| 1 |
32876513 | IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer. | 2021 Mar |
1 |
| 2 |
31786775 | Anti-inflammatory Effect of AZD6244 on Acrolein-Induced Neuroinflammation. | 2020 Jan |
1 |
| 3 |
30682205 | Oral Selumetinib Does Not Negatively Impact Photoreceptor Survival in Murine Experimental Retinal Detachment. | 2019 Jan 2 |
2 |
| 4 |
28070119 | OCD-like behavior is caused by dysfunction of thalamo-amygdala circuits and upregulated TrkB/ERK-MAPK signaling as a result of SPRED2 deficiency. | 2018 Feb |
1 |
| 5 |
30257106 | MicroRNA-21 mediates high phosphate-induced endothelial cell apoptosis. | 2018 Dec 1 |
1 |
| 6 |
27599525 | Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation. | 2017 Feb |
4 |
| 7 |
28916199 | ERK and ROCK functionally interact in a signaling network that is compensationally upregulated in Spinal Muscular Atrophy. | 2017 Dec |
1 |
| 8 |
27669459 | Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine. | 2016 Nov 1 |
1 |
| 9 |
22144664 | MEK1/2 inhibitor selumetinib (AZD6244) inhibits growth of ovarian clear cell carcinoma in a PEA-15-dependent manner in a mouse xenograft model. | 2012 Feb |
1 |
| 10 |
19723882 | AZD6244 (ARRY-142886) enhances the therapeutic efficacy of sorafenib in mouse models of gastric cancer. | 2009 Sep |
1 |
| 11 |
18172275 | The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel. | 2008 Jan 1 |
1 |
| 12 |
17237274 | Targeted inhibition of the extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) in the treatment of hepatocellular carcinoma. | 2007 Jan |
2 |
| 13 |
17876044 | AZD6244 and doxorubicin induce growth suppression and apoptosis in mouse models of hepatocellular carcinoma. | 2007 Sep |
1 |