Decitabine

cytidine deaminase ; Homo sapiens







18 Article(s)
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Pub. Year
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1 33509441 A pilot clinical trial of oral tetrahydrouridine/decitabine for noncytotoxic epigenetic therapy of chemoresistant lymphoid malignancies. 2021 Jan 1
2 33904891 Cedazuridine/decitabine: from preclinical to clinical development in myeloid malignancies. 2021 Apr 27 1
3 32860582 Decitabine/Cedazuridine: First Approval. 2020 Sep 2
4 33042633 A pilot clinical trial of the cytidine deaminase inhibitor tetrahydrouridine combined with decitabine to target DNMT1 in advanced, chemorefractory pancreatic cancer. 2020 3
5 30926081 An oral fixed-dose combination of decitabine and cedazuridine in myelodysplastic syndromes: a multicentre, open-label, dose-escalation, phase 1 study. 2019 Apr 2
6 31370878 Novel prodrugs of decitabine with greater metabolic stability and less toxicity. 2019 Aug 1 2
7 27646854 Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma. 2016 Oct 2 3
8 26296954 Safety and tolerability of guadecitabine (SGI-110) in patients with myelodysplastic syndrome and acute myeloid leukaemia: a multicentre, randomised, dose-escalation phase 1 study. 2015 Sep 1
9 23287564 Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy. 2013 Feb 15 4
10 23479503 Myeloprotection by cytidine deaminase gene transfer in antileukemic therapy. 2013 Mar 1
11 21598398 Delineation of the molecular mechanisms of nucleoside recognition by cytidine deaminase through virtual screening. 2011 Aug 1 1
12 18221921 Simultaneous determination of decitabine and vorinostat (Suberoylanalide hydroxamic acid, SAHA) by liquid chromatography tandem mass spectrometry for clinical studies. 2008 Feb 15 1
13 16333246 The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia. 2005 Dec 12 2
14 11137229 Unnatural enantiomers of 5-azacytidine analogues: syntheses and enzymatic properties. 2000 Nov 1
15 9771951 Drug resistance to 5-aza-2'-deoxycytidine, 2',2'-difluorodeoxycytidine, and cytosine arabinoside conferred by retroviral-mediated transfer of human cytidine deaminase cDNA into murine cells. 1998 1
16 1375134 Potent inhibitors for the deamination of cytosine arabinoside and 5-aza-2'-deoxycytidine by human cytidine deaminase. 1992 1
17 1700230 Induction of cytidine deaminase in HL-60 myeloid leukemic cells by 5-aza-2'-deoxycytidine. 1990 2
18 6189497 Kinetics of deamination of 5-aza-2'-deoxycytidine and cytosine arabinoside by human liver cytidine deaminase and its inhibition by 3-deazauridine, thymidine or uracil arabinoside. 1983 Apr 1 1