Serine

transmembrane serine protease 2 ; Homo sapiens







140 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34042026 Interfering with Host Proteases in SARS-CoV-2 Entry as a Promising Therapeutic Strategy. 2022 1
2 34353250 Current Perspective of COVID-19 on Neurology: A Mechanistic Insight. 2022 1
3 34370633 Molecular Modeling Targeting Transmembrane Serine Protease 2 (TMPRSS2) as an Alternative Drug Target Against Coronaviruses. 2022 1
4 34561887 Proteolytic activation of SARS-CoV-2 spike protein. 2022 Jan 1
5 34826419 Hydroxychloroquine treatment on SARS-CoV-2 receptor ACE2, TMPRSS2 and NRP1 expression in human primary pterygium and conjunctival cells. 2022 Jan 1
6 34862332 A low aldosterone/renin ratio and high soluble ACE2 associate with COVID-19 severity. 2022 Mar 1 2
7 34915414 In vitro interaction of potential antiviral TMPRSS2 inhibitors with human serum albumin and cytochrome P 450 isoenzymes. 2022 Feb 2
8 34915500 Immunohistochemical and Transcriptional Analysis of SARS-CoV-2 Entry Factors and Renin-Angiotensin-Aldosterone System Components in Lethal COVID-19. 2022 1
9 35039793 Metadichol®: A Novel Nanolipid Formulation That Inhibits SARS-CoV-2 and a Multitude of Pathological Viruses In Vitro. 2022 1
10 35063125 The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2. 2022 Feb 8 1
11 35103351 Estradiol reduces ACE2 and TMPRSS2 mRNA levels in A549 human lung epithelial cells. 2022 Feb 1 1
12 35104687 A common TMPRSS2 variant has a protective effect against severe COVID-19. 2022 May 1
13 35128036 Discovery of novel TMPRSS2 inhibitors for COVID-19 using in silico fragment-based drug design, molecular docking, molecular dynamics, and quantum mechanics studies. 2022 2
14 35154056 Integrated Analysis Reveals the Characteristics and Effects of SARS-CoV-2 Maternal-Fetal Transmission. 2022 1
15 35160229 Angiotensin-Converting Enzyme 2 (ACE2), Transmembrane Peptidase Serine 2 (TMPRSS2), and Furin Expression Increases in the Lungs of Patients with Idiopathic Pulmonary Fibrosis (IPF) and Lymphangioleiomyomatosis (LAM): Implications for SARS-CoV-2 (COVID-19) Infections. 2022 Jan 31 1
16 35170548 Potential applications of prognostic and immunological marker transmembrane serine proteinase 2 in prediction, prevention and personalized treatment of lung cancer. 2022 Mar 3 1
17 35193695 Polymorphisms and mutations of ACE2 and TMPRSS2 genes are associated with COVID-19: a systematic review. 2022 Feb 22 1
18 35226423 Soluble ACE2 and TMPRSS2 Levels in the Serum of Asthmatic Patients. 2022 Feb 28 1
19 35277472 New AKT-dependent mechanisms of anti-COVID-19 action of high-CBD Cannabis sativa extracts. 2022 Mar 11 1
20 35320487 Association of androgenetic alopecia with a more severe form of COVID-19 infection. 2022 Mar 23 1
21 35331159 Regulation of SARS CoV-2 host factors in the kidney and heart in rats with 5/6 nephrectomy-effects of salt, ARB, DPP4 inhibitor and SGLT2 blocker. 2022 Mar 24 1
22 35338216 Enoxaparin augments alpha-1-antitrypsin inhibition of TMPRSS2, a promising drug combination against COVID-19. 2022 Mar 25 1
23 35344983 A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic. 2022 May 1
24 35345416 Identification of novel TMPRSS2 inhibitors against SARS-CoV-2 infection: a structure-based virtual screening and molecular dynamics study. 2022 Mar 23 1
25 35359837 ACE2 Expression in Organotypic Human Airway Epithelial Cultures and Airway Biopsies. 2022 1
26 35412356 Semi-Mechanistic Pharmacokinetic-Pharmacodynamic Model of Camostat Mesylate-Predicted Efficacy against SARS-CoV-2 in COVID-19. 2022 Apr 27 1
27 35412405 Can the immunological system of the upper respiratory tract, improved by physical exercise, act as a first immunological barrier against SARS-CoV-2? 2022 Apr 26 2
28 35430474 Molecular modelling identification of phytocompounds from selected African botanicals as promising therapeutics against druggable human host cell targets of SARS-CoV-2. 2022 Jul 1
29 35455738 The Predictive Value of Serum ACE2 and TMPRSS2 Concentrations in Patients with COVID-19-A Prospective Pilot Study. 2022 Apr 12 1
30 35458558 Investigations on SARS-CoV-2 Susceptibility of Domestic and Wild Animals Using Primary Cell Culture Models Derived from the Upper and Lower Respiratory Tract. 2022 Apr 16 1
31 35631327 Camostat Does Not Inhibit the Proteolytic Activity of Neutrophil Serine Proteases. 2022 Apr 20 1
32 32410502 First comprehensive computational analysis of functional consequences of TMPRSS2 SNPs in susceptibility to SARS-CoV-2 among different populations. 2021 Jul 1
33 32452644 Caution in the management of SARS-CoV-2 infection in males. 2021 Jan 1
34 32672528 Computer-aided screening for potential TMPRSS2 inhibitors: a combination of pharmacophore modeling, molecular docking and molecular dynamics simulation approaches. 2021 Sep 1
35 32936429 Gender susceptibility to COVID-19: a review of the putative role of sex hormones and X chromosome. 2021 May 1
36 32972339 Targeting Host Cell Proteases to Prevent SARS-CoV-2 Invasion. 2021 1
37 33035337 DockCoV2: a drug database against SARS-CoV-2. 2021 Jan 8 1
38 33098835 Translating bioactive peptides for COVID-19 therapy. 2021 Jan 5 1
39 33130280 Unravelling high-affinity binding compounds towards transmembrane protease serine 2 enzyme in treating SARS-CoV-2 infection using molecular modelling and docking studies. 2021 Jan 5 1
40 33141332 What is the significance of the conjunctiva as a potential transmission route for SARS-CoV-2 infections? 2021 Jan 1
41 33164230 Insights into disparities observed with COVID-19. 2021 Apr 1
42 33188579 Human mesenchymal stromal cells do not express ACE2 and TMPRSS2 and are not permissive to SARS-CoV-2 infection. 2021 Apr 1
43 33239231 Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19. 2021 Jan 2
44 33394891 Type 2 Immunity and Age Modify Gene Expression of Coronavirus-induced Disease 2019 Receptors in Eosinophilic Gastrointestinal Disorders. 2021 May 1 1
45 33397514 Mediators of SARS-CoV-2 entry are preferentially enriched in cardiomyocytes. 2021 Jan 4 2
46 33505639 Spontaneous binding of potential COVID-19 drugs (Camostat and Nafamostat) to human serine protease TMPRSS2. 2021 1
47 33556871 An update review of emerging small-molecule therapeutic options for COVID-19. 2021 May 1
48 33564221 Structural modeling and analysis of the SARS-CoV-2 cell entry inhibitor camostat bound to the trypsin-like protease TMPRSS2. 2021 1
49 33570381 Challenges for Targeting SARS-CoV-2 Proteases as a Therapeutic Strategy for COVID-19. 2021 Jun 11 1
50 33609069 Prostate adenocarcinoma and COVID-19: The possible impacts of TMPRSS2 expressions in susceptibility to SARS-CoV-2. 2021 Apr 2