Serine

AKT serine/threonine kinase 1 ; Rattus norvegicus







192 Article(s)
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1 34871769 GPR3 accelerates neurite outgrowth and neuronal polarity formation via PI3 kinase-mediating signaling pathway in cultured primary neurons. 2022 Jan 1
2 35562960 CDDO-Me Attenuates Clasmatodendrosis in CA1 Astrocyte by Inhibiting HSP25-AKT Mediated DRP1-S637 Phosphorylation in Chronic Epilepsy Rats. 2022 Apr 20 2
3 33321190 Triterpenoid saponins from Ilex cornuta protect H9c2 cardiomyocytes against H2O2-induced apoptosis by modulating Ezh2 phosphorylation. 2021 Apr 6 1
4 33804063 Exendin-4 Promotes Schwann Cell Survival/Migration and Myelination In Vitro. 2021 Mar 15 1
5 33986917 Inactivation of TOPK Caused by Hyperglycemia Blocks Diabetic Heart Sensitivity to Sevoflurane Postconditioning by Impairing the PTEN/PI3K/Akt Signaling. 2021 1
6 34259031 Modulation of Sirt1 and FoxO1 on Hypothalamic Leptin-Mediated Sympathetic Activation and Inflammation in Diet-Induced Obese Rats. 2021 Jul 20 1
7 34489184 L-carnitine and Co Q10 ameliorate potassium dichromate -induced acute brain injury in rats targeting AMPK/AKT/NF-κβ. 2021 Dec 1
8 35295738 Integrated UPLC-MS and Network Pharmacology Approach to Explore the Active Components and the Potential Mechanism of Yiqi Huoxue Decoction for Treating Nephrotic Syndrome. 2021 1
9 30486685 Effect of sub-toxic exposure to Malathion on glucose uptake and insulin signaling in L6 myoblast derived myotubes. 2020 Nov 1
10 31478211 Serine peptidase inhibitor Kazal type III (SPINK3) promotes BRL-3A cell proliferation by targeting the PI3K-AKT signaling pathway. 2020 Mar 1
11 31995605 Metabolic syndrome diminishes insulin-induced Akt activation and causes a redistribution of Akt-interacting proteins in cardiomyocytes. 2020 2
12 32411219 The Phosphatase PHLPP2 Plays a Key Role in the Regulation of Pancreatic Beta-Cell Survival. 2020 1
13 32525289 bFGF promotes neurological recovery from neonatal hypoxic-ischemic encephalopathy by IL-1β signaling pathway-mediated axon regeneration. 2020 Aug 1
14 32572927 The effect of myocardial infarction-associated transcript 2 (Mirt2) and miR-101 on sepsis-induced myocardial injury in rats. 2020 Jun 1
15 32587280 Neuroprotective effects of low-dose G-CSF plus meloxicam in a rat model of anterior ischemic optic neuropathy. 2020 Jun 25 1
16 30248393 Sub-toxic exposure to lindane activates redox sensitive kinases and impairs insulin signaling in muscle cell culture: The possible mechanism of lindane-induced insulin resistance. 2019 Feb 1
17 31092832 Possible activation of NRF2 by Vitamin E/Curcumin against altered thyroid hormone induced oxidative stress via NFĸB/AKT/mTOR/KEAP1 signalling in rat heart. 2019 May 15 1
18 31122091 Effect of Subtoxic DDT Exposure on Glucose Uptake and Insulin Signaling in Rat L6 Myoblast-Derived Myotubes. 2019 Jul/Aug 1
19 31463398 Insulin attenuates apoptosis in neuronal cells by an integrin-linked kinase-dependent mechanism. 2019 Aug 1
20 31618892 PI3K-AKT Signaling Activation and Icariin: The Potential Effects on the Perimenopausal Depression-Like Rat Model. 2019 Oct 15 1
21 29257256 Simvastatin ameliorates cognitive impairments via inhibition of oxidative stress‑induced apoptosis of hippocampal cells through the ERK/AKT signaling pathway in a rat model of senile dementia. 2018 Jan 1
22 29480936 TrkB-mediated activation of the phosphatidylinositol-3-kinase/Akt cascade reduces the damage inflicted by oxygen-glucose deprivation in area CA3 of the rat hippocampus. 2018 May 1
23 29693586 Ellagic Acid Alleviates Hepatic Oxidative Stress and Insulin Resistance in Diabetic Female Rats. 2018 Apr 25 1
24 29700212 Neonatal maternal deprivation impairs localized de novo activity-induced protein translation at the synapse in the rat hippocampus. 2018 Jun 29 1
25 30504707 Ciliary Neurotrophic Factor (CNTF) Protects Myocardial Cells from Oxygen Glucose Deprivation (OGD)/Re-Oxygenation via Activation of Akt-Nrf2 Signaling. 2018 1
26 28868045 Primary Blast-Induced Changes in Akt and GSK Phosphorylation in Rat Hippocampus. 2017 1
27 26341783 Insulin Signaling and Glucose Uptake in the Soleus Muscle of 30-Month-Old Rats After Calorie Restriction With or Without Acute Exercise. 2016 Mar 1
28 26592809 Periapical lesions decrease Akt serine phosphorylation and plasma membrane GLUT4 content in rat skeletal muscle. 2016 Sep 3
29 26893473 Endurance training in early life results in long-term programming of heart mass in rats. 2016 Feb 2
30 26924725 A high fat diet induces sex-specific differences in hepatic lipid metabolism and nitrite/nitrate in rats. 2016 Apr 1 1
31 26979522 Neuregulin-1β promotes glucose uptake via PI3K/Akt in neonatal rat cardiomyocytes. 2016 May 1 2
32 27129809 Cardioprotective Effects of Phenylethanoid Glycoside-rich Extract from Cistanche deserticola in Ischemia-Reperfusion-Induced Myocardial Infarction in Rats. 2016 Jul 1
33 27446335 Tanshinone IIA protects H9c2 cells from oxidative stress-induced cell death via microRNA-133 upregulation and Akt activation. 2016 Aug 1
34 27938661 Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration. 2016 Dec 12 1
35 25421217 High-fat diet induces endothelial dysfunction through a down-regulation of the endothelial AMPK-PI3K-Akt-eNOS pathway. 2015 Mar 1
36 25463524 Methamphetamine differentially affects BDNF and cell death factors in anatomically defined regions of the hippocampus. 2015 Feb 12 1
37 25670830 Mechanisms for independent and combined effects of calorie restriction and acute exercise on insulin-stimulated glucose uptake by skeletal muscle of old rats. 2015 Apr 1 2
38 25988944 Inhibition of connexin43 improves functional recovery after ischemic brain injury in neonatal rats. 2015 Sep 1
39 26076958 Aurantio-obtusin relaxes systemic arteries through endothelial PI3K/AKT/eNOS-dependent signaling pathway in rats. 2015 Jul 1
40 26084330 L-Citrulline increases hepatic sensitivity to insulin by reducing the phosphorylation of serine 1101 in insulin receptor substrate-1. 2015 Jun 18 1
41 26289587 Endogenous BDNF augments NMDA receptor phosphorylation in the spinal cord via PLCγ, PKC, and PI3K/Akt pathways during colitis. 2015 Aug 20 1
42 26471759 Caffeine and contraction synergistically stimulate 5'-AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscle. 2015 Oct 1
43 26496899 Leptin signaling plays a critical role in the geniposide-induced decrease of tau phosphorylation. 2015 Dec 1
44 26658505 Subconjunctivally Implanted Hydrogels for Sustained Insulin Release to Reduce Retinal Cell Apoptosis in Diabetic Rats. 2015 Dec 1
45 24300170 Fluoride promotes osteoblastic differentiation through canonical Wnt/β-catenin signaling pathway. 2014 Feb 10 1
46 24332015 Phosphorylation of AKT and abdominal aortic aneurysm formation. 2014 Jan 2
47 24472754 Dihydrotestosterone deteriorates cardiac insulin signaling and glucose transport in the rat model of polycystic ovary syndrome. 2014 May 1
48 24490138 DHEA supplementation in ovariectomized rats reduces impaired glucose-stimulated insulin secretion induced by a high-fat diet. 2014 1
49 24619883 PPARγ activation attenuates glucose intolerance induced by mTOR inhibition with rapamycin in rats. 2014 May 1 1
50 25172224 Insulin inhibits AMPK activity and phosphorylates AMPK Ser⁴⁸⁵/⁴⁹¹ through Akt in hepatocytes, myotubes and incubated rat skeletal muscle. 2014 Nov 15 2