| 51 |
28260056 | Insulin-like growth factor 1 receptor-mediated cell survival in hypoxia depends on the promotion of autophagy via suppression of the PI3K/Akt/mTOR signaling pathway. | 2017 Apr |
1 |
| 52 |
28271613 | Qiliqiangxin protects against anoxic injury in cardiac microvascular endothelial cells via NRG-1/ErbB-PI3K/Akt/mTOR pathway. | 2017 Sep |
1 |
| 53 |
28524116 | Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells. | 2017 May 18 |
1 |
| 54 |
28731179 | Clinical significance of miR-138 in patients with malignant melanoma through targeting of PDK1 in the PI3K/AKT autophagy signaling pathway. | 2017 Sep |
1 |
| 55 |
28739349 | Autophagy protects against PI3K/Akt/mTOR-mediated apoptosis of spinal cord neurons after mechanical injury. | 2017 Aug 24 |
1 |
| 56 |
28807764 | Staphylococcal enterotoxin C2 mutant drives T lymphocyte activation through PI3K/mTOR and NF-ĸB signaling pathways. | 2017 Oct 15 |
1 |
| 57 |
28867195 | Simultaneous targeting PI3K and PERK pathways promotes cell death and improves the clinical prognosis in esophageal squamous carcinoma. | 2017 Nov 4 |
2 |
| 58 |
28881576 | Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis. | 2017 Aug 1 |
1 |
| 59 |
28968999 | Association of mSin1 with mTORC2 Ras and Akt reveals a crucial domain on mSin1 involved in Akt phosphorylation. | 2017 Sep 8 |
1 |
| 60 |
26490311 | Analysis of mTOR Gene Aberrations in Melanoma Patients and Evaluation of Their Sensitivity to PI3K-AKT-mTOR Pathway Inhibitors. | 2016 Feb 15 |
2 |
| 61 |
26647778 | TGF-β2 induces epithelial-mesenchymal transition in cultured human lens epithelial cells through activation of the PI3K/Akt/mTOR signaling pathway. | 2016 Feb |
1 |
| 62 |
26955235 | Dual-Blocking of PI3K and mTOR Improves Chemotherapeutic Effects on SW620 Human Colorectal Cancer Stem Cells by Inducing Differentiation. | 2016 Mar |
1 |
| 63 |
27007909 | Six1 induces protein synthesis signaling expression in duck myoblasts mainly via up-regulation of mTOR. | 2016 Mar |
1 |
| 64 |
27144449 | Green Tea Catechin Prevents Hypoxia/Reperfusion-Evoked Oxidative Stress-Regulated Autophagy-Activated Apoptosis and Cell Death in Microglial Cells. | 2016 May 25 |
1 |
| 65 |
27347100 | Gefitinib induces lung cancer cell autophagy and apoptosis via blockade of the PI3K/AKT/mTOR pathway. | 2016 Jul |
1 |
| 66 |
27357907 | Vitamin E succinate induces apoptosis via the PI3K/AKT signaling pathways in EC109 esophageal cancer cells. | 2016 Aug |
1 |
| 67 |
27604954 | nm23 regulates decidualization through the PI3K-Akt-mTOR signaling pathways in mice and humans. | 2016 Oct |
1 |
| 68 |
27748934 | Salidroside induces apoptosis and autophagy in human colorectal cancer cells through inhibition of PI3K/Akt/mTOR pathway. | 2016 Dec |
1 |
| 69 |
25355053 | Regulation of the cell cycle and PI3K/Akt/mTOR signaling pathway by tanshinone I in human breast cancer cell lines. | 2015 Feb |
1 |
| 70 |
25714853 | Targeting multiple tyrosine kinase receptors with Dovitinib blocks invasion and the interaction between tumor cells and cancer-associated fibroblasts in breast cancer. | 2015 |
1 |
| 71 |
25900077 | A Basal Tone of 2-Arachidonoylglycerol Contributes to Early Oligodendrocyte Progenitor Proliferation by Activating Phosphatidylinositol 3-Kinase (PI3K)/AKT and the Mammalian Target of Rapamycin (MTOR) Pathways. | 2015 Jun |
1 |
| 72 |
26096047 | Modulation of mTOR Activity by μ-Opioid Receptor is Dependent upon the Association of Receptor and FK506-Binding Protein 12. | 2015 Jul |
1 |
| 73 |
26622553 | miR-125a inhibits the migration and invasion of liver cancer cells via suppression of the PI3K/AKT/mTOR signaling pathway. | 2015 Aug |
1 |
| 74 |
26623104 | Phosphatidylethanolamine-binding protein 4 promotes lung cancer cells proliferation and invasion via PI3K/Akt/mTOR axis. | 2015 Oct |
2 |
| 75 |
24072614 | LY294002 and Rapamycin promote coxsackievirus-induced cytopathic effect and apoptosis via inhibition of PI3K/AKT/mTOR signaling pathway. | 2014 Jan |
2 |
| 76 |
24451985 | Stimulatory Effect of Vascular Endothelial Growth Factor on Proliferation and Migration of Porcine Trophectoderm Cells and Their Regulation by the Phosphatidylinositol-3-Kinase-AKT and Mitogen-Activated Protein Kinase Cell Signaling Pathways. | 2014 Mar |
1 |
| 77 |
24535016 | PI3K inhibitor LY294002 inhibits activation of the Akt/mTOR pathway induced by an oncolytic adenovirus expressing TRAIL and sensitizes multiple myeloma cells to the oncolytic virus. | 2014 Apr |
2 |
| 78 |
24700142 | SOX2 promotes the migration and invasion of laryngeal cancer cells by induction of MMP-2 via the PI3K/Akt/mTOR pathway. | 2014 Jun |
1 |
| 79 |
24774073 | β-Hydroxy-β-methylbutyrate facilitates PI3K/Akt-dependent mammalian target of rapamycin and FoxO1/3a phosphorylations and alleviates tumor necrosis factor α/interferon γ-induced MuRF-1 expression in C2C12 cells. | 2014 Apr |
1 |
| 80 |
24970817 | ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells. | 2014 Jul 15 |
1 |
| 81 |
25030585 | [Effect and mechanism of endoplasmic reticulum stress on cisplatin resistance in ovarian carcinoma]. | 2014 May |
1 |
| 82 |
25119993 | Isoegomaketone induces apoptosis in SK-MEL-2 human melanoma cells through mitochondrial apoptotic pathway via activating the PI3K/Akt pathway. | 2014 Nov |
1 |
| 83 |
23188704 | Upregulation of the antiapoptotic factor Livin contributes to cisplatin resistance in colon cancer cells. | 2013 Apr |
1 |
| 84 |
23266287 | Sevoflurane confers additive cardioprotection to ethanol preconditioning associated with enhanced phosphorylation of glycogen synthase kinase-3β and inhibition of mitochondrial permeability transition pore opening. | 2013 Oct |
1 |
| 85 |
23355370 | The PI3K/AKT signaling pathway controls the quiescence of the low-Rhodamine123-retention cell compartment enriched for melanoma stem cell activity. | 2013 Apr |
1 |
| 86 |
23373904 | LY294002 enhances expression of proteins encoded by recombinant replication-defective adenoviruses via mTOR- and non-mTOR-dependent mechanisms. | 2013 Mar 4 |
4 |
| 87 |
23660824 | Salidroside protects against hydrogen peroxide-induced injury in HUVECs via the regulation of REDD1 and mTOR activation. | 2013 Jul |
1 |
| 88 |
23793038 | Activation of the PI3K-AKT-mTOR signaling pathway promotes DEHP-induced Hep3B cell proliferation. | 2013 Sep |
2 |
| 89 |
23814023 | Dual inhibition of PI3K and mTOR mitigates compensatory AKT activation and improves tamoxifen response in breast cancer. | 2013 Oct |
1 |
| 90 |
23928058 | The small cell lung cancer-specific isoform of RE1-silencing transcription factor (REST) is regulated by neural-specific Ser/Arg repeat-related protein of 100 kDa (nSR100). | 2013 Oct |
1 |
| 91 |
24012499 | Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells. | 2013 Dec |
2 |
| 92 |
24205274 | Inhibition of IGF-1R prevents ionizing radiation-induced primary endothelial cell senescence. | 2013 |
1 |
| 93 |
22080879 | LY294002 and metformin cooperatively enhance the inhibition of growth and the induction of apoptosis of ovarian cancer cells. | 2012 Jan |
2 |
| 94 |
22357207 | Leptin regulates proliferation and apoptosis of colorectal carcinoma through PI3K/Akt/mTOR signalling pathway. | 2012 Mar |
1 |
| 95 |
22577264 | Induction of melanogenesis by rapamycin in human MNT-1 melanoma cells. | 2012 May |
2 |
| 96 |
22705730 | Atorvastatin enhances neurite outgrowth in cortical neurons in vitro via up-regulating the Akt/mTOR and Akt/GSK-3β signaling pathways. | 2012 Jul |
1 |
| 97 |
22863784 | Effect of advanced glycation end products on lectin-like oxidized low density lipoprotein receptor-1 expression in endothelial cells. | 2012 |
1 |
| 98 |
22985566 | [CA916798 gene participates in cisplatin resistance of human lung adenocarcinoma A549 cells through PI3K/AKT/mTOR pathway]. | 2012 Sep |
1 |
| 99 |
23275900 | PI3K/AKT/mTOR signaling pathway inhibitors in proliferation of retinal pigment epithelial cells. | 2012 |
4 |
| 100 |
21193390 | Fibulin-5 is up-regulated by hypoxia in endothelial cells through a hypoxia-inducible factor-1 (HIF-1α)-dependent mechanism. | 2011 Mar 4 |
1 |