Title : Gamma-Irradiated Luteolin Inhibits 3-Isobutyl-1-Methylxanthine-Induced Melanogenesis Through the Regulation of CREB/MITF, PI3K/Akt, and ERK Pathways in B16BL6 Melanoma Cells.

Pub. Date : 2017 Aug

PMID : 28753056






1 Functional Relationships(s)
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1 The anti-melanogenic effects of 70 kGy gamma-irradiated luteolin were attenuated by the treatment of two specific inhibitors (PD98059 and LY294002), and these results indicate that the anti-melanogenic effects were mediated by ERK and PI3K signaling pathways. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one mitogen-activated protein kinase 1 Mus musculus