Tyrosine

kinase insert domain receptor ; Homo sapiens







154 Article(s)
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1 33655823 Natural Sourced Inhibitors of EGFR, PDGFR, FGFR and VEGFRMediated Signaling Pathways as Potential Anticancer Agents. 2022 1
2 34524004 Apatinib Combined with Paclitaxel and Cisplatin Neoadjuvant Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma. 2022 May 1
3 35451751 SH2-Domain Protein Isolation Using Synthetic Phosphorylated Peptides to Study VEGFR2 Signaling. 2022 3
4 32866228 Preeclampsia and Increased Permeability Over the Blood-Brain Barrier: A Role of Vascular Endothelial Growth Receptor 2. 2021 Feb 18 2
5 33554592 Disruption of the Microtubule Network and Inhibition of VEGFR2 Phosphorylation by Cytotoxic N,O-Coordinated Pt(II) and Ru(II) Complexes of Trimethoxy Aniline-Based Schiff Bases. 2021 Mar 1 2
6 34742690 PEDF is an endogenous inhibitor of VEGF-R2 angiogenesis signaling in endothelial cells. 2021 Dec 3
7 31642192 Nuclear localization of the tyrosine kinase BMX mediates VEGFR2 expression. 2020 Jan 2
8 31935623 Recent advancements in the treatment of metastatic clear cell renal cell carcinoma: A review of the evidence using second-generation p-values. 2020 Jan 3 1
9 32044644 Optimizing treatment of renal cell carcinoma with VEGFR-TKIs: a comparison of clinical pharmacology and drug-drug interactions of anti-angiogenic drugs. 2020 Mar 1
10 32045054 Design, synthesis, and molecular docking of novel 2-arylbenzothiazole multiangiokinase inhibitors targeting breast cancer. 2020 Apr 1
11 32053964 Targeting Receptor Tyrosine Kinase VEGFR-2 in Hepatocellular Cancer: Rational Design, Synthesis and Biological Evaluation of 1,2-Disubstituted Benzimidazoles. 2020 Feb 11 1
12 32055714 Cabozantinib inhibits AXL- and MET-dependent cancer cell migration induced by growth-arrest-specific 6 and hepatocyte growth factor. 2020 Mar 1
13 30845793 Protein Tyrosine Phosphatase, Receptor Type B (PTPRB) Inhibits Brown Adipocyte Differentiation through Regulation of VEGFR2 Phosphorylation. 2019 Apr 28 1
14 31604823 No evidence of Gremlin1-mediated activation of VEGFR2 signaling in endothelial cells. 2019 Nov 29 1
15 31694662 Apatinib potentiates irradiation effect via suppressing PI3K/AKT signaling pathway in hepatocellular carcinoma. 2019 Nov 6 2
16 31712231 Tumour-bowel fistula as a possible complication of pazopanib therapy in retroperitoneal leiomyosarcoma. 2019 Nov 10 1
17 31764847 Three case reports: Temporal association between tyrosine-kinase inhibitor-induced hepatitis and immune checkpoint inhibitors in renal cell carcinoma. 2019 Nov 2
18 31787809 Virtual screening,docking and molecular dynamics simulation of selected phytochemical compounds bound to receptor tyrosine kinases:A correlative anti angiogenic study. 2019 1
19 31847469 Temporal Dynamics of VEGFA-Induced VEGFR2/FAK Co-Localization Depend on SHB. 2019 Dec 15 2
20 32010646 Metastatic Perivascular Epithelioid Cell Tumor Of The Kidney: A Case Report With Emphasis On Response To The Tyrosine-Kinase Inhibitor Sunitinib. 2019 1
21 29964354 Abstracts of the 68th annual meeting in University of Nottingham. 2018 Jul 2 4
22 28330784 Vascular endothelial growth factor (VEGF) and VEGF receptor inhibitors in the treatment of renal cell carcinomas. 2017 Jun 2
23 28424170 ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis. 2017 Jun 1 1
24 28817576 Gestational diabetes mellitus is associated with increased pro-migratory activation of vascular endothelial growth factor receptor 2 and reduced expression of vascular endothelial growth factor receptor 1. 2017 4
25 26993523 Chronic high-magnitude cyclic stretch stimulates EC inflammatory response via VEGF receptor 2-dependent mechanism. 2016 Jun 1 2
26 27266812 Inhibition of vascular endothelial growth factor reduces cardiac allograft vasculopathy. 2016 Sep 1
27 27662093 Evidence for Pro-angiogenic Functions of VEGF-Ax. 2016 Sep 22 1
28 25102966 VEGF Receptor 2 (VEGFR2) Activation Is Essential for Osteocyte Survival Induced by Mechanotransduction. 2015 Feb 2
29 25161153 Emerging roles of post-translational modifications in signal transduction and angiogenesis. 2015 Jan 1
30 25354586 Carbon monoxide inhibits sprouting angiogenesis and vascular endothelial growth factor receptor-2 phosphorylation. 2015 Feb 1
31 25698653 Peptide Lv augments L-type voltage-gated calcium channels through vascular endothelial growth factor receptor 2 (VEGFR2) signaling. 2015 May 1
32 25967108 The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer. 2015 May 13 1
33 25990504 VEGF111b, a C-terminal splice variant of VEGF-A and induced by mitomycin C, inhibits ovarian cancer growth. 2015 May 20 2
34 26067165 Site-Specific Phosphorylation of VEGFR2 Is Mediated by Receptor Trafficking: Insights from a Computational Model. 2015 Jun 3
35 26327764 Carvedilol may attenuate liver cirrhosis by inhibiting angiogenesis through the VEGF-Src-ERK signaling pathway. 2015 Aug 28 1
36 26413215 Impact of MET targeting on tumor-associated angiogenesis and growth of MET mutations-driven models of liver cancer. 2015 Jul 1
37 24112971 The impact of the receptor binding profiles of the vascular endothelial growth factors on their angiogenic features. 2014 Jan 1
38 24129914 Recombinant human kallistatin inhibits angiogenesis by blocking VEGF signaling pathway. 2014 Mar 1
39 24508097 Increased placental angiogenesis in late and early onset pre-eclampsia is associated with differential activation of vascular endothelial growth factor receptor 2. 2014 Mar 2
40 25237397 Impaired Cav-1 expression in SSc mesenchymal cells upregulates VEGF signaling: a link between vascular involvement and fibrosis. 2014 1
41 25657827 The P2Y2 Receptor Interacts with VE-Cadherin and VEGF Receptor-2 to Regulate Rac1 Activity in Endothelial Cells. 2014 Dec 1 1
42 23583373 Early VEGFR2 activation in response to flow is VEGF-dependent and mediated by MMP activity. 2013 May 10 2
43 23636508 The enzymatic activity of the VEGFR2 receptor for the biosynthesis of dinucleoside polyphosphates. 2013 Sep 1
44 22363548 Integrin β3 crosstalk with VEGFR accommodating tyrosine phosphorylation as a regulatory switch. 2012 1
45 21316260 Targeting phosphoinositide 3-kinase signalling in lung cancer. 2011 Nov 1
46 21402774 PEST motif serine and tyrosine phosphorylation controls vascular endothelial growth factor receptor 2 stability and downregulation. 2011 May 1
47 21752276 Autocrine activity of soluble Flt-1 controls endothelial cell function and angiogenesis. 2011 Jul 13 2
48 21937443 Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes. 2011 Nov 18 1
49 22016776 Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3. 2011 1
50 22174934 Phosphorylation of Akt and ERK1/2 is required for VEGF-A/VEGFR2-induced proliferation and migration of lymphatic endothelium. 2011 1