Paclitaxel

mitogen-activated protein kinase 3 ; Homo sapiens







41 Article(s)
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1 34365218 Predicting response to platinum and non-platinum drugs through bioluminescence resonance energy transfer (BRET) based bio-molecular interactions in platinum resistant epithelial ovarian cancer. 2021 Nov 2
2 34685613 7-Epitaxol Induces Apoptosis and Autophagy in Head and Neck Squamous Cell Carcinoma through Inhibition of the ERK Pathway. 2021 Oct 2 3
3 31293426 Tetramethylpyrazine Enhances the Antitumor Effect of Paclitaxel by Inhibiting Angiogenesis and Inducing Apoptosis. 2019 1
4 31334335 FoxM1 Induced Paclitaxel Resistance via Activation of the FoxM1/PHB1/RAF-MEK-ERK Pathway and Enhancement of the ABCA2 Transporter. 2019 Sep 27 2
5 31786845 Effect of PD98059 on chemotherapy in patients with colorectal cancer through ERK1/2 pathway. 2019 Sep-Oct 2
6 30064123 Synergistic Anticancer Activity of Combined Use of Caffeic Acid with Paclitaxel Enhances Apoptosis of Non-Small-Cell Lung Cancer H1299 Cells in Vivo and in Vitro. 2018 1
7 30094097 Trametinib suppresses chemotherapy-induced cold and mechanical allodynia via inhibition of extracellular-regulated protein kinase 1/2 activation. 2018 2
8 30221728 Combination of pristimerin and paclitaxel additively induces autophagy in human breast cancer cells via ERK1/2 regulation. 2018 Nov 1
9 30429459 Sulforaphane metabolites reduce resistance to paclitaxel via microtubule disruption. 2018 Nov 14 1
10 28415580 The N-terminal polypeptide derived from viral macrophage inflammatory protein II reverses breast cancer epithelial-to-mesenchymal transition via a PDGFRα-dependent mechanism. 2017 Jun 6 1
11 29371916 The IL-17B-IL-17 receptor B pathway promotes resistance to paclitaxel in breast tumors through activation of the ERK1/2 pathway. 2017 Dec 26 1
12 27422607 DUSP1 induces paclitaxel resistance through the regulation of p-glycoprotein expression in human ovarian cancer cells. 2016 Sep 9 2
13 27563006 Anti-nociceptive roles of the glia-specific metabolic inhibitor fluorocitrate in paclitaxel-evoked neuropathic pain. 2016 Oct 1
14 27619088 Electrochemical approach for monitoring the effect of anti tubulin drugs on breast cancer cells based on silicon nanograss electrodes. 2016 Sep 28 1
15 23478574 Egr-1 enhances drug resistance of breast cancer by modulating MDR1 expression in a GGPPS-independent manner. 2013 Apr 2
16 23879997 [Molecular mechanism of chemosensitization to paclitaxel in human melanoma cells induced by targeting the EGFR signaling pathway]. 2013 Mar 1
17 21391217 Synergistic anti-tumor activity of isochaihulactone and paclitaxel on human lung cancer cells. 2012 Jan 3
18 21924351 CDK1, not ERK1/2 or ERK5, is required for mitotic phosphorylation of BIMEL. 2012 Jan 1
19 22005063 Paclitaxel induced B7-H1 expression in cancer cells via the MAPK pathway. 2011 Oct 2
20 19717209 Potentiation of paclitaxel-induced apoptosis by galectin-13 overexpression via activation of Ask-1-p38-MAP kinase and JNK/SAPK pathways and suppression of Akt and ERK1/2 activation in U-937 human macrophage cells. 2009 Dec 1
21 18487950 Differential impact of fibroblasts on the efficient cell death of lung cancer cells induced by paclitaxel and cisplatin. 2008 Aug 1
22 18594523 Chemosensitisation by manganese superoxide dismutase inhibition is caspase-9 dependent and involves extracellular signal-regulated kinase 1/2. 2008 Jul 22 1
23 18688857 Toll-like receptor-4 is expressed in meningiomas and mediates the antiproliferative action of paclitaxel. 2008 Oct 15 2
24 17400763 Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells. 2007 Jul 1
25 17936423 Cytoskeletal signaling by way of alpha-actinin-1 mediates ERK1/2 activation by repetitive deformation in human Caco2 intestinal epithelial cells. 2007 Nov 1
26 16395709 p38 MAPK turns hepatocyte growth factor to a death signal that commits ovarian cancer cells to chemotherapy-induced apoptosis. 2006 Jun 15 2
27 16397234 Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt. 2006 Jan 1 2
28 15590693 Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival. 2005 Feb 11 2
29 15592521 A novel CYR61-triggered 'CYR61-alphavbeta3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway. 2005 Jan 27 1
30 15657900 Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity. 2005 May 20 2
31 15688426 Novel indication for cancer therapy: Chk1 inhibition sensitizes tumor cells to antimitotics. 2005 Jul 1 1
32 15778245 MAP kinases in lung endothelial permeability induced by microtubule disassembly. 2005 Jul 1
33 15834684 Paclitaxel impairs endothelial cell adhesion but not cytokine-induced cellular adhesion molecule expression. 2005 May 1
34 14742744 Extracellular signal-regulated kinase/mitogen-activated protein kinases block internalization of delta-opioid receptors. 2004 May 1
35 15466208 Inhibition of the Raf-MEK1/2-ERK1/2 signaling pathway, Bcl-xL down-regulation, and chemosensitization of non-Hodgkin's lymphoma B cells by Rituximab. 2004 Oct 1 1
36 12555062 Paclitaxel induces inactivation of p70 S6 kinase and phosphorylation of Thr421 and Ser424 via multiple signaling pathways in mitosis. 2003 Jan 30 1
37 14688474 Sequence dependent exposure of mammary carcinoma cells to Taxotere and the MEK1/2 inhibitor U0126 causes enhanced cell killing in vitro. 2003 Nov-Dec 1
38 11461121 The role of ERK 1/2 and p38 MAP-kinase pathways in taxol-induced apoptosis in human ovarian carcinoma cells. 2001 Aug 1 6
39 11710832 Cross-talk between signalling pathways and the multidrug resistant protein MDR-1. 2001 Oct 19 2
40 10773023 Extracellular signal-regulated kinases are involved in the antiapoptotic effect of endothelin-1. 2000 May 2
41 10376521 Serine protease inhibitor TPCK prevents Taxol-induced cell death and blocks c-Raf-1 and Bcl-2 phosphorylation in human breast carcinoma cells. 1999 Jun 10 4