Pub. Date : 2022
PMID : 35451751
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The first signal induced by VEGF binding to VEGFR2, is the activation of the receptor tyrosine kinase and autophosphorylation of intracellular tyrosine residues of the receptor. | Tyrosine | kinase insert domain receptor | Homo sapiens |
| 2 | In endothelial cells, five tyrosine residues in the VEGFR2 intracellular domain are essential in signal transmission and in the respective regulation of cellular processes. | Tyrosine | kinase insert domain receptor | Homo sapiens |
| 3 | Using this method, we identified and verified two proteins, growth factor receptor binding-2 (GRB2) and phosphoinositide 3"-kinase (PI3Kp85), binding to the tyrosine 1214 of VEGFR2. | Tyrosine | kinase insert domain receptor | Homo sapiens |