Guanosine Triphosphate

Tu translation elongation factor, mitochondrial ; Homo sapiens







92 Article(s)
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1 32061931 Elongation Factor Tu Switch I Element is a Gate for Aminoacyl-tRNA Selection. 2020 Apr 17 1
2 32612237 Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading. 2020 Aug 2
3 33280582 Peculiarities in Activation of Hydrolytic Activity of Elongation Factors. 2020 Nov 1
4 29733411 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. 2018 Jun 20 3
5 30107527 Structural dynamics of translation elongation factor Tu during aa-tRNA delivery to the ribosome. 2018 Sep 19 3
6 30412578 Comparative structural dynamic analysis of GTPases. 2018 Nov 1
7 28138068 Ribosome dynamics during decoding. 2017 Mar 19 1
8 26786136 Centers of motion associated with EF-Tu binding to the ribosome. 2016 May 3 1
9 26888283 70S-scanning initiation is a novel and frequent initiation mode of ribosomal translation in bacteria. 2016 Mar 1 1
10 26971860 Review: Translational GTPases. 2016 Aug 1
11 25515218 The conformation of a catalytic loop is central to GTPase activity on the ribosome. 2015 Jan 20 1
12 25731854 Modeling the mechanisms of biological GTP hydrolysis. 2015 Sep 15 1
13 26338772 EF-Tu dynamics during pre-translocation complex formation: EF-Tu·GDP exits the ribosome via two different pathways. 2015 Oct 30 10
14 24345396 An unusual mechanism for EF-Tu activation during tmRNA-mediated ribosome rescue. 2014 Feb 1
15 24572811 Distinct functional classes of ram mutations in 16S rRNA. 2014 Apr 1
16 24671767 A tRNA body with high affinity for EF-Tu hastens ribosomal incorporation of unnatural amino acids. 2014 May 4
17 24778639 tmRNA-mediated trans-translation as the major ribosome rescue system in a bacterial cell. 2014 2
18 25126896 Labeled EF-Tus for rapid kinetic studies of pretranslocation complex formation. 2014 Oct 17 2
19 25246654 Rejection of tmRNA·SmpB after GTP hydrolysis by EF-Tu on ribosomes stalled on intact mRNA. 2014 Nov 1
20 24025161 Highly conserved base A55 of 16S ribosomal RNA is important for the elongation cycle of protein synthesis. 2013 Sep 24 1
21 23057558 Inefficient delivery but fast peptide bond formation of unnatural L-aminoacyl-tRNAs in translation. 2012 Oct 31 1
22 21152913 Molecular dynamics of ribosomal elongation factors G and Tu. 2011 Mar 2
23 21212264 Distortion of tRNA upon near-cognate codon recognition on the ribosome. 2011 Mar 11 1
24 20215430 Cleavage of the sarcin-ricin loop of 23S rRNA differentially affects EF-G and EF-Tu binding. 2010 Jul 1
25 20348441 Role of the C-terminal tail of SmpB in the early stage of trans-translation. 2010 May 1
26 19104062 Slow peptide bond formation by proline and other N-alkylamino acids in translation. 2009 Jan 6 1
27 19285947 Resampling and editing of mischarged tRNA prior to translation elongation. 2009 Mar 13 1
28 19524667 The R336Q mutation in human mitochondrial EFTu prevents the formation of an active mt-EFTu.GTP.aa-tRNA ternary complex. 2009 Aug 2
29 17130126 Chaperone properties of mammalian mitochondrial translation elongation factor Tu. 2007 Feb 9 2
30 16682558 Functional conformations of the L11-ribosomal RNA complex revealed by correlative analysis of cryo-EM and molecular dynamics simulations. 2006 Jul 2
31 16843583 Multiple stages in codon-anticodon recognition: double-trigger mechanisms and geometric constraints. 2006 Aug 2
32 16890341 Alignment/misalignment hypothesis for tRNA selection by the ribosome. 2006 Aug 1
33 15952884 Structural insights into translational fidelity. 2005 3
34 16023674 Ribosomal elongation cycle: energetic, kinetic and stereochemical aspects. 2005 Aug 19 1
35 14715237 Determination of the kinetics of guanine nucleotide exchange on EF-Tu and EF-Ts: continuing uncertainties. 2004 Jan 30 2
36 17194938 The ribosome as an RNA-based molecular machine. 2004 May 1
37 14550646 Purification and characterization of hexahistidine-tagged elongation factor SelB. 2003 Oct 1
38 14622005 Effects of mutagenesis of Gln97 in the switch II region of Escherichia coli elongation factor Tu on its interaction with guanine nucleotides, elongation factor Ts, and aminoacyl-tRNA. 2003 Nov 25 2
39 11907568 The transorientation hypothesis for codon recognition during protein synthesis. 2002 Mar 21 1
40 12023840 Functions and interplay of the tRNA-binding sites of the ribosome. 2002 Apr 1
41 12102560 Mechanisms of EF-Tu, a pioneer GTPase. 2002 1
42 12460565 EFG-independent translocation of the mRNA:tRNA complex is promoted by modification of the ribosome with thiol-specific reagents. 2002 Dec 6 1
43 11595738 Complex of transfer-messenger RNA and elongation factor Tu. Unexpected modes of interaction. 2001 Dec 14 6
44 10801827 Interaction of mitochondrial elongation factor Tu with aminoacyl-tRNA and elongation factor Ts. 2000 Jul 7 2
45 10937868 GTPases mechanisms and functions of translation factors on the ribosome. 2000 May-Jun 3
46 10600553 Animation of the dynamical events of the elongation cycle based on cryoelectron microscopy of functional complexes of the ribosome. 1999 Dec 1 1
47 9678602 Protein biosynthesis: structural studies of the elongation cycle. 1998 Jun 23 1
48 9701288 Release factor RF-3 GTPase activity acts in disassembly of the ribosome termination complex. 1998 Aug 1
49 9405422 Renaturation of rhodanese by translational elongation factor (EF) Tu. Protein refolding by EF-Tu flexing. 1997 Dec 19 2
50 8768893 Elongation in bacterial protein biosynthesis. 1996 Aug 1