Bilirubin

solute carrier organic anion transporter family member 1B1 ; Homo sapiens







39 Article(s)
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1 35552472 Gadoxetic acid-enhanced magnetic resonance imaging predicts hyperbilirubinemia induced by glecaprevir during hepatitis C virus treatment. 2022 May 12 1
2 34272713 Case Study 6: Deconvoluting Hyperbilirubinemia-Differentiating Between Hepatotoxicity and Reversible Inhibition of UGT1A1, MRP2, or OATP1B1 in Drug Development. 2021 1
3 32407928 Elucidation of OATP1B1 and 1B3 transporter function using transgenic rodent models and commonly known single nucleotide polymorphisms. 2020 Jul 15 2
4 32796590 Prediction of Drug-Induced Hyperbilirubinemia by In Vitro Testing. 2020 Aug 11 1
5 30636082 Associations between G6PD, OATP1B1 and BLVRA variants and susceptibility to neonatal hyperbilirubinaemia in a Chinese Han population. 2019 Sep 2
6 27943244 Genetic Variations in Bilirubin Metabolism Genes and Their Association with Unconjugated Hyperbilirubinemia in Adults. 2017 Jan 1
7 27977017 Effect of genetic variants of bilirubin metabolism on the degree of hyperbilirubinemia in African-American newborns. 2017 Apr 1
8 26146896 Genetic link with cholelithiasis among pediatric SCA Tunisian patients: Examples of UGT1A1, SLCO1A2 and SLCO1B1. 2016 Mar 1
9 25315738 Gene replacement therapy for genetic hepatocellular jaundice. 2015 Jun 2
10 26191226 Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis. 2015 1
11 26413716 A GWAS Study on Liver Function Test Using eMERGE Network Participants. 2015 1
12 23886114 In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia. 2014 Mar 2
13 24523126 Case study 5. Deconvoluting hyperbilirubinemia: differentiating between hepatotoxicity and reversible inhibition of UGT1A1, MRP2, or OATP1B1 in drug development. 2014 1
14 24865931 Combined effects of the UGT1A1 and OATP2 gene polymorphisms as major risk factor for unconjugated hyperbilirubinemia in Indian neonates. 2014 Aug 15 1
15 25204339 Mechanisms underlying benign and reversible unconjugated hyperbilirubinemia observed with faldaprevir administration in hepatitis C virus patients. 2014 Nov 2
16 25394009 Safety and efficacy of ombitasvir - 450/r and dasabuvir and ribavirin in HCV/HIV-1 co-infected patients receiving atazanavir or raltegravir ART regimens. 2014 1
17 25406570 [Research progress on the relationship between SLCO1B1 gene and neonatal jaundice]. 2014 Nov 2
18 22982575 Hereditary conjugated hyperbilirubinaemia: 37 years later. 2013 Feb 2
19 23243220 Influence of human OATP1B1, OATP1B3, and OATP1A2 on the pharmacokinetics of methotrexate and paclitaxel in humanized transgenic mice. 2013 Feb 15 1
20 23750830 Evaluating the in vitro inhibition of UGT1A1, OATP1B1, OATP1B3, MRP2, and BSEP in predicting drug-induced hyperbilirubinemia. 2013 Aug 5 3
21 24151358 New insights in bilirubin metabolism and their clinical implications. 2013 Oct 14 1
22 22232210 Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver. 2012 Feb 2
23 22749334 Effects of statin treatments and polymorphisms in UGT1A1 and SLCO1B1 on serum bilirubin levels in Chinese patients with hypercholesterolaemia. 2012 Aug 5
24 21500146 Neonatal hyperbilirubinemia and organic anion transporting polypeptide-2 gene mutations. 2011 Sep 1
25 21092521 [OATP 1B1 T521C/A388G is an important polymorphism gene related to neonatal hyperbilirubinemia]. 2010 Sep 7
26 19238116 Common variants of four bilirubin metabolism genes and their association with serum bilirubin and coronary artery disease in Chinese Han population. 2009 Apr 1
27 19414484 Genome-wide association meta-analysis for total serum bilirubin levels. 2009 Jul 15 3
28 19560444 Interaction of porphyrins with human organic anion transporting polypeptide 1B1. 2009 Nov 10 2
29 18499754 Organic anion transporter 1B1: an important factor in hepatic thyroid hormone and estrogen transport and metabolism. 2008 Sep 5
30 17973861 OATP1B1 polymorphism is a major determinant of serum bilirubin level but not associated with rifampicin-mediated bilirubin elevation. 2007 Dec 7
31 15965581 Molecular genetics of unconjugated hyperbilirubinemia in Taiwanese. 2005 2
32 15382119 Interleukin 1beta inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance. 2004 Oct 1
33 15535988 Inhibition of human organic anion transporting polypeptide OATP 1B1 as a mechanism of drug-induced hyperbilirubinemia. 2004 Nov 20 3
34 12568656 Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta-maternal liver tandem excretory pathway for foetal bilirubin. 2003 May 1 1
35 12670950 The human organic anion transport protein SLC21A6 is not sufficient for bilirubin transport. 2003 Jun 6 4
36 14705859 Pathophysiological factors affecting CAR gene expression. 2003 Nov 1
37 11134001 Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6. 2001 Mar 30 2
38 11483603 Characterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1 alpha. 2001 Oct 5 2
39 10644574 A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane. 2000 Jan 1