Flavonoids

mechanistic target of rapamycin kinase ; Homo sapiens







28 Article(s)
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1 33167824 mTOR Targeted Cancer Chemoprevention by Flavonoids. 2021 3
2 33450548 Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against melanoma and non-melanoma skin cancers. 2021 Feb 1
3 33647348 Acacetin and pinostrobin as a promising inhibitor of cancer-associated protein kinases. 2021 May 1
4 33777154 Antitumor Effects of Baicalein and Its Mechanism via TGFβ Pathway in Cervical Cancer HeLa Cells. 2021 1
5 34348607 Flavonoids and PI3K/Akt/mTOR Signaling Cascade: A Potential Crosstalk in Anticancer Treatment. 2021 2
6 34560101 Myricetin slows liquid-liquid phase separation of Tau and activates ATG5-dependent autophagy to suppress Tau toxicity. 2021 Oct 1
7 34830339 Targeting PI3K/Akt/mTOR Pathway by Different Flavonoids: A Cancer Chemopreventive Approach. 2021 Nov 18 2
8 32168835 Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer's Disease. 2020 Mar 11 1
9 32257052 RNA-seq data analysis of stimulated hepatocellular carcinoma cells treated with epigallocatechin gallate and fisetin reveals target genes and action mechanisms. 2020 1
10 33143000 The Synthetic Flavonoid Derivative GL-V9 Induces Apoptosis and Autophagy in Cutaneous Squamous Cell Carcinoma via Suppressing AKT-Regulated HK2 and mTOR Signals. 2020 Oct 30 1
11 33389971 The Discovery of Druggable Anti-aging Agents. 2020 Dec 2
12 30766532 Immunomodulatory Effects of Flavonoids: Possible Induction of T CD4+ Regulatory Cells Through Suppression of mTOR Pathway Signaling Activity. 2019 3
13 29375715 Dietary flavonoid tangeretin induces reprogramming of epithelial to mesenchymal transition in prostate cancer cells by targeting the PI3K/Akt/mTOR signaling pathway. 2018 Jan 1
14 29491634 In silico Prediction and Wet Lab Validation of Arisaema tortuosum (Wall.) Schott Extracts as Antioxidant and Anti-breast Cancer Source: A Comparative Study. 2018 Jan 1
15 30050147 Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3Kγ mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway in human breast cancer cells. 2018 Jul 26 4
16 28251647 Changes of the phenolic compounds and antioxidant activities in germinated adlay seeds. 2017 Sep 1
17 28927111 Luteolin reduces migration of human glioblastoma cell lines via inhibition of the p-IGF-1R/PI3K/AKT/mTOR signaling pathway. 2017 Sep 1
18 27056897 Icariside II, a natural mTOR inhibitor, disrupts aberrant energy homeostasis via suppressing mTORC1-4E-BP1 axis in sarcoma cells. 2016 May 10 1
19 27221774 Flavonoid myricetin inhibits TNF-α-stimulated production of inflammatory mediators by suppressing the Akt, mTOR and NF-κB pathways in human keratinocytes. 2016 Aug 5 1
20 25625417 Structure-based grafting and identification of kinase-inhibitors to target mTOR signaling pathway as potential therapeutics for glioblastoma. 2015 Feb 1
21 25976993 Assessment of flavonoids and volatile compounds in tea infusions of water lily flowers and their antioxidant activities. 2015 Nov 15 1
22 23272907 Inhibition of mTOR signaling by quercetin in cancer treatment and prevention. 2013 Sep 2
23 23570274 Focal brain inflammation and autism. 2013 Apr 9 1
24 23688533 Is a subtype of autism an allergy of the brain? 2013 May 1
25 21618507 Dual inhibition of phosphatidylinositol 3-kinase/Akt and mammalian target of rapamycin signaling in human nonsmall cell lung cancer cells by a dietary flavonoid fisetin. 2012 Apr 1 1
26 22996344 Physicochemical and antioxidant properties of Algerian honey. 2012 Sep 20 1
27 21827150 Analysis of the antioxidant capacities of flavonoids under different spectrophotometric assays using cyclic voltammetry and density functional theory. 2011 Sep 28 1
28 20530556 Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells. 2010 Aug 1