PP242

mechanistic target of rapamycin kinase ; Homo sapiens







60 Article(s)
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51 22401294 Antitumor activities of ATP-competitive inhibitors of mTOR in colon cancer cells. 2012 Mar 8 1
52 22476852 Targeting of mTORC2 prevents cell migration and promotes apoptosis in breast cancer. 2012 Aug 1
53 22556409 The PP242 mammalian target of rapamycin (mTOR) inhibitor activates extracellular signal-regulated kinase (ERK) in multiple myeloma cells via a target of rapamycin complex 1 (TORC1)/eukaryotic translation initiation factor 4E (eIF-4E)/RAF pathway and activation is a mechanism of resistance. 2012 Jun 22 1
54 22566604 Inhibition of the mTORC2 and chaperone pathways to treat leukemia. 2012 Jun 21 1
55 22685175 Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia. 2012 Jul 26 2
56 23026799 Aurora kinase A inhibition-induced autophagy triggers drug resistance in breast cancer cells. 2012 Dec 3
57 21615676 Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells. 2011 Oct 2
58 20072130 Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor. 2010 Feb 1
59 20227039 Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E. 2010 Mar 16 1
60 19209957 Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. 2009 Feb 10 2