Pub. Date : 2021 Dec 1
PMID : 34943889
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phenobarbital Induces SLC13A5 Expression through Activation of PXR but Not CAR in Human Primary Hepatocytes. | Phenobarbital | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 2 | Here, we show that PB markedly elevates the expression of SLC13A5 through a pregnane X receptor (PXR)-dependent but CAR-independent signaling pathway. | Phenobarbital | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 3 | Here, we show that PB markedly elevates the expression of SLC13A5 through a pregnane X receptor (PXR)-dependent but CAR-independent signaling pathway. | Phenobarbital | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |
| 4 | Collectively, these data reveal PB as a potent inducer of SLC13A5 through the activation of PXR but not CAR in human primary hepatocytes. | Phenobarbital | nuclear receptor subfamily 1 group I member 2 | Homo sapiens |