Superoxides

mitogen-activated protein kinase 8 ; Homo sapiens







34 Article(s)
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1 34826531 Sequential delivery for hepatic fibrosis treatment based on carvedilol loaded star-like nanozyme. 2022 Jan 2
2 33732696 Deactivation of the JNK Pathway by GSTP1 Is Essential to Maintain Sperm Functionality. 2021 2
3 31759978 JNK activation and translocation to mitochondria mediates mitochondrial dysfunction and cell death induced by VDAC opening and sorafenib in hepatocarcinoma cells. 2020 Jan 1
4 32014500 Photobiomodulation (450 nm) alters the infection of periodontitis bacteria via the ROS/MAPK/mTOR signaling pathway. 2020 May 20 2
5 29207156 MAPK inhibitors, particularly the JNK inhibitor, increase cell death effects in H2O2-treated lung cancer cells via increased superoxide anion and glutathione depletion. 2018 Feb 3
6 27181592 JNK Activation Contributes to Oxidative Stress-Induced Parthanatos in Glioma Cells via Increase of Intracellular ROS Production. 2017 Jul 1
7 29183043 Benzo(e)pyrene Inhibits Endothelium-Dependent NO-Mediated Dilation of Retinal Arterioles via Superoxide Production and Endoplasmic Reticulum Stress. 2017 Nov 1 1
8 27838438 LRRC8A channels support TNFα-induced superoxide production by Nox1 which is required for receptor endocytosis. 2016 Dec 2
9 26001727 c-Jun N-terminal kinase attenuates TNFα signaling by reducing Nox1-dependent endosomal ROS production in vascular smooth muscle cells. 2015 Sep 1
10 24407242 JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death. 2014 Jan 9 2
11 24561578 OxLDL induces endothelial dysfunction and death via TRAF3IP2: inhibition by HDL3 and AMPK activators. 2014 May 1
12 25285524 Stathmin mediates hepatocyte resistance to death from oxidative stress by down regulating JNK. 2014 1
13 23283965 Synergistic triggering of superoxide flashes by mitochondrial Ca2+ uniport and basal reactive oxygen species elevation. 2013 Feb 15 1
14 23417568 SK-N-MC cell death occurs by distinct molecular mechanisms in response to hydrogen peroxide and superoxide anions: involvements of JAK2-STAT3, JNK, and p38 MAP kinases pathways. 2013 Jul 1
15 23559002 Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases. 2013 Apr 4 2
16 22222766 A superoxide-mediated mitogen-activated protein kinase phosphatase-1 degradation and c-Jun NH(2)-terminal kinase activation pathway for luteolin-induced lung cancer cytotoxicity. 2012 Apr 4
17 22906494 The effect of menadione on glutathione S-transferase A1 (GSTA1): c-Jun N-terminal kinase (JNK) complex dissociation in human colonic adenocarcinoma Caco-2 cells. 2012 Oct 2 1
18 21145826 Intracellular reactive oxygen species are required for directional migration of resident and bone marrow-derived hepatic pro-fibrogenic cells. 2011 May 1
19 21454558 Mitochondrial c-Jun N-terminal kinase (JNK) signaling initiates physiological changes resulting in amplification of reactive oxygen species generation. 2011 May 6 4
20 21460183 Whole genome siRNA cell-based screen links mitochondria to Akt signaling network through uncoupling of electron transport chain. 2011 May 15 2
21 21635550 Effect of N-nitrosodimethylamine on inducible nitric oxide synthase expression and production of nitric oxide by neutrophils and mononuclear cells: the role of JNK signalling pathway. 2011 Jul 1
22 21697181 Contribution of persistent C-Jun N-terminal kinase activity to the survival of human vestibular schwannoma cells by suppression of accumulation of mitochondrial superoxides. 2011 Sep 4
23 20139358 Oxidized low-density lipoprotein-activated c-Jun NH2-terminal kinase regulates manganese superoxide dismutase ubiquitination: implication for mitochondrial redox status and apoptosis. 2010 Mar 1
24 19846917 The effect of MAPK inhibitors on arsenic trioxide-treated Calu-6 lung cells in relation to cell death, ROS and GSH levels. 2009 Oct 1
25 18206660 Carbon monoxide blocks oxidative stress-induced hepatocyte apoptosis via inhibition of the p54 JNK isoform. 2008 Apr 1 3
26 18439101 Distinct role of c-Jun N-terminal kinase isoforms in human neutrophil apoptosis regulated by tumor necrosis factor-alpha and granulocyte-macrophage colony-stimulating factor. 2008 Apr 3
27 18440651 Interferon-gamma enhances human eosinophil effector functions induced by granulocyte-macrophage colony-stimulating factor or interleukin-5. 2008 Jun 15 1
28 16310883 Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: involvement of JNK and ERK MAP kinases. 2006 May 4
29 15569826 Atrial natriuretic peptide induces mitogen-activated protein kinase phosphatase-1 in human endothelial cells via Rac1 and NAD(P)H oxidase/Nox2-activation. 2005 Jan 7 2
30 15718491 C-reactive protein inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by activating p38 kinase and NAD(P)H oxidase. 2005 May 1
31 15993333 Activation of c-Jun-N-terminal kinase is required for apoptosis triggered by glutathione disulfide in neuroblastoma cells. 2005 Aug 1 2
32 15110391 p38 MAPK associated with stereoselective priming by grepafloxacin on O2- production in neutrophils. 2004 May 15 1
33 15145937 Hepatocyte resistance to oxidative stress is dependent on protein kinase C-mediated down-regulation of c-Jun/AP-1. 2004 Jul 23 1
34 11228746 Antioxidants differentially regulate activation of nuclear factor-kappa B, activator protein-1, c-jun amino-terminal kinases, and apoptosis induced by tumor necrosis factor: evidence that JNK and NF-kappa B activation are not linked to apoptosis. 1999 Summer 2