Pub. Date : 2021 Aug
PMID : 33978839
4 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | Autophagy inhibitor potentiates the antitumor efficacy of apatinib in uterine sarcoma by stimulating PI3K/Akt/mTOR pathway. | apatinib | mechanistic target of rapamycin kinase | Homo sapiens | ||
| 2 | Apatinib inhibited the PI3K/Akt/mTOR pathway, while 3-MA and the combination of 3-MA and apatinib significantly activated the PI3K/Akt/mTOR pathway and inhibited autophagy. | apatinib | mechanistic target of rapamycin kinase | Homo sapiens | ||
| 3 | Apatinib inhibited the PI3K/Akt/mTOR pathway, while 3-MA and the combination of 3-MA and apatinib significantly activated the PI3K/Akt/mTOR pathway and inhibited autophagy. | apatinib | mechanistic target of rapamycin kinase | Homo sapiens | ||
| 4 | Autophagy inhibition may increase the antitumor effect of apatinib via the PI3K/Akt/mTOR pathway. | apatinib | mechanistic target of rapamycin kinase | Homo sapiens | ||