Hydrogen

nuclear receptor subfamily 1 group I member 2 ; Homo sapiens







13 Article(s)
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Title
Pub. Year
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1 31561157 An in vitro and in silico investigation of human pregnane X receptor agonistic activity of poly- and perfluorinated compounds using the heuristic method-best subset and comparative similarity indices analysis. 2020 Feb 1
2 29757018 A current structural perspective on PXR and CAR in drug metabolism. 2018 Jun 1
3 28115241 Poly- and perfluorinated compounds activate human pregnane X receptor. 2017 Apr 1 1
4 28963450 SPA70 is a potent antagonist of human pregnane X receptor. 2017 Sep 29 1
5 24828006 Bazedoxifene-scaffold-based mimetics of solomonsterols A and B as novel pregnane X receptor antagonists. 2014 Jun 12 2
6 21117944 Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study. 2011 Apr 1
7 21145880 Evaluation of in vitro PXR-based assays and in silico modeling approaches for understanding the binding of a structurally diverse set of drugs to PXR. 2011 Mar 1 1
8 21805522 Activation of the human nuclear xenobiotic receptor PXR by the reverse transcriptase-targeted anti-HIV drug PNU-142721. 2011 Oct 1
9 18579710 Computational discovery of novel low micromolar human pregnane X receptor antagonists. 2008 Sep 1
10 18768384 Structural basis of human pregnane X receptor activation by the hops constituent colupulone. 2008 Dec 1
11 17576789 Human pregnane X receptor antagonists and agonists define molecular requirements for different binding sites. 2007 Sep 1
12 15807509 The identification of ligand features essential for PXR activation by pharmacophore modeling. 2005 Mar-Apr 1
13 15039302 Key structural features of ligands for activation of human pregnane X receptor. 2004 Apr 2