Title : Poly(ADP-ribose) polymerase-1 down-regulates BRCA2 expression through the BRCA2 promoter.

Pub. Date : 2008 Dec 26

PMID : 18990703






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Inhibition of Parp-1 activity (by 3-AB) reduced histone 3 lysine 9 acetylation and blocked Parp-1 binding to the BRCA2 promoter. Lysine poly(ADP-ribose) polymerase 1 Homo sapiens