Title : Combining Patulin with Cadmium Induces Enhanced Hepatotoxicity and Nephrotoxicity In Vitro and In Vivo.

Pub. Date : 2021 Mar 18

PMID : 33803748






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 c-Jun N-terminal kinase 1 (JNK1) and p53 as downstream mediators of oxidative stress contributed to the synergistic toxicity by co-exposure of patulin and cadmium, while p53/JNK1 activation promoted the second-round ROS production through a positive feedback loop. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens
2 c-Jun N-terminal kinase 1 (JNK1) and p53 as downstream mediators of oxidative stress contributed to the synergistic toxicity by co-exposure of patulin and cadmium, while p53/JNK1 activation promoted the second-round ROS production through a positive feedback loop. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens