Pub. Date : 2004 Apr
PMID : 15039302
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Therefore, a hydrophobic moiety at the 5-position and a hydrogen-bond acceptor being sufficiently separated from the phenyl-ring are responsible for activation of hPXR by barbiturates. | Hydrogen | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 2 | These findings suggest that hydrophobicity of the ligand and adequate distance between the hydrogen-bond acceptor and the hydrophobic group are important for hPXR activation. | Hydrogen | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |