglycerol (DAG) second messenger in breast cancer cells. 2018 Oct 1
27 29932247 Protective properties of Huperzine A through activation Nrf2/ARE-mediated transcriptional response in X-rays radiation-induced NIH3T3 cells. 2018 Nov 1
28 30099299 Anti-melanogenesis effect of dehydroglyasperin C through the downregulation of MITF via the reduction of intracellular cAMP and acceleration of ERK activation in B16F1 melanoma cells. 2018 Oct 1
29 32002961 Anti-melanogenesis effect of dehydroglyasperin C through the downregulation of MITF via the reduction of intracellular cAMP and acceleration of ERK activation in B16F1 melanoma cells. 2018 Sep 1
30 28000844 Cytoprotective effects of esculetin against oxidative stress are associated with the upregulation of Nrf2-mediated NQO1 expression via the activation of the ERK pathway. 2017 Feb 1
31 28034754 LXR agonists promote the proliferation of neural progenitor cells through MEK-ERK pathway. 2017 Jan 29 1
32 28042007 Epigallocatechin-3-gallate promotes angiogenesis via up-regulation of Nfr2 signaling pathway in a mouse model of ischemic stroke. 2017 Mar 15 2
33 28190476 Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways. 2017 Feb 15 1
34 28326932 A critical role of spinal Shank2 proteins in NMDA-induced pain hypersensitivity. 2017 Jan 1
35 28373901 Reperfusion Therapy with Rapamycin Attenuates Myocardial Infarction through Activation of AKT and ERK. 2017 1
36 28464378 Bradykinin Promotes Cell Proliferation, Migration, Invasion, and Tumor Growth of Gastric Cancer Through ERK Signaling Pathway. 2017 Dec 1
37 28694172 Macrophage migration inhibitory factor mediates viability and apoptosis of PVM/Ms through PI3K/Akt pathway. 2017 Sep 30 1
38 28753056 Gamma-Irradiated Luteolin Inhibits 3-Isobutyl-1-Methylxanthine-Induced Melanogenesis Through the Regulation of CREB/MITF, PI3K/Akt, and ERK Pathways in B16BL6 Melanoma Cells. 2017 Aug 1
39 28790387 GSK3β and ERK regulate the expression of 78 kDa SG2NA and ectopic modulation of its level affects phases of cell cycle. 2017 Aug 8 1
40 28810254 Insulin Influences LPS-Induced TNF-α and IL-6 Release Through Distinct Pathways in Mouse Macrophages from Different Compartments. 2017 1
41 28849451 Taurine Chloramine Prevents Neuronal HT22 Cell Damage Through Nrf2-Related Heme Oxygenase-1. 2017 2
42 28915638 Oleoylethanolamide inhibits α-melanocyte stimulating hormone-stimulated melanogenesis via ERK, Akt and CREB signaling pathways in B16 melanoma cells. 2017 Aug 22 1
43 29033935 Cannabinoid Receptor 1 Participates in Liver Inflammation by Promoting M1 Macrophage Polarization via RhoA/NF-κB p65 and ERK1/2 Pathways, Respectively, in Mouse Liver Fibrogenesis. 2017 2
44 29037608 Chemokine CCL8 and its receptor CCR5 in the spinal cord are involved in visceral pain induced by experimental colitis in mice. 2017 Oct 1
45 29075038 20(S)-Protopanaxadiol enhances angiogenesis via HIF-1α-mediated VEGF secretion by activating p70S6 kinase and benefits wound healing in genetically diabetic mice. 2017 Oct 27 1
46 29285052 Suppression of Alzheimer's disease-related phenotypes by the heat shock protein 70 inducer, geranylgeranylacetone, in APP/PS1 transgenic mice via the ERK/p38 MAPK signaling pathway. 2017 Dec 3
47 26102008 Oxyresveratrol abrogates oxidative stress by activating ERK-Nrf2 pathway in the liver. 2016 Feb 5 1
48 26647389 Exendin-4 promotes proliferation and differentiation of MC3T3-E1 osteoblasts by MAPKs activation. 2016 Apr 1
49 26699907 Dual effects of acetylsalicylic acid on ERK signaling and Mitf transcription lead to inhibition of melanogenesis. 2016 Jan 1
50 26748310 Chaetocin inhibits IBMX-induced melanogenesis in B16F10 mouse melanoma cells through activation of ERK. 2016 Feb 5 1