| 1 |
34829293 | High Pregnane X Receptor (PXR) Expression Is Correlated with Poor Prognosis in Invasive Breast Carcinoma. | 2021 Oct 20 |
1 |
| 2 |
34943889 | Phenobarbital Induces SLC13A5 Expression through Activation of PXR but Not CAR in Human Primary Hepatocytes. | 2021 Dec 1 |
4 |
| 3 |
32735318 | Comparison of the Hepatic Effects of Phenobarbital in Chimeric Mice Containing Either Rat or Human Hepatocytes With Humanized Constitutive Androstane Receptor and Pregnane X Receptor Mice. | 2020 Oct 1 |
3 |
| 4 |
32788213 | Nuclear receptor phosphorylation in xenobiotic signal transduction. | 2020 Nov 6 |
1 |
| 5 |
31436536 | Mechanistic Insights of Phenobarbital-Mediated Activation of Human but Not Mouse Pregnane X Receptor. | 2019 Sep |
12 |
| 6 |
29269410 | Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor. | 2018 Mar |
1 |
| 7 |
29219065 | Transactivation Assays that Identify Indirect and Direct Activators of Human Pregnane X Receptor (PXR, NR1I2) and Constitutive Androstane Receptor (CAR, NR1I3). | 2017 |
1 |
| 8 |
27713827 | Evaluation of a novel PXR-knockout in HepaRG™ cells. | 2016 Oct |
1 |
| 9 |
24690595 | Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors. | 2014 Jun |
1 |
| 10 |
20488228 | Lack of P-glycoprotein induction by rifampicin and phenobarbital in human lymphocytes. | 2010 Aug 16 |
1 |
| 11 |
20645062 | Metabonomic studies on human hepatocyte in primary culture. | 2010 |
1 |
| 12 |
19541828 | Genetic polymorphisms in the TATA box and upstream phenobarbital-responsive enhancer module of the UGT1A1 promoter have combined effects on UDP-glucuronosyltransferase 1A1 transcription mediated by constitutive androstane receptor, pregnane X receptor, or glucocorticoid receptor in human liver. | 2009 Sep |
1 |
| 13 |
18172616 | Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter. | 2008 Jun |
2 |
| 14 |
18332078 | Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction. | 2008 Jun |
1 |
| 15 |
18989830 | Efficient assessment of the utility of immortalized Fa2N-4 cells for cytochrome P450 (CYP) induction studies using multiplex quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and substrate cassette methodologies. | 2008 Dec |
2 |
| 16 |
15832810 | Induction of phase I, II and III drug metabolism/transport by xenobiotics. | 2005 Mar |
3 |
| 17 |
15849716 | Modulation of UDP-glucuronosyltransferase 1A1 in primary human hepatocytes by prototypical inducers. | 2005 |
1 |
| 18 |
14600250 | Induction of human CYP2C9 by rifampicin, hyperforin, and phenobarbital is mediated by the pregnane X receptor. | 2004 Feb |
4 |
| 19 |
12571232 | A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression. | 2003 Apr 18 |
2 |
| 20 |
12659874 | Troglitazone stimulates IGF-binding protein-1 by a PPAR gamma-independent mechanism. | 2003 Apr 4 |
1 |
| 21 |
14705863 | Regulation of drug and bile salt transporters in liver and intestine. | 2003 Nov |
1 |
| 22 |
12065438 | CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes. | 2002 Jul |
2 |
| 23 |
12181452 | Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding site. | 2002 Sep |
1 |
| 24 |
12369894 | Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes. | 2002 Oct |
3 |
| 25 |
12664659 | [The role of nuclear receptors in cytochrome P-450 induction by xenochemicals]. | 2002 |
1 |
| 26 |
11181490 | Induction of CYP2C genes in human hepatocytes in primary culture. | 2001 Mar |
1 |
| 27 |
11264453 | Phenobarbital response elements of cytochrome P450 genes and nuclear receptors. | 2001 |
3 |
| 28 |
11502872 | Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor. | 2001 Sep |
1 |
| 29 |
10462436 | P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR. | 1999 Sep 1 |
2 |