Title : The N-terminal polypeptide derived from viral macrophage inflammatory protein II reverses breast cancer epithelial-to-mesenchymal transition via a PDGFRα-dependent mechanism.

Pub. Date : 2017 Jun 6

PMID : 28415580






1 Functional Relationships(s)
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1 Together, these results indicated that CXCR4 overexpression drives acquired paclitaxel resistance, partly by activating the PDGFA and PDGFB/PDGFRalpha autocrine signaling loops that activate AKT and ERK1/2. Paclitaxel mitogen-activated protein kinase 3 Homo sapiens