Lysine

poly(ADP-ribose) polymerase 1 ; Homo sapiens







22 Article(s)
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1 34738744 Precise Diabetic Wound Therapy: PLS Nanospheres Eliminate Senescent Cells via DPP4 Targeting and PARP1 Activation. 2022 Jan 2
2 33681613 Computational Analysis Indicates That PARP1 Acts as a Histone Deacetylases Interactor Sharing Common Lysine Residues for Acetylation, Ubiquitination, and SUMOylation in Alzheimer's and Parkinson's Disease. 2021 Mar 2 2
3 33734501 SMURF2-mediated ubiquitin signaling plays an essential role in the regulation of PARP1 PARylating activity, molecular interactions, and functions in mammalian cells. 2021 Apr 1
4 33940558 PARP1: Structural insights and pharmacological targets for inhibition. 2021 Jul 1
5 34224364 VLX600 Disrupts Homologous Recombination and Synergizes with PARP Inhibitors and Cisplatin by Inhibiting Histone Lysine Demethylases. 2021 Sep 1
6 32323799 PLCε knockdown enhances the radiosensitivity of castration‑resistant prostate cancer via the AR/PARP1/DNA‑PKcs axis. 2020 May 1
7 31616951 MORC2 regulates DNA damage response through a PARP1-dependent pathway. 2019 Sep 19 2
8 27090907 Parp1 Deficiency Confers Defects in Chromatin Surveillance and Remodeling During Reprogramming by Nuclear Transfer. 2016 2
9 26149390 ARTD1 Suppresses Interleukin 6 Expression by Repressing MLL1-Dependent Histone H3 Trimethylation. 2015 Sep 1
10 24726141 The histone methyltransferase SMYD2 methylates PARP1 and promotes poly(ADP-ribosyl)ation activity in cancer cells. 2014 Mar 1
11 24920161 Phosphoproteomic approach to characterize protein mono- and poly(ADP-ribosyl)ation sites from cells. 2014 Aug 1 1
12 22451931 Caspase-7 uses an exosite to promote poly(ADP ribose) polymerase 1 proteolysis. 2012 Apr 10 1
13 21680843 SIRT6 promotes DNA repair under stress by activating PARP1. 2011 Jun 17 3
14 20525793 PARP1 ADP-ribosylates lysine residues of the core histone tails. 2010 Oct 2
15 19506301 The cytotoxic T lymphocyte protease granzyme A cleaves and inactivates poly(adenosine 5'-diphosphate-ribose) polymerase-1. 2009 Aug 6 1
16 19622798 Sumoylation of poly(ADP-ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function. 2009 Nov 1
17 18990703 Poly(ADP-ribose) polymerase-1 down-regulates BRCA2 expression through the BRCA2 promoter. 2008 Dec 26 1
18 16204234 Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription. 2005 Dec 9 1
19 14705947 Regulation of the enzymatic catalysis of poly(ADP-ribose) polymerase by dsDNA, polyamines, Mg2+, Ca2+, histones H1 and H3, and ATP. 2004 Jan 13 1
20 7991593 Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia. 1994 Dec 6 1
21 8473297 Identification of potential active-site residues in the human poly(ADP-ribose) polymerase. 1993 Apr 25 2
22 2121735 Expression and site-directed mutagenesis of the catalytic domain of human poly(ADP-ribose)polymerase in Escherichia coli. Lysine 893 is critical for activity. 1990 Nov 5 1