| 1 |
33183178 | Identification of natural inhibitors against prime targets of SARS-CoV-2 using molecular docking, molecular dynamics simulation and MM-PBSA approaches. | 2022 Apr |
3 |
| 2 |
33389441 | The anti-HCV, Sofosbuvir, versus the anti-EBOV Remdesivir against SARS-CoV-2 RNA dependent RNA polymerase in silico. | 2022 Feb |
2 |
| 3 |
33992054 | Structural Basis for the Understanding of Entry Inhibitors against SARS Viruses. | 2022 |
1 |
| 4 |
34920267 | Emerging mutations in the SARS-CoV-2 variants and their role in antibody escape to small molecule-based therapeutic resistance. | 2022 Feb |
1 |
| 5 |
35033572 | Very low levels of remdesivir resistance in SARS-COV-2 genomes after 18 months of massive usage during the COVID19 pandemic: A GISAID exploratory analysis. | 2022 Feb |
2 |
| 6 |
35185356 | Insight into the biological impact of COVID-19 and its vaccines on human health. | 2022 May |
4 |
| 7 |
35425333 | Molecular dynamics simulations and MM-GBSA reveal novel guanosine derivatives against SARS-CoV-2 RNA dependent RNA polymerase. | 2022 Jan 18 |
1 |
| 8 |
35435671 | Impact of Remdesivir Incorporation along the Primer Strand on SARS-CoV-2 RNA-Dependent RNA Polymerase. | 2022 May 23 |
7 |
| 9 |
35464436 | Identifying Small-Molecule Inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase by Establishing a Fluorometric Assay. | 2022 |
3 |
| 10 |
35465139 | Mechanism of reaction of RNA-dependent RNA polymerase from SARS-CoV-2. | 2022 May 19 |
1 |
| 11 |
35475235 | Unraveling the binding mechanism of the active form of Remdesivir to RdRp of SARS-CoV-2 and designing new potential analogues: Insights from molecular dynamics simulations. | 2022 Jul 16 |
2 |
| 12 |
35482820 | Mutations in the SARS-CoV-2 RNA dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms. | 2022 Apr 28 |
2 |
| 13 |
35510477 | Dual targeting of RdRps of SARS-CoV-2 and the mucormycosis-causing fungus: an in silico perspective. | 2022 Jul |
2 |
| 14 |
35634324 | Remdesivir and Its Combination With Repurposed Drugs as COVID-19 Therapeutics. | 2022 |
2 |
| 15 |
32338164 | SARS-CoV-2 RNA dependent RNA polymerase (RdRp) targeting: an in silico perspective. | 2021 Jun |
1 |
| 16 |
32686993 | Network analysis, sequence and structure dynamics of key proteins of coronavirus and human host, and molecular docking of selected phytochemicals of nine medicinal plants. | 2021 Oct |
1 |
| 17 |
32729392 | Antiviral potential of some novel structural analogs of standard drugs repurposed for the treatment of COVID-19. | 2021 Oct |
1 |
| 18 |
32836709 | Evaluating the potential of different inhibitors on RNA-dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2: A molecular modeling approach. | 2021 Jul |
1 |
| 19 |
32943188 | RNA-dependent RNA polymerase: Structure, mechanism, and drug discovery for COVID-19. | 2021 Jan 29 |
3 |
| 20 |
33176643 | Computational Evidences of Phytochemical Mediated Disruption of PLpro Driven Replication of SARS-CoV-2: A Therapeutic Approach against COVID-19. | 2021 |
1 |
| 21 |
33260103 | Mechanistic insight on the remdesivir binding to RNA-Dependent RNA polymerase (RdRp) of SARS-cov-2. | 2021 Feb |
6 |
| 22 |
33281478 | The potential of Paritaprevir and Emetine as inhibitors of SARS-CoV-2 RdRp. | 2021 Feb |
1 |
| 23 |
33347311 | Overview of Targets and Potential Drugs of SARS-CoV-2 According to the Viral Replication. | 2021 Jan 1 |
1 |
| 24 |
33376043 | Lycorine, a non-nucleoside RNA dependent RNA polymerase inhibitor, as potential treatment for emerging coronavirus infections. | 2021 Jun |
1 |
| 25 |
33421473 | Denovo designing, retro-combinatorial synthesis, and molecular dynamics analysis identify novel antiviral VTRM1.1 against RNA-dependent RNA polymerase of SARS CoV2 virus. | 2021 Feb 28 |
1 |
| 26 |
33436624 | Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. | 2021 Jan 12 |
3 |
| 27 |
33475021 | In silico study indicates antimalarials as direct inhibitors of SARS-CoV-2-RNA dependent RNA polymerase. | 2021 Jan 21 |
2 |
| 28 |
33490902 | High-throughput rational design of the remdesivir binding site in the RdRp of SARS-CoV-2: implications for potential resistance. | 2021 Jan 22 |
2 |
| 29 |
33491569 | RNA dependent RNA polymerase (RdRp) as a drug target for SARS-CoV2. | 2021 Jan 25 |
6 |
| 30 |
33556871 | An update review of emerging small-molecule therapeutic options for COVID-19. | 2021 May |
1 |
| 31 |
33561649 | Repurposing potential of Ayurvedic medicinal plants derived active principles against SARS-CoV-2 associated target proteins revealed by molecular docking, molecular dynamics and MM-PBSA studies. | 2021 May |
1 |
| 32 |
33565387 | Artificially expanded genetic information systems (AEGISs) as potent inhibitors of the RNA-dependent RNA polymerase of the SARS-CoV-2. | 2021 Feb 10 |
4 |
| 33 |
33615998 | In silico evaluation of isatin-based derivatives with RNA-dependent RNA polymerase of the novel coronavirus SARS-CoV-2. | 2021 Feb 22 |
7 |
| 34 |
33655751 | Biostructural Models for the Binding of Nucleoside Analogs to SARS-CoV-2 RNA-Dependent RNA Polymerase. | 2021 Mar 22 |
2 |
| 35 |
33688867 | 1'-Ribose cyano substitution allows Remdesivir to effectively inhibit nucleotide addition and proofreading during SARS-CoV-2 viral RNA replication. | 2021 Mar 14 |
2 |
| 36 |
33693066 | Structural analogues of existing anti-viral drugs inhibit SARS-CoV-2 RNA dependent RNA polymerase: A computational hierarchical investigation. | 2021 Mar |
1 |
| 37 |
33755983 | Early combination treatment with existing HIV antivirals: an effective treatment for COVID-19? | 2021 Mar |
1 |
| 38 |
33758867 | Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. | 2021 Mar 14 |
1 |
| 39 |
33766591 | A review on the interaction of nucleoside analogues with SARS-CoV-2 RNA dependent RNA polymerase. | 2021 Jun 30 |
1 |
| 40 |
33815808 | Computational insights of phytochemical-driven disruption of RNA-dependent RNA polymerase-mediated replication of coronavirus: a strategic treatment plan against coronavirus disease 2019. | 2021 May |
1 |
| 41 |
33841878 | Third force in the treatment of COVID-19: A systematic review and meta-analysis. | 2021 May |
1 |
| 42 |
33898520 | Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2. | 2021 |
3 |
| 43 |
33948598 | Allosteric activation of SARS-CoV-2 RdRp by remdesivir triphosphate and other phosphorylated nucleotides. | 2021 Apr 28 |
1 |
| 44 |
33984267 | Hepatitis C virus drugs that inhibit SARS-CoV-2 papain-like protease synergize with remdesivir to suppress viral replication in cell culture. | 2021 May 18 |
2 |
| 45 |
34069681 | Global Genomic Analysis of SARS-CoV-2 RNA Dependent RNA Polymerase Evolution and Antiviral Drug Resistance. | 2021 May 19 |
4 |
| 46 |
34136511 | Bioactive Molecules of Tea as Potential Inhibitors for RNA-Dependent RNA Polymerase of SARS-CoV-2. | 2021 |
2 |
| 47 |
34154407 | Allosteric Activation of SARS-CoV-2 RNA-Dependent RNA Polymerase by Remdesivir Triphosphate and Other Phosphorylated Nucleotides. | 2021 Jun 29 |
3 |
| 48 |
34165771 | Novel adenosine derivatives against SARS-CoV-2 RNA-dependent RNA polymerase: an in silico perspective. | 2021 Dec |
1 |
| 49 |
34206274 | Remdesivir MD Simulations Suggest a More Favourable Binding to SARS-CoV-2 RNA Dependent RNA Polymerase Mutant P323L Than Wild-Type. | 2021 Jun 22 |
11 |
| 50 |
34216889 | In silico analysis of RNA-dependent RNA polymerase of the SARS-CoV-2 and therapeutic potential of existing antiviral drugs. | 2021 Aug |
3 |